Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Masashi Maekawa"'
Autor:
Ji-Won Lee, In-Hee Lee, Haruhisa Watanabe, Yunqing Liu, Kazuaki Sawada, Masashi Maekawa, Shunsuke Uehara, Yasuhiro Kobayashi, Yuuki Imai, Sek Won Kong, Tadahiro Iimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Osteoclasts uniquely resorb calcified bone matrices. To exert their function, mature osteoclasts maintain the cellular polarity and directional vesicle trafficking to and from the resorbing bone surface. However, the regulatory mechanisms an
Externí odkaz:
https://doaj.org/article/dccf3fbc05964da5941a3b4688ff3648
Autor:
Kohei Fujiwara, Masashi Maekawa, Yuki Iimori, Akane Ogawa, Takeshi Urano, Nobuaki Kono, Hiroyuki Takeda, Shigeki Higashiyama, Makoto Arita, Junko Murai
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108529- (2023)
Summary: Schlafen (SLFN) 11 enhances cellular sensitivity to various DNA-damaging anticancer agents. Among the human SLFNs (SLFN5/11/12/13/14), SLFN11 is unique in its drug sensitivity and ability to block replication under DNA damage. In biochemical
Externí odkaz:
https://doaj.org/article/4c15fe539cfc4f56bec45ef141dc2f8a
Autor:
Yusuke Hayashi, Jun Nakayama, Mizuki Yamamoto, Masashi Maekawa, Shinya Watanabe, Shigeki Higashiyama, Jun-ichiro Inoue, Yusuke Yamamoto, Kentaro Semba
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background In vivo investigations with cancer cells have powerful tools to discover cancer progression mechanisms and preclinical candidate drugs. Among these in vivo experimental models, the establishment of highly malignancy cell lines wit
Externí odkaz:
https://doaj.org/article/49c64eebe1bf4dc281eb06637093e2ad
Autor:
Masashi Kuriyama, Hisaaki Hirose, Toshihiro Masuda, Masachika Shudou, Jan Vincent Arafiles, Miki Imanishi, Masashi Maekawa, Yuji Hara, Shiroh Futaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Macropinocytosis is a type of endocytosis accompanied by actin rearrangement-driven membrane deformation, such as lamellipodia formation and membrane ruffling, followed by the formation of large vesicles, macropinosomes. Ras-transformed canc
Externí odkaz:
https://doaj.org/article/65594343af224a928945ab399d8ff527
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Macropinocytosis is a unique type of endocytosis accompanied by membrane ruffle formation. Closure of membrane ruffles leads to the uptake of large volumes of fluid phase and, subsequently, the formation of large vacuoles termed macropinosomes. Immun
Externí odkaz:
https://doaj.org/article/ba1781388cb346eb9856f1917b2e15a1
Autor:
Nanami Ueda, Masashi Maekawa, Tsubasa S. Matsui, Shinji Deguchi, Tomoyo Takata, Jun Katahira, Shigeki Higashiyama, Miki Hieda
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The linker of nucleoskeleton and cytoskeleton (LINC) complex is composed of the inner nuclear membrane-spanning SUN proteins and the outer nuclear membrane-spanning nesprin proteins. The LINC complex physically connects the nucleus and plasma membran
Externí odkaz:
https://doaj.org/article/15fb16ce55f94ddb8c46950153f26deb
Autor:
Masashi Kuriyama, Hisaaki Hirose, Toshihiro Masuda, Masachika Shudou, Jan Vincent V. Arafiles, Miki Imanishi, Masashi Maekawa, Yuji Hara, Shiroh Futaki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c2b128eeac154be18a9f286cef64caaa
Autor:
Masashi Maekawa, Kazufumi Tanigawa, Tomohisa Sakaue, Hiromi Hiyoshi, Eiji Kubota, Takashi Joh, Yuji Watanabe, Tomohiko Taguchi, Shigeki Higashiyama
Publikováno v:
Biology Open, Vol 6, Iss 11, Pp 1707-1719 (2017)
Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is related to numerous pathophysiological events. We previously reported that a RING ubiquitin ligase complex scaffold protein, cullin-3 (CUL3), and one of its adapto
Externí odkaz:
https://doaj.org/article/c859adc1848644b293d58a09caee2ce5
Autor:
Takashi Hirama, Stella M. Lu, Jason G. Kay, Masashi Maekawa, Michael M. Kozlov, Sergio Grinstein, Gregory D. Fairn
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The plasma membrane is enriched in phosphatidylserine (PtdSer) mostly localized at the inner leaflet, which is predicted to induce membrane curvature. Here the authors show that membrane curvature induced by the proximity of anionic phospholipids can
Externí odkaz:
https://doaj.org/article/1c22c972acee4860ae917618ded44d94
Autor:
Masashi Maekawa
Publikováno v:
Sensors, Vol 17, Iss 3, p 504 (2017)
The cellular membrane of eukaryotes consists of phospholipids, sphingolipids, cholesterol and membrane proteins. Among them, cholesterol is crucial for various cellular events (e.g., signaling, viral/bacterial infection, and membrane trafficking) in
Externí odkaz:
https://doaj.org/article/07ca239c953646eba2993a00a8bff197