Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Masashi Miyano"'
Autor:
Hiromichi Saino, Tomohiro Sugiyabu, Go Ueno, Masaki Yamamoto, Yoshikazu Ishii, Masashi Miyano
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145869 (2015)
OXA-58 is a class D β-lactamase from the multi-drug resistant Acinetobacter baumannii. We determined the crystal structure of OXA-58 in a novel crystal, and revealed the structure of the substrate-binding cleft in a closed state, distinct from a pre
Externí odkaz:
https://doaj.org/article/c6c19cbc7f204c54a9c4cb48d2b9c78c
Autor:
Hironori Nishitsuji, Takaya Hayashi, Takuya Takahashi, Masashi Miyano, Mari Kannagi, Takao Masuda
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7825 (2009)
There has been accumulating evidence for the involvement of retroviral integrase (IN) in the reverse transcription of viral RNA. We previously identified a host factor, survival motor neuron-interacting protein 1 (SIP1/Gemin2) that binds to human imm
Externí odkaz:
https://doaj.org/article/9a7bec21bbfc48d3a145297b418b2716
Autor:
Motonao Nakamura, Keitaro Yamashita, Yoshiaki Kawano, Kunio Hirata, Takao Shimizu, Toshiaki Okuno, Masakatsu Hato, Masashi Miyano, Takehiko Yokomizo, Masaki Yamamoto, Shigeyuki Yokoyama, Tetsuya Hori
Publikováno v:
Nature Chemical Biology. 14:262-269
Most G-protein-coupled receptors (GPCRs) are stabilized in common in the inactive state by the formation of the sodium ion-centered water cluster with the conserved Asp2.50 inside the seven-transmembrane domain. We determined the crystal structure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d17ec6a6686d7103b61941307d7b5ac8
https://doi.org/10.1038/nchembio.2547
https://doi.org/10.1038/nchembio.2547
Autor:
Masashi Miyano, Mai Kinoshita, Shiori Hirano, Keita Kanzaki, Yoshiko Mori, Tetsuya Hori, Shuji Okochi, Toshiko Suzuki-Yamamoto, Yuki Kawakami, Ichika Shimoda, Hiromichi Saino, Shozo Yamamoto, Masumi Kimoto, Yoshitaka Takahashi, Mitsuaki Sugahara
Publikováno v:
Journal of Biochemistry. 161:79-86
The X-ray crystal structure of an anti-leukotriene (LT) C4 monoclonal antibody (mAbLTC) in complex with LTC4 was determined, however, crystallographic studies alone are not enough to fully understand the structures of the antigen-binding site. To elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa49fcbab478259ce5fa2fff6c0cc8d5
https://doi.org/10.1093/jb/mvw055
https://doi.org/10.1093/jb/mvw055
Publikováno v:
Biochemistry and Biophysics Reports. 4:243-249
In this study, we introduced structure-based rational mutations in the guinea pig leukotriene B4 receptor (gpBLT1) in order to enhance the stabilization of the protein. Elements thought to be unfavorable for the stability of gpBLT1 were extracted bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e96cdbca7486a8ee8bb6c81adaff88
https://doi.org/10.1016/j.bbrep.2015.09.007
https://doi.org/10.1016/j.bbrep.2015.09.007
Autor:
Isao Enami, Nobuo Kamiya, Masashi Miyano, Jian Ren Shen, Lirong Tian, Hanfa Zou, Takayoshi Tashiro, Guangye Han, Fangjun Wang, Keisuke Kawakami, Zheyi Liu, Yasufumi Umena, Tingyun Kuang, Hideyuki Adachi, Hideo Ago
Publikováno v:
The Journal of biological chemistry. 291(11)
Photosystem II (PSII) catalyzes light-induced water splitting, leading to the evolution of molecular oxygen indispensible for life on the earth. The crystal structure of PSII from cyanobacteria has been solved at an atomic level, but the structure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76bf467c77395e658fde7310738224dc
https://pubmed.ncbi.nlm.nih.gov/26757821
https://pubmed.ncbi.nlm.nih.gov/26757821
Publikováno v:
Acta Crystallographica Section F
Dodecyl-β-d-selenomaltoside in a leukotriene C4 synthase crystal exhibited sufficient anomalous diffraction for multiwavelength anomalous diffraction phasing.
Dodecyl-β-d-selenomaltoside (SeDDM) is a seleno-detergent with a β-glycosidic selen
Dodecyl-β-d-selenomaltoside (SeDDM) is a seleno-detergent with a β-glycosidic selen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45c7a85ca6554d72daf075f837907a4
http://europepmc.org/articles/PMC3232166
http://europepmc.org/articles/PMC3232166
Autor:
Masaki Yamamoto, Atsushi Nisawa, Yoko Ukita, Yoshihide Kanaoka, Daisuke Irikura, Go Ueno, Masashi Miyano, Hideo Ago, K. Frank Austen, Hiromichi Saino, Bing K. Lam
Publikováno v:
The Journal of Biological Chemistry
Leukotriene (LT) C(4) and its metabolites, LTD(4) and LTE(4), are involved in the pathobiology of bronchial asthma. LTC(4) synthase is the nuclear membrane-embedded enzyme responsible for LTC(4) biosynthesis, catalyzing the conjugation of two substra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37234ebcb4ccb87ea38a0a93d3e1d181
http://europepmc.org/articles/PMC3091245
http://europepmc.org/articles/PMC3091245
Autor:
Takehiko Yokomizo, Takao Shimizu, Koji Takio, Naoko Takahashi, Tetsuya Hori, Yo Sato, Motonao Nakamura, Masashi Miyano
Publikováno v:
Protein Expression and Purification. 72:66-74
The high yield expression of BLT1, a G-protein coupled receptor for leukotriene B(4), was established in Pichia pastoris for structural studies. Guinea pig BLT1 was expressed in a functional form without post-translational modifications for the rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd07254874e56ed3efd08de89283fa68
https://doi.org/10.1016/j.pep.2010.02.013
https://doi.org/10.1016/j.pep.2010.02.013
Autor:
Masashi Miyano, Hideo Ago
Publikováno v:
Nihon Kessho Gakkaishi. 52:69-75
Cysteinyl leukotriene has been known to be a major component of SRS-A (Slow Reacting Substance of Anaphylaxis). Inhibitors affecting on its biosynthesis and antagonists of its G-protein coupled receptor are therapeutic agents for acute inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db6798ad6350b297429ff023f1013853
https://doi.org/10.5940/jcrsj.52.69
https://doi.org/10.5940/jcrsj.52.69