Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Masaru Himeno"'
Autor:
Atsushi Umeda, Hideaki Fujita, Toshio Kuronita, Kaori Hirosako, Masaru Himeno, Yoshitaka Tanaka
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1821-1832 (2003)
It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-
Externí odkaz:
https://doaj.org/article/c43c9ec234e84cdabaace4ba32f91d6c
Autor:
Takayuki Koga, Takumi Ishida, Tomoki Takeda, Yuji Ishii, Hiroshi Uchi, Kiyomi Tsukimori, Midori Yamamoto, Masaru Himeno, Masutaka Furue, Hideyuki Yamada
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40322 (2012)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), an endocrine disruptor, causes reproductive and developmental toxic effects in pups following maternal exposure in a number of animal models. Our previous studies have demonstrated that TCDD imprints sexual
Externí odkaz:
https://doaj.org/article/3d1a8f5502344467920dcd4f069e5a12
Autor:
Yuji Ishii, Hideyuki Yamada, Takao Shimazoe, Tomoki Takeda, Misaki Fujii, Masaru Himeno, Midori Yamamoto, Yukiko Hattori
Publikováno v:
Molecular Pharmacology. 85:74-82
Our previous studies have shown that treatment of pregnant rats with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 1 μg/kg) at gestational day (GD) 15 reduces the pituitary synthesis of luteinizing hormone (LH) during the late fetal and early postnatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f66b25352e2a35554001f660ea9d05
https://doi.org/10.1124/mol.113.088575
https://doi.org/10.1124/mol.113.088575
Autor:
Tamotsu Yoshimori, Yoshitaka Tanaka, Masaru Himeno, Sadaki Yokota, Ryo Tachiyama, Daisuke Ishikawa, Hideaki Fujita, Keiichi I. Nakayama, Masaki Matsumoto
Publikováno v:
Genes to Cells. 16:448-466
Ubiquitylation of membrane proteins triggers their endocytosis at the plasma membrane and subsequent lysosomal degradation through multivesicular bodies (MVBs). A dominant-negative mutant SKD1/Vps4B caused an accumulation of ubiquitylated membrane pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a716120f8b6ad44212a97672c8924b6
https://doi.org/10.1111/j.1365-2443.2011.01499.x
https://doi.org/10.1111/j.1365-2443.2011.01499.x
Autor:
Shinji Takechi, Tadatoshi Yamaguchi, Takumi Ishida, Masaru Himeno, Tomoki Takeda, Hideyuki Yamada, Midori Yamamoto, Yuji Ishii
Publikováno v:
The Journal of Toxicological Sciences. 36:221-229
Our previous studies have demonstrated that maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes a reduction in gonadotropin biosynthesis in the fetal pituitary, resulting in the attenuated expression of steroidogenic proteins in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d9a16d5dd66f07eba3f9a5d686e41f
https://doi.org/10.2131/jts.36.221
https://doi.org/10.2131/jts.36.221
Autor:
Keiichi I. Nakayama, Takaichi Fukuda, Naoki Shigematsu, Tomoko Kadowaki, Taku Yamaguchi, Kenji Yamamoto, Masaru Himeno, Takayuki Tsukuba, Kuniaki Okamoto, Shun Higuchi, Tsuneyuki Yamamoto, Tsuyoshi Nishioku
Publikováno v:
Journal of Neurochemistry. 105:1394-1404
Cathepsin E is an endolysosomal aspartic proteinase predominantly expressed in cells of the immune system, but physiological functions of this protein in the brain remains unclear. In this study, we investigate the behavioral effect of disrupting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a943ce1c00cb1a288f3cf7f1983df657
https://doi.org/10.1111/j.1471-4159.2008.05242.x
https://doi.org/10.1111/j.1471-4159.2008.05242.x
Autor:
Jun Kawai, Yoshihide Hayashizaki, Kanako Imamura, Kazumi Ishidoh, Tamotsu Yoshimori, Yoshitaka Tanaka, Masaru Himeno, Daisuke Ishikawa, Yusuke Umezuki, Atsuki Nara, Hideaki Fujita, Seiko Uchimura
Publikováno v:
Journal of Cell Science. 117:2997-3009
SKD1 belongs to the AAA-ATPase family and is one of the mammalian class E Vps (vacuolar protein sorting) proteins. Previously we have reported that the overexpression of an ATPase activity-deficient form of SKD1 (suppressor of potassium transport gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f678f01c5d7d192d8e8f8274ff30e9
https://doi.org/10.1242/jcs.01170
https://doi.org/10.1242/jcs.01170
Publikováno v:
European Journal of Cell Biology. 83:369-380
LIM kinase (LIMK) plays a critical role in stimulus-induced remodeling of the actin cytoskeleton by linking signals from the Rho family GTPases to changes in cofilin activity. Recent studies have shown an important role for LIMK1 signaling in tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7761ce2933bad11110b10aa0a746a59
https://doi.org/10.1078/0171-9335-00382
https://doi.org/10.1078/0171-9335-00382
Autor:
Hideaki Fujita, Atsushi Umeda, Masaru Himeno, Toshio Kuronita, Kaori Hirosako, Yoshitaka Tanaka
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 10, Pp 1821-1832 (2003)
It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d714be913250185e5e301859c3ebbb66
http://www.sciencedirect.com/science/article/pii/S0022227520336993
http://www.sciencedirect.com/science/article/pii/S0022227520336993
Publikováno v:
Scopus-Elsevier
Small GTPase Rho and its downstream effectors, ROCK family of Rho-associated serine-threonine kinases, are thought to participate in cell morphology, motility, and tumor progression through regulating the rearrangement of actin cytoskeleton. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a88139d4864f7534035acbc063e507
https://doi.org/10.1007/bf03033750
https://doi.org/10.1007/bf03033750