Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Masashi Fukuoka"'
Autor:
Masashi Fukuoka, Hiromi Fujita, Kosumo Numao, Yasuko Nakamura, Hideo Shimizu, Masayuki Sekiguchi, Hirohiko Hohjoh
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Fukuoka et al. investigate the possible role of miR-199-3p during aging, which significantly decreases in the blood of aged mice compared to young mice. They also show that miR-199-3p enhance muscle regeneration, and administering miR-199 mimics to m
Externí odkaz:
https://doaj.org/article/8bbe8e8563d9448996b481d9af3377be
Autor:
Masashi Fukuoka, Masaki Takahashi, Hiromi Fujita, Tomoko Chiyo, H. Akiko Popiel, Shoko Watanabe, Hirokazu Furuya, Miho Murata, Keiji Wada, Takashi Okada, Yoshitaka Nagai, Hirohiko Hohjoh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 79-90 (2018)
Huntington’s disease (HD) is an intractable neurodegenerative disorder caused by mutant Huntingtin (HTT) proteins that adversely affect various biomolecules and genes. MicroRNAs (miRNAs), which are functional small non-coding RNAs, are also affecte
Externí odkaz:
https://doaj.org/article/223f3142b53e4d84b5a0fd79dddaa324
Autor:
Kimitoshi Kimura, Hirohiko Hohjoh, Masashi Fukuoka, Wakiro Sato, Shinji Oki, Chiharu Tomi, Hiromi Yamaguchi, Takayuki Kondo, Ryosuke Takahashi, Takashi Yamamura
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
MiRNAs are small RNA molecules that can regulate gene expression. Here the authors show that expression of several exosomal miRNAs are altered in patients with multiple sclerosis, and that let-7i modulates regulatory T cell homeostasis to contribute
Externí odkaz:
https://doaj.org/article/39030d68cecb4083837a09a44d6cae96
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201796 (2018)
Gefitinib and erlotinib are epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs). Although EGFR-TKIs are effective as anti-cancer drugs, cancer cells sometimes gain tolerance to the drugs. Previous studies suggested that the fibrob
Externí odkaz:
https://doaj.org/article/0129d495ea504abfbfd71edba0a341ed
Autor:
Masaki Takahashi, Mari Suzuki, Masashi Fukuoka, Nobuhiro Fujikake, Shoko Watanabe, Miho Murata, Keiji Wada, Yoshitaka Nagai, Hirohiko Hohjoh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
The α-synuclein (SNCA) gene is a responsible gene for Parkinson's disease (PD); and not only nucleotide variations but also overexpression of SNCA appears to be involved in the pathogenesis of PD. A specific inhibition against mutant SNCA genes carr
Externí odkaz:
https://doaj.org/article/030157d24a6d49bd8bc61a8092bb136f
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103130 (2014)
Heat shock, sudden change in temperature, triggers various responses in cells for protecting the cells from such a severe circumstance. Here we investigated gene silencing mediated by endogenous microRNAs (miRNAs) in mammalian cells exposed to a mild
Externí odkaz:
https://doaj.org/article/417985a568014928bad3dfca980c26fa
Publikováno v:
Rock Mechanics and Engineering Geology in Volcanic Fields ISBN: 9781003293590
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff9ade1bba80bf2fc19d7810500ab502
https://doi.org/10.1201/9781003293590-19
https://doi.org/10.1201/9781003293590-19
Autor:
Masashi Fukuoka, Naoya Sugimoto, Misa Kaji, Yuki Aanzai, Hirohiko Hohjoh, Lila Otani, Huijuan Jia, Moe Miyoshi, Hisanori Kato, Yasuhisa Imakado, Tetsuo Murakami
Publikováno v:
Food Science & Nutrition, Vol 9, Iss 3, Pp 1452-1459 (2021)
Food Science & Nutrition
Food Science & Nutrition
Scope We previously demonstrated that protein restriction in utero induced salt‐sensitive hypertension and changed renal levels of angiotensin type 2 receptor (AT2R) in Stroke‐Prone Spontaneously Hypertensive Rat (SHRSP). Here, we investigated if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b889cd2942212279d10ec45444e7789
https://doaj.org/article/f4c74f8b64434dc7b1b3077cf6a91443
https://doaj.org/article/f4c74f8b64434dc7b1b3077cf6a91443
Autor:
Masashi Fukuoka, Keiko Yoshida, Sayaka Ishii, Yuta Yatsuo, Shu Ichiro Kashiwaba, Takuma Naraoka, Yasufumi Murakami, Hiroki Kazama
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8493, p 8493 (2020)
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8493, p 8493 (2020)
Cell division is essential for the maintenance of life and involves chromosome segregation and subsequent cytokinesis. The processes are tightly regulated at both the spatial and temporal level by various genes, and failures in this regulation are as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efeac24b9943b9ae91966dfba9432dd3
Autor:
Yasuko Nakamura, Hirohiko Hohjoh, Kosumo Numao, Masayuki Sekiguchi, Masashi Fukuoka, Hideo Shimizu, Hiromi Fujita
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Parabiosis experiments suggest that molecular factors related to rejuvenation and aging circulate in the blood. Here, we show that miR-199-3p, which circulates in the blood as a cell-free miRNA, is significantly decreased in the blood of aged mice co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811211101137a5ccab7da00c93ebeceb
https://pubmed.ncbi.nlm.nih.gov/33782502
https://pubmed.ncbi.nlm.nih.gov/33782502