Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Masaru Ken Shiratori"'
Autor:
Peggy Ko, Dejin Zhan, Brad Snedecor, Mark Sanford, Amy Shen, Masaru Ken Shiratori, Shahram Misaghi, Mandy Yim, Joni Tsukuda, Michael W. Laird, Zhilan Hu, David E. Shaw
Publikováno v:
Biotechnology Progress. 34:624-634
In the past few decades, a large variety of therapeutic antibodies and proteins have been expressed in Chinese hamster ovary (CHO) cells. This mammalian expression system is robust, scalable, relatively inexpensive, and importantly allows for post-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ff9f6029f4fd2377a3413a48b2b52d
https://doi.org/10.1002/btpr.2594
https://doi.org/10.1002/btpr.2594
Autor:
Masaru Ken Shiratori, Robert Kiss
Publikováno v:
New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins ISBN: 9783319971087
Industrial-scale mammalian cell culture processes have been contaminated by viruses during the culturing phase. Although the historical frequency of such events has been quite low, the impact of contamination can be significant for the manufacturing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcdb33b6f714ce28334401fee0f013ee
https://doi.org/10.1007/10_2017_38
https://doi.org/10.1007/10_2017_38
Autor:
Masaru Ken Shiratori, Eric Fallon, Justin Bourret, Steven J. Meier, Salim Charaniya, Mahalia Corrales, Robert Kiss, Michael Pohlscheidt, Fikret Kulenovic
Publikováno v:
Applied Microbiology and Biotechnology. 98:2965-2971
The production of therapeutic proteins by mammalian cell culture is complex and sets high requirements for process, facility, and equipment design, as well as rigorous regulatory and quality standards. One particular point of concern and significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a970ee20b9e9e5999067938cfefebb6c
https://doi.org/10.1007/s00253-013-5451-3
https://doi.org/10.1007/s00253-013-5451-3
Autor:
Wendy Hsu, Jordan Baker, Jayashree Subramanian, Brad Snedecor, Danming Tang, Benjamin Haley, Peter Liu, Shahram Misaghi, Wendy Sandoval, Masaru Ken Shiratori, Lucas Luo, Michael W. Laird
Publikováno v:
Biotechnology Journal. 14:1800332
Chinese hamster ovary (CHO) cell lines are used to express a variety of therapeutic proteins. However, lactogenic behavior displayed by some CHO cell lines during manufacturing processes may result in a decline in viability, productivity, and possibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51895c59a15ec8c9afde118e1043fed
https://doi.org/10.1002/biot.201800332
https://doi.org/10.1002/biot.201800332
Autor:
Aaron Chen, Natarajan Vijayasankaran, Feng Li, Masaru Ken Shiratori, Ashraf Amanullah, Robert Kiss, Jincai Li, Martin Gawlitzek, Robert Shawley
Publikováno v:
Encyclopedia of Industrial Biotechnology
Fed-batch cell culture processes are the standard platform technology for the synthesis of high value biopharmaceutical proteins. Recent advances in cell line development and in the optimization of culture medium have enabled the operation of fed-bat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05dcb6b4e8a681cb9be4f5a4532e67b3
https://doi.org/10.1002/9780470054581.eib030
https://doi.org/10.1002/9780470054581.eib030
Autor:
Martin Gawlitzek, Sven Markert, Wendy Hsu, Ulrike Caudill, Chris Caffalette, Oliver Popp, Steve Meier, Abby Pynn, Andy A. Lin, Masaru Ken Shiratori, Robert Shawley, Thomas Tröbs
Publikováno v:
BMC Proceedings
New chemically defined platform media (basal and feed) were developed by leveraging data and knowledge from the two Genentech and Roche legacy platform processes, and through a series of experiments including high-throughput systems for cell culture,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fa98fce607f85c834973fe94cc653d
http://europepmc.org/articles/PMC3981517
http://europepmc.org/articles/PMC3981517