Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Masaru Ueno"'
Autor:
Masaru Ueno
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 370 (2023)
The regulation of telomere length has a significant impact on cancer risk and aging in humans. Circular chromosomes are found in humans and are often unstable during mitosis, resulting in genome instability. Some types of cancer have a high frequency
Externí odkaz:
https://doaj.org/article/44c201fcb8b14a859b68566ff563b924
Autor:
Parvaneh Emami, Masaru Ueno
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
3,3’-Diindolylmethane (DIM) is a compound derived from the digestion of indole-3-carbinol, found in the broccoli family. It induces apoptosis and autophagy in some types of human cancer. DIM extends lifespan in the fission yeast Schizosaccharomyces
Externí odkaz:
https://doaj.org/article/cb2e688aa2a846bc89a95617bfd026c7
Autor:
Chiaki Fujiwara, Yukiko Muramatsu, Megumi Nishii, Kazuhiro Tokunaka, Hidetoshi Tahara, Masaru Ueno, Takao Yamori, Yoshikazu Sugimoto, Hiroyuki Seimiya
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Telomere maintenance by telomerase activity supports the infinite growth of cancer cells. MST-312, a synthetic telomerase inhibitor, gradually shortens telomeres at non-acute lethal doses and eventually induces senescence and apoptosis of te
Externí odkaz:
https://doaj.org/article/bcff0d57a37a40e7bac59241a17f8c5f
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190523 (2018)
Ring chromosomes are circular chromosomal abnormalities that have been reported in association with some genetic disorders and cancers. In Schizosaccharomyces pombe, lack of function of protection of telomere 1 (Pot1) or telomerase catalytic subunit
Externí odkaz:
https://doaj.org/article/48481e153a024a1fa00b1e58d36498f6
Autor:
Hossain Mohammad Shamim, Yukako Minami, Daiki Tanaka, Shinobu Ukimori, Johanne M Murray, Masaru Ueno
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187775 (2017)
Thymidine kinase converts 5-fluorodeoxyuridine to 5-fluorodeoxyuridine monophosphate, which causes disruption of deoxynucleotide triphosphate ratios. The fission yeast Schizosaccharomyces pombe does not express endogenous thymidine kinase but 5-fluor
Externí odkaz:
https://doaj.org/article/cacdc72e7f3f498c96e62858d6fdebea
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 4, Iss 4, Pp 562-575 (2009)
To evaluate motions and joint reaction forces of the total knee prosthesis during deep knee flexion such as kneeling and sitting straight, a simulator that reproduces the passive motion of the knee has been developed. The main feature of the simulato
Externí odkaz:
https://doaj.org/article/9d1e9cdc152946f28429d9845079a1cb
Autor:
Tomoko Nanbu, Luân C Nguyễn, Ahmed G K Habib, Naoya Hirata, Shinobu Ukimori, Daiki Tanaka, Kenta Masuda, Katsunori Takahashi, Masashi Yukawa, Eiko Tsuchiya, Masaru Ueno
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140456 (2015)
The uncapping of telomeres induces a DNA damage response. In Schizosaccharomyces pombe, deletion of pot1+ causes telomere uncapping and rapid telomere resection, resulting in chromosome fusion. Using the nmt-pot1-aid strain, we previously reported th
Externí odkaz:
https://doaj.org/article/4bcc363bd672429c834725231787d1f1
Autor:
Yuko Imamura, Feifei Yu, Misaki Nakamura, Yuhki Chihara, Kyo Okane, Masahiro Sato, Muneyoshi Kanai, Ryoko Hamada, Masaru Ueno, Masashi Yukawa, Eiko Tsuchiya
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130397 (2015)
RSC (Remodel the Structure of Chromatin) is an ATP-dependent chromatin remodeling complex essential for the growth of Saccharomyces cerevisiae. RSC exists as two distinct isoforms that share core subunits including the ATPase subunit Nps1/Sth1 but co
Externí odkaz:
https://doaj.org/article/e9363626bfe44a50bfd456d6a4a5cf41
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97774 (2014)
Ergothioneine is a small, sulfur-containing metabolite (229 Da) synthesized by various species of bacteria and fungi, which can accumulate to millimolar levels in tissues or cells (e.g. erythrocytes) of higher eukaryotes. It is commonly marketed as a
Externí odkaz:
https://doaj.org/article/03f086cad2684650a0fa21462d77c54a
Autor:
Maiko Hirai, Hiroshi Yagasaki, Koji Kanezawa, Masaru Ueno, Katsuyoshi Shimozawa, Kohsuke Imai, Tomohiro Morio, Motohiro Kato, Yoshihiro Gocho, Satoshi Narumi, Yasuhiro Ebihara, Ichiro Morioka
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:e290-e293