Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Masaru Inage"'
Autor:
J. Yuzuru Homma, Takushi Tadakuma, Tatsuji Yasuda, Toru Tsumita, Masaru Inage, Tetsuo SHlBA, Shiro Kanegasaki, Shoichi Kusumoto
Publikováno v:
European Journal of Biochemistry. 124:405-407
The adjuvant effect of synthetic analogues of lipid A was investigated in tnice in vivo. Two cbf the five synthetic lipid A analogues showed adjuvant activity when they were incorporated into dipalmitoylglyceerophosphocholine-cholesterol-dipalmitoylg
Publikováno v:
Organometallics. 10:2921-2930
Autor:
Toru Tsumita, Shiro Kanegasaki, Masaru Inage, Takushi Tadakuma, Tatsuji Yasuda, Nobunao Ikewaki, Shoichi Kusumoto, J. Yuzuru Homma, Tetsuo Shiba
Publikováno v:
European Journal of Biochemistry. 140:245-248
In the previous paper [Eur. J. Biochem. 124, 405 (1982)], we demonstrated that chemically synthesized lipid-A analogues such as the 1-monophosphate or 1,4'-diphosphate of 6-O-(2-deoxy-2-tetradecanoylamino-6-O-tetradecanoyl-D-glucopyra nos yl)-2-deoxy
Autor:
Haruyuki Chaki, Tetsuo Shiba, Shoichi Kusumoto, Tetsuo Shimamoto, Masahiro Imoto, Masaru Inage
Publikováno v:
Clinical Infectious Diseases. 6:478-482
For elucidation of a relationship between chemical structure and biologic activity of lipid A, syntheses of 13 derivatives of glucosamine beta (1-6) disaccharide, which were acylated at 3, 4, and 6'-hydroxyl groups and/or phosphorylated at positions
Autor:
Tetsuo Shiba, Tetsuo Shimamoto, Shoichi Kusumoto, Masahiro Imoto, Masaru Inage, Haruyuki Chaki
Publikováno v:
Tetrahedron Letters. 24:2011-2014
A synthetic route was established to construct the proposed structure of lipid A which consists of β (1–6) glucosamine disaccharide 1,4′-diphosphate O,N-acylated with (R)-3-hydroxy- or (R)-3-acyloxytetradecanoic acid.
Autor:
Tetsuo Shiba, Shoichi Kusumoto, Masaru Inage, Masaaki Nakahata, Haruyuki Chaki, Akira Tai, Yoshiharu Izumi, Tadao Harada
Publikováno v:
Chemistry Letters. 9:1373-1376
Synthesis is described on 6-O-[2-deoxy-2-((R)-3-hydroxytetradecanoylamino)-6-O-tetradecanoyl-β-D-glucopyranosyl]-2-deoxy-2-((R)-3-hydroxytetradecanoylamino)-3,4-di-O-tetradecanoyl-D-glucopyranose which corresponds to the phosphate-less lipid A struc
Autor:
Motohiro Matsuura, Masaru Inage, Nobuyuki Shibukawa, Yasuhiko Kojima, Yoshiyuki Kubota, Masatoshi Shibata, J. Yuzuru Homma, Tetsuo Shiba, Shoichi Kusumoto
Publikováno v:
European Journal of Biochemistry. 137:639-642
Interferon-inducing, pyrogenic and proclotting enzyme of horseshoe crab activation activities of chemically synthesized lipid A analogues were investigated and compared with the same activities of a natural lipid A. These analogues are nonphosphoryla
Publikováno v:
Tetrahedron Letters. 21:3889-3892
6- O -(2-Deoxy-2-myristoylamino-6- O -myristoyl-β-D-glucopyranosyl)-2-deoxy-2-myristoylamino-3,4-di- O -myristoyl-D-glucopyranose ( 2 ) was prepared in a synthetic approach to lipid A which is the active center of bacterial endotoxin.
Publikováno v:
Tetrahedron Letters. 22:2281-2284
1-α-Monophosphate ( 2 ), 4′-monophosphate ( 3 ), and 1-α, 4′-diphosphate ( 4 ) of 6-0-(2-deoxy-2-tetradecanoylamino-6-0-tetradecanoyl-β-D-glucopyranosyl) -2-deoxy-2-tetradecanoylamino-3, 4-di -0-tetradecanoyl-D-glucopyranose were prepared in o
Autor:
Shoichi Kusumoto, Hidemasa Ogawa, Tetsuo Shiba, N Sawaki, O Nagase, Kensuke Matsumoto, Masaru Inage, Ichiro Azuma, T Kusama
Publikováno v:
Infection and Immunity. 32:748-758
The experimental system utilized in investigating the correlation between the chemical structures of muramyl peptides and their protective activities in the sepsis type of systemic infections caused by Escherichia coli was applied in evaluating the e