Zobrazeno 1 - 10
of 625
pro vyhledávání: '"Masashi Aoki"'
Autor:
Shun Yoshida, Takafumi Hasegawa, Takaaki Nakamura, Kazuki Sato, Naoto Sugeno, Shun Ishiyama, Kiyotoshi Sekiguchi, Muneshige Tobita, Atsushi Takeda, Masashi Aoki
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Since the identification of vacuolar protein sorting (VPS) 35, as a causative molecule for familial Parkinson’s disease (PD), retromer-mediated endosomal machinery has been a rising factor in the pathogenesis of the disease. The retromer c
Externí odkaz:
https://doaj.org/article/6f9f6bbeb9224731973eaf8ff56f8bcc
Autor:
Kazutoshi Konomatsu, Yosuke Kakisaka, Shiho Sato, Takafumi Kubota, Temma Soga, Kazushi Ukishiro, Kazutaka Jin, Shunji Mugikura, Masashi Aoki, Nobukazu Nakasato
Publikováno v:
Radiology Case Reports, Vol 19, Iss 5, Pp 2058-2061 (2024)
Lipoma of the corpus callosum, also known as pericallosal lipoma, is a rare congenital brain abnormality associated with corpus callosum dysgenesis or agenesis. Two morphological types are described: tubulonodular and curvilinear, with the latter bei
Externí odkaz:
https://doaj.org/article/38d249c9064d47ef993853d2faedfcae
Autor:
Satoshi Yamashita, Yuji Takahashi, Jun Hashimoto, Ayuka Murakami, Ryoichi Nakamura, Masahisa Katsuno, Rumiko Izumi, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, the Japan MSP Study Group
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 938-945 (2024)
Abstract Objective Multisystem proteinopathy (MSP) is an inherited disorder in which protein aggregates with TAR DNA‐binding protein of 43 kDa form in multiple organs. Mutations in VCP, HNRNPA2B1, HNRNPA1, SQSTM1, MATR3, and ANXA11 are causative fo
Externí odkaz:
https://doaj.org/article/29bf1618d9b14056839855df94bc3493
Autor:
Rumiko Izumi, Kensuke Ikeda, Tetsuya Niihori, Naoki Suzuki, Matsuyuki Shirota, Ryo Funayama, Keiko Nakayama, Hitoshi Warita, Maki Tateyama, Yoko Aoki, Masashi Aoki
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 577-592 (2024)
Abstract Objective Multisystem proteinopathy type 3 (MSP3) is an inherited, pleiotropic degenerative disorder caused by a mutation in heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1), which can affect the muscle, bone, and/or nervous system. This
Externí odkaz:
https://doaj.org/article/9c37292f249446f1a8c4290b97fe408c
Autor:
Shuhei Nishiyama, Jin Myong Seok, Amy E. Wright, Itay Lotan, Takahisa Mikami, Natalia C. Drosu, Natasha Bobrowski-Khoury, Monique R. Anderson, Philippe A. Bilodeau, Patrick Schindler, Friedemann Paul, Masashi Aoki, Michael R. Yeaman, Michael Levy, The Guthy-Jackson Charitable Foundation CIRCLES Study Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Proinflammatory cytokines, such as (IL: interleukin) IL-6 and IL-17A, and complement fixation are critical in the immunopathogenesis of neuromyelitis optica spectrum disorders (NMOSD). Blocking the IL-6 receptor or the C5 complement pathway
Externí odkaz:
https://doaj.org/article/aedaf31a7f7349ebb6c22664c55bd90c
Autor:
Chihiro Namatame, Yoichiro Abe, Yoshiki Miyasaka, Yoshiki Takai, Yuki Matsumoto, Toshiyuki Takahashi, Tomoji Mashimo, Tatsuro Misu, Kazuo Fujihara, Masato Yasui, Masashi Aoki
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8169 (2024)
Conventional rodent neuromyelitis optica spectrum disorder (NMOSD) models using patient-derived immunoglobulin G (IgG) are potentially affected by the differences between the human and rodent aquaporin-4 (AQP4) extracellular domains (ECDs). We hypoth
Externí odkaz:
https://doaj.org/article/c5b569515a6744dba00b577ec6478122
Autor:
Naoki Suzuki, Makoto Kanzaki, Masashi Koide, Rumiko Izumi, Ryo Fujita, Tadahisa Takahashi, Kazumi Ogawa, Yutaka Yabe, Masahiro Tsuchiya, Masako Suzuki, Ryuhei Harada, Akiyuki Ohno, Hiroya Ono, Naoko Nakamura, Kensuke Ikeda, Hitoshi Warita, Shion Osana, Yoshitsugu Oikawa, Takafumi Toyohara, Takaaki Abe, Muliang Rui, Satoru Ebihara, Ryoichi Nagatomi, Yoshihiro Hagiwara, Masashi Aoki
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0306021 (2024)
Sporadic inclusion body myositis (sIBM) is a muscle disease in older people and is characterized by inflammatory cell invasion into intact muscle fibers and rimmed vacuoles. The pathomechanism of sIBM is not fully elucidated yet, and controversy exis
Externí odkaz:
https://doaj.org/article/f7dc538e6a104a57b7266fa9a8d4f046
Autor:
Madoka Mori-Yoshimura, Naoki Suzuki, Masahisa Katsuno, Masanori P. Takahashi, Satoshi Yamashita, Yasushi Oya, Atsushi Hashizume, Shinichiro Yamada, Masayuki Nakamori, Rumiko Izumi, Masaaki Kato, Hitoshi Warita, Maki Tateyama, Hiroshi Kuroda, Ryuta Asada, Takuhiro Yamaguchi, Ichizo Nishino, Masashi Aoki
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background A rare muscle disease, GNE myopathy is caused by mutations in the GNE gene involved in sialic acid biosynthesis. Our recent phase II/III study has indicated that oral administration of aceneuramic acid to patients slows disease pr
Externí odkaz:
https://doaj.org/article/6628f652b5c34969bbb20872f77b28fa
Autor:
Tetsuya Akaishi, Tatsuro Misu, Kazuo Fujihara, Kumi Nakaya, Naoki Nakaya, Tomohiro Nakamura, Mana Kogure, Rieko Hatanaka, Fumi Itabashi, Ikumi Kanno, Kimihiko Kaneko, Toshiyuki Takahashi, Juichi Fujimori, Yoshiki Takai, Shuhei Nishiyama, Tadashi Ishii, Masashi Aoki, Ichiro Nakashima, Atsushi Hozawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract White blood cell (WBC) count profiles in anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD) and anti-myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are still unknown. This study ev
Externí odkaz:
https://doaj.org/article/7008886e2ba74a87a069dffcecd429d7
Autor:
Naoya Yamazaki, Takafumi Hasegawa, Kensuke Ikeda, Ako Miyata, Shin-ichiro Osawa, Kuniyasu Niizuma, Shigenori Kanno, Teiji Tominaga, Masashi Aoki
Publikováno v:
Case Reports in Neurology, Vol 15, Iss 1, Pp 41-47 (2023)
Disturbance of smell is often accompanied with common neurodegenerative diseases such as Parkinson’s and Alzheimer’s diseases. In addition, patients with head trauma, intracranial tumors, and hydrocephalus can also develop olfactory dysfunction,
Externí odkaz:
https://doaj.org/article/dfbfee03a3d64404bdfbc2c774fb23d7