Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Masashi, Kawami"'
Publikováno v:
Biocell. 2022, Vol. 46 Issue 8, p1861-1865. 5p.
Publikováno v:
Molecules, Vol 27, Iss 15, p 4889 (2022)
Molecular interaction analysis is an essential technique for the study of biomolecular functions and the development of new drugs. Most current methods generally require manipulation to immobilize or label molecules, and require advance identificatio
Externí odkaz:
https://doaj.org/article/f3a61e19f2e34be3a5a46ca34f068f4b
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 23 (2020)
Background: Drug-induced lung injury leads to serious lung diseases, such as pulmonary fibrosis. We demonstrated in an alveolar epithelial cell line A549/ABCA3 that certain microRNAs were associated with bleomycin induced epithelial-mesenchymal trans
Externí odkaz:
https://doaj.org/article/1a487b0d0bd94fa4a680bcc7518adf84
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1853 (2021)
Background: Epithelial–mesenchymal transition (EMT), a phenotypic conversion of the epithelial to mesenchymal state, contributes to cancer progression. Currently, several microRNAs (miRNAs) are associated with EMT-mediated cancer progression, but t
Externí odkaz:
https://doaj.org/article/7475a45059224d86bb6729c12ddea4d4
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:1069-1076
Methotrexate (MTX) is known to induce serious lung diseases, such as pulmonary fibrosis. Although we demonstrated that MTX is associated with epithelial-mesenchymal transition (EMT), the underlying mechanism remains unclear. Nuclear factor erythroid
Autor:
Ayano Yamamoto, Masashi Kawami, Takashi Konaka, Shinnosuke Takenaka, Ryoko Yumoto, Mikihisa Takano
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
PURPOSE. Several anticancer drugs including bleomycin (BLM) and methotrexate (MTX) cause serious lung diseases such as pulmonary fibrosis. Although evidences showing the association of epithelial-mesenchymal transition (EMT) with pulmonary fibrosis a
Externí odkaz:
https://doaj.org/article/3f47cb94e09f4061b1e3605cbd1fb3d1
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 21, Iss 1 (2018)
Purpose. Alveolar clearance of proteins, such as albumin, plays an essential role in recovery from lung injuries. Albumin is known to be oxidized by reactive oxygen species (ROS), leading to generation of advanced oxidation protein products (AOPP)-al
Externí odkaz:
https://doaj.org/article/a0c32825f1f441539596f91618b0a24b
Publikováno v:
Chemical and Pharmaceutical Bulletin. 69:407-410
Hydantoins, including the antiepileptic drug phenytoin, contain an amide nitrogen and an imide nitrogen, both of which can be alkylated. However, due to the higher acidity of its proton, N3 can be more easily alkylated than N1 under basic conditions.
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:522-526
Quercetin is a flavonol that is known to have numerous beneficial biological effects such as an anti-fibrotic effect. Epithelial-mesenchymal transition (EMT) of alveolar type II epithelial cells is one of major causes of pulmonary fibrosis. However,
Publikováno v:
Biologicalpharmaceutical bulletin. 45(2)
In the lung alveolar region, the innate immune system serves as an important host defense system. We recently reported that peptide transporter 2 (PEPT2) has an essential role in the uptake of bacterial peptides and induction of innate immune respons