Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Masaru Uyeda"'
Autor:
Masaru Uyeda, Tomonori Iijima, Hideo Hachiyanagi, Naoko Yamamoto, Yutaka Kido, Teruo Tanaka, Kazuo Takahama
Publikováno v:
Journal of Health Science. 55:625-630
Two pure cultures (strains No. A-11 and A-12) from soil sample capable of utilizing aniline as the sole source of nitrogen and energy were regarded as Achromobacter sp and Pseudomonas sp, respectively. Degradation patterns of aniline and aniline deri
Publikováno v:
Journal of International Medical Research. 33:178-187
We tested the antimicrobial activity of orthophthalaldehyde (OPA) against 21 strains (16 species) of pathogenic microorganisms that cause hospital-associated infections. Changes in hepatitis B surface antigen (HBs-Ag) resulting from the addition of O
Autor:
Kazuya Matsuda, Masami Otsuka, Masaru Uyeda, Tadashi Okawara, Mohamed Abdel-Aziz, Keitarou Suzuki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1669-1672
o-, m-, p-Phenylenediamines having 2,3,4-trihydroxy, 3,4 dihydroxy, and 4-hydroxybenzoyl moieties were prepared and their inhibitory activities were measured against topoisomerase I and II. More hydroxy groups on two aromatic rings increased the acti
Autor:
Masaru Uyeda
Publikováno v:
YAKUGAKU ZASSHI. 124:469-479
In 1995, we discovered new antiherpetic antibiotics, called fattiviracins. The producing organism was classified as a strain belonging to Streptomyces microflavus. The strain produced at least 13 fattiviracin derivatives (FV-1 to FV-13). Fattiviracin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 18:497-503
A novel inhibitor of topoisomerase II designated as 2070-DTI was isolated from the culture filtrate of Streptomyces sp. strain No. 2070. The structure was determined to be that of the known soyasaponin I on the basis of spectroscopic methods (NMR and
Autor:
Masaru UYEDA
Publikováno v:
Kagaku To Seibutsu. 40:230-235
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 65:861-864
Streptomyces microflavus strain No. 2445 produces many derivatives of fattiviracin antibiotics. The major product of these derivatives is fattiviracin FV-8, which consists of four glucose and two trihydroxy fatty acid residues. We found that this str
Publikováno v:
Journal of Enzyme Inhibition. 15:357-366
The inhibitory effects of various fatty acids on topoisomerases were examined, and their structure activity relationships and mechanism of action were studied. Saturated fatty acids (C6:0 to C22:0) did not inhibit topoisomerase I, but cis-unsaturated
Publikováno v:
The Journal of Antibiotics. 51:991-998
A novel inhibitor of topoisomerases designated as topostatin was isolated from the culture filtrate of Thermomonospora alba strain No. 1520. Topostatin inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I, and also inhibi
Publikováno v:
Journal of Enzyme Inhibition. 14:69-83
A novel inhibitor of topoisomerases designated as Macrostatin has been isolated from the culture filtrate of Streptomyces avermitilis strain No. C-127 and purified by successive chromatography on Dowex, activated charcoal, gel filtration and cellulos