Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Masaru Akiyama"'
Autor:
Ruriko Fujimoto, Ysuharu Ohta, Konosuke Masuda, Akihiko Taguchi, Masaru Akiyama, Kaoru Yamamoto, Hiroko Nakabayashi, Yuko Nagao, Takuro Matsumura, Syunsuke Hiroshige, Yasuko Kajimura, Makoto Akashi, Yukio Tanizawa
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 9, Pp 1496-1505 (2022)
Abstract Aims/Introduction Understanding morning–evening variation in metabolic state is critical for managing metabolic disorders. We aimed to characterize this variation from the viewpoints of insulin secretion and insulin sensitivity, including
Externí odkaz:
https://doaj.org/article/beb03a85e06c4f5486ed371cc7ca4bc2
Autor:
Risa Suetomi, Yasuharu Ohta, Masaru Akiyama, Takuro Matsumura, Akihiko Taguchi, Kaoru Yamamoto, Takashi Kamatani, Yukio Tanizawa
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 823-833 (2020)
Abstract Aims/Introduction Pancreatic β‐cells are sensitive to endoplasmic reticulum (ER) stress, which has a major role in the context of β‐cell death. Adrenomedullin (ADM) has been shown to exert a cytoprotective effect under various pathophy
Externí odkaz:
https://doaj.org/article/ff266980d0db4e78a9cd67535423995a
Autor:
Yasuharu Ohta, Akihiko Taguchi, Takuro Matsumura, Hiroko Nakabayashi, Masaru Akiyama, Kaoru Yamamoto, Ruriko Fujimoto, Risa Suetomi, Akie Yanai, Koh Shinoda, Yukio Tanizawa
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 146-156 (2017)
In Wfs1−/− Ay/a islets, in association with endoplasmic reticulum (ER) stress, D-site-binding protein (Dbp) expression decreased and Nuclear Factor IL-3 (Nfil3)/E4 Promoter-binding protein 4 (E4bp4) expression increased, leading to reduced DBP tr
Externí odkaz:
https://doaj.org/article/c36990adf12945068ddf4e83461974bf
Autor:
Kimie Matsunaga, Katsuya Tanabe, Hiroshi Inoue, Shigeru Okuya, Yasuharu Ohta, Masaru Akiyama, Akihiko Taguchi, Yukari Kora, Naoko Okayama, Yuichiro Yamada, Yasuhiko Wada, Shin Amemiya, Shigetaka Sugihara, Yuzo Nakao, Yoshitomo Oka, Yukio Tanizawa
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106906 (2014)
BACKGROUND: Wolfram syndrome (WFS) is a recessive neurologic and endocrinologic degenerative disorder, and is also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy and Deafness) syndrome. Most affected in
Externí odkaz:
https://doaj.org/article/24509e5a11404243807f239b76ed7a91
Autor:
Franco Folli, Terumasa Okada, Carla Perego, Jenny Gunton, Chong Wee Liew, Masaru Akiyama, Anna D'Amico, Stefano La Rosa, Claudia Placidi, Roberto Lupi, Piero Marchetti, Giorgio Sesti, Marc Hellerstein, Lucia Perego, Rohit N Kulkarni
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e28050 (2011)
Insulin resistance, reduced β-cell mass, and hyperglucagonemia are consistent features in type 2 diabetes mellitus (T2DM). We used pancreas and islets from humans with T2DM to examine the regulation of insulin signaling and cell-cycle control of isl
Externí odkaz:
https://doaj.org/article/23505363de844bbd8c545a0c63de5f09
Publikováno v:
Antarctic Record, Vol 35, Iss 3, Pp 285-295 (1991)
The species composition and distribution of soil algae in situ were investigated by the direct observation using the contact slide method with reference to the available water in soils of the Yukidori Valley, Langhovde, Antarctica. Glass slides were
Externí odkaz:
https://doaj.org/article/1f238ada6c1948e88ad0e665c0ce382e
Autor:
Masaru AKIYAMA
Publikováno v:
Antarctic Record, Iss 32, Pp 71-77 (1968)
A list of terrestrial and subterranean micro algae recognized on the Ongul Islands, Antarctica is given. In the list are enumerated twenty-eight genera and thirty-two species of algae including sixteen species of Chlorophyceae, four species of Xantho
Externí odkaz:
https://doaj.org/article/a3f06fb3611f4fd19e33e2eeaebbca24
Autor:
Masaru Akiyama, Satoru Kawasaki
Publikováno v:
Acta geotechnica. 14(3):685-696
Biogrouting is a ground improvement technique, which utilizes microorganisms. The numerical simulation of biogrouting is important to ensure efficient operation and to assess the applicability to the target ground. In this study, we compared syringe-
Autor:
Masaru Akiyama, Satoru Kawasaki
Publikováno v:
Japanese Geotechnical Journal. 12:337-349
Autor:
Chong Wee Liew, Rohit N. Kulkarni, Masaru Akiyama, Shusheng Lu, Robert T. Kennedy, Jiang Hu, Ben Hambro, Rachael Martinez
Publikováno v:
Diabetes
Patients with type 2 diabetes (T2D) often exhibit hyperglucagonemia despite hyperglycemia, implicating defective α-cell function. Although endoplasmic reticulum (ER) stress has been suggested to underlie β-cell dysfunction in T2D, its role in α-ce