Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Masashi, Hirata"'
Autor:
Munetaka Hirose, Mayumi Takatori, Yoshihiro Kuroda, Mineo Abe, Eri Murata, Tetsuro Isada, Koyo Ueda, Kenji Shigemi, Masayuki Shibazaki, Fumihiro Shimizu, Masashi Hirata, Keita Fukazawa, Masahiro Sakaguchi, Kyoko Kageyama, Yoshifumi Tanaka
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 107-113 (2008)
As TrkA, a high-affinity receptor of nerve growth factor (NGF), is a potential target for relieving uncontrolled inflammatory pain, an effective inhibitor of TrkA has been required for pain management. To identify a specific inhibitor of TrkA activit
Externí odkaz:
https://doaj.org/article/d04a07ba24bd4304b386a5f1d1ccf85f
Publikováno v:
Molecular Simulation. 38:481-490
Molecular dynamics simulation was performed to analyse the phenomena of replacement of methane hydrate with carbon dioxide (CO2) at 270 K and 5.0 MPa for 5300 ps. The methane hydrate phase was constructed with 16 unit cells of hydrate. Every cage in
Autor:
Yoshio Iwai, Masashi Hirata
Publikováno v:
Molecular Simulation. 38:333-340
The binary structure II hydrogen–tetrahydrofuran (THF) hydrate was studied with molecular dynamics simulation. The simulations were carried out at 300, 310 K and 10.1 MPa, and with various contents of hydrogen and THF. The migrations of hydrogen mo
Publikováno v:
Procedia Engineering. 10:112-117
The roles of grain boundary microstructure in fatigue crack propagation during cyclic deformation were investigated in order to evidence the utility of grain boundary engineering for control of fatigue crack propagation in SUS304 austenitic stainless
Autor:
Keita Fukazawa, Eri Murata, Yoshifumi Tanaka, Yoko Okayama, Munetaka Hirose, Kenji Shigemi, Satoshi Taniguchi, Mayumi Takatori, Tetsuro Isada, Mayumi Tani, Masashi Hirata
Publikováno v:
The Journal of Physiological Sciences. 57:321-325
Hyperbaric exposure induces lesions of the CNS in scuba divers. Repeated exposures to hyperbaric air at 0.5 MPa for 30 min with short intervals suppressed NGF-stimulated neurite outgrowth, concomitant with a decrease in the protein expression of ERK
Publikováno v:
Developmental Dynamics. 234:293-300
The orderly pigment pattern of zebrafish (Danio rerio) is a good model system for studying how spatial patterns form in animals. Recent molecular genetic studies have shown that interactions between the pigment cells play major roles in pattern forma
Autor:
Kyoko Kageyama, Masahiro Sakaguchi, Chikako Mochida, Munetaka Hirose, Yoshihiro Kuroda, Masashi Hirata, Chie Sotozono
Publikováno v:
Anesthesiology. 100:1206-1210
Background Although lidocaine is recognized as an excellent topical corneal analgesic, its toxic effect on corneal epithelial cells limits its use during corneal epithelial wound healing. Mechanism of the impairment of corneal reepithelialization wit
Autor:
Masahiro Sakaguchi, Terumichi Nakagawa, Masashi Hirata, Munetaka Hirose, Yoshifumi Tanaka, Shinichi Sawa, Yoshihiro Kuroda
Publikováno v:
British Journal of Pharmacology. 142:222-228
1. Acetyl-KIFMK-amide (KIFMK) restores fast inactivation to mutant sodium channels having a defective inactivation gate. Its binding site with sodium channels could be considered to be the cytoplasmic linker (III-IV linker) connecting domains III and
Publikováno v:
Developmental Dynamics. 227:497-503
Zebrafish have a characteristic horizontal-stripe pigment pattern made by a specific distribution of three types of pigment cells: melanophores, xanthophores, and iridophores. This pattern is a valuable model to investigate how the spatial patterns f
Autor:
Syozo Hioki, Hiroto Shoji, Masashi Hirata, Shigeru Kondo, Tsuyoshi Watanabe, Yoh Iwasa, Atsushi Mochizuki
Publikováno v:
Developmental Dynamics. 226:627-633
The formation of stripe patterns in animal skin has been explained by the reaction-diffusion (RD) system, a hypothetical chemical reaction proposed by A. Turing. Although animal stripes usually have directionality, the RD model alone cannot explain h