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pro vyhledávání: '"Masashi Hisaoka"'
Autor:
Shinichi Miura, Mitsuhashi Yoshihiro, Kazuo Tanaka, Shinichi Kurakata, Takahiro Shibayama, Fumie Tanzawa, Akihiro Tomida, Tatsuji Nomura, Kenji Hanaoka, Takashi Tsuruo, Akira Matsuda, Yusuke Wataya, Masako Suzuki, Tomowo Kobayashi, Kaneko Masakatsu, Haruo Iwabuchi, Tomoko Ikeda, Akihiko Nakagawa, Masashi Hisaoka, Takuma Sasaki
Publikováno v:
International Journal of Cancer. 82:226-236
We have studied the antitumor activity and the novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-β-d-arabino-pentofuranosyl)cytosine) and its N4-palmitoyl derivative (CS-682). In vitro, CS-682 showed strong cytotoxicity against