Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Masashi Imanishi"'
Autor:
Minh H. Nguyen, Masashi Imanishi, Taichi Kurogi, Xuemei Wan, Kerry L. McPhail, Amos B. Smith, Jane E. Ishmael
Publikováno v:
The Journal of Organic Chemistry. 83:4287-4306
The mandelalides comprise a family of structurally complex marine macrolides that display significant cytotoxicity against several human cancer cell lines. Presented here is a full account on the development of an Anion Relay Chemistry (ARC) strategy
Publikováno v:
Journal of the American Chemical Society
Anion relay chemistry (ARC), an effective, multicomponent union tactic, was successfully employed for the total synthesis of the highly cytotoxic marine macrolide (−)-mandelalide A (1). The northern hemisphere was constructed via a new type II ARC/
Publikováno v:
Scopus-Elsevier
Odor gas detection is important for the detection of explosives, environmental sensing, biometrics, foodstuffs and a comfortable life. Such odor-source localizations is an active research area for robotics. In this study, we tried to detect odor chem
Autor:
Kenichi Washizuka, Yasuhiro Matsumura, Yasuyo Tomishima, Keiko Nakano, Naoko Unami, Fujiko Takamura, Takanobu Araki, Shigeo Matsui, Minoru Sakurai, Masashi Imanishi, Takao Yamamoto, Kaori Hamada, Kouji Hattori, Hitoshi Hamashima, Nobuhiro Yamamoto, Emiko Imamura, Hirofumi Ishikawa, Koji Ueshima, Yutaka Nakajima, Susumu Toda, Shinji Itou
Publikováno v:
Journal of Medicinal Chemistry. 52:3063-3072
As an extension of research conducted on beta(3)-adrenergic receptor agonists as potential drugs for treating overactive bladder (OAB), novel series containing an acylsulfonamide moiety instead of the carboxylic acid moiety were evaluated. These comp
Autor:
Masashi, Imanishi, Yasuyo, Tomishima, Shinji, Itou, Hitoshi, Hamashima, Yutaka, Nakajima, Kenichi, Washizuka, Minoru, Sakurai, Shigeo, Matsui, Emiko, Imamura, Koji, Ueshima, Takao, Yamamoto, Nobuhiro, Yamamoto, Hirofumi, Ishikawa, Keiko, Nakano, Naoko, Unami, Kaori, Hamada, Yasuhiro, Matsumura, Fujiko, Takamura, Kouji, Hattori
Publikováno v:
Journal of Medicinal Chemistry. 51:1925-1944
A novel class of biphenyl analogues containing a benzoic acid moiety based on lead compound 8i have been identified as potent and selective human beta 3 adrenergic receptor (beta 3-AR) agonists with good oral bioavailability and long plasma half-life
Autor:
Shuji Akai, Yasuyuki Kita, Masato Matsugi, Masashi Imanishi, Sohei Omura, Yasushi Takebe, Tadaatsu Naka, Kouichi Tanimoto
Publikováno v:
Chemistry - A European Journal. 8:4255-4264
The first lipase-catalyzed domino reaction is described in which the acyl moiety formed during the enzymatic kinetic resolution of furfuryl alcohols (+/-)-3 with a 1-ethoxyvinyl ester 2 was utilized as a part of the constituent structure for the subs
Autor:
Nguyen, Minh H., Masashi Imanishi, Taichi Kurogi, Xuemei Wan, Ishmael, Jane E., McPhail, Kerry L., Smith III, Amos B.
Publikováno v:
Journal of Organic Chemistry; 4/20/2018, Vol. 83 Issue 8, p4287-4306, 20p
Autor:
Masashi Imanishi, Kouji Hattori
Publikováno v:
ChemInform. 43
Publikováno v:
ChemInform. 29
Autor:
Naoko Unami, Minoru Sakurai, Keiko Nakano, Shinji Itou, Kenichi Washizuka, Shigeo Matsui, Kaori Hamada, Yasuhiro Matsumura, Kouji Hattori, Koji Ueshima, Takanobu Araki, Masashi Imanishi, Daisuke Tanabe, Emiko Imamura, Hirofumi Ishikawa, Susumu Toda, Masaya Orita, Yutaka Nakajima, Takao Yamamoto, Fujiko Takamura, Nobuhiro Yamamoto
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(16)
As an extension of research, we have investigated modification of left-hand side (LHS) of biphenyl analogues containing an acylsulfonamide moiety in the development of potent and selective human beta(3)-adrenergic receptor (AR) agonists. Result of st