Longitudinal changes in clozapine dose in patients with treatment-resistant schizophrenia: a 5-year retrospective cohort study

Autor: Masaru, Tsukahara, Ryuhei, So, Shinichiro, Nakajima, Kohei, Kitagawa, Masafumi, Kodama, Hiroyoshi, Takeuchi

Publikováno v: International Clinical Psychopharmacology. 38:96-101

This retrospective cohort study aimed to investigate the longitudinal changes in clozapine dose over a 5-year period in patients with treatment-resistant schizophrenia (TRS). Patients with TRS who were administered clozapine at a hospital between Apr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4dee53ba65dbd02ed0750daf3dfd24
https://doi.org/10.1097/yic.0000000000000429

Clinical Utility and Safety of Slower-than-Recommended Titration of Clozapine for Treatment-Resistant Schizophrenia: a Retrospective Cohort Study

Autor: Yoshiki Kishi, Yuji Yada, Masafumi Kodama, Masaru Tsukahara, Ryuhei So

Publikováno v: Psychiatric Quarterly. 92:703-713

Slow titration of clozapine is recommended given the risk of serious adverse effects. However, the utility and safety of slower-than-recommended titration of clozapine remain unclear. Consequently, we aimed to investigate the clinical utility and saf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f532dd9c8a1bddf6d2b4e5f6f1afd1b9
https://doi.org/10.1007/s11126-020-09841-3

An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels

Autor: Jose de Leon, Georgios Schoretsanitis, Robert L. Smith, Espen Molden, Anssi Solismaa, Niko Seppälä, Miloslav Kopeček, Patrik Švancer, Ismael Olmos, Carina Ricciardi, Celso Iglesias-Garcia, Ana Iglesias-Alonso, Edoardo Spina, Can-Jun Ruan, Chuan-Yue Wang, Gang Wang, Yi-Lang Tang, Shih-Ku Lin, Hsien-Yuan Lane, Yong Sik Kim, Se Hyun Kim, Anto P. Rajkumar, Dinora F. González-Esquivel, Helgi Jung-Cook, Trino Baptista, Christopher Rohde, Jimmi Nielsen, Hélène Verdoux, Clelia Quiles, Emilio J. Sanz, Carlos De Las Cuevas, Dan Cohen, Peter F.J. Schulte, Aygün Ertuğrul, A. Elif Anıl Yağcıoğlu, Nitin Chopra, Betsy McCollum, Charles Shelton, Robert O. Cotes, Arun R. Kaithi, John M. Kane, Saeed Farooq, Chee H. Ng, John Bilbily, Christoph Hiemke, Carlos López-Jaramillo, Ian McGrane, Fernando Lana, Chin B. Eap, Manuel Arrojo-Romero, Flavian Ş. Rădulescu, Erich Seifritz, Susanna Every-Palmer, Chad A. Bousman, Emmanuel Bebawi, Rahul Bhattacharya, Deanna L. Kelly, Yuji Otsuka, Judit Lazary, Rafael Torres, Agustin Yecora, Mariano Motuca, Sherry K.W. Chan, Monica Zolezzi, Sami Ouanes, Domenico De Berardis, Sandeep Grover, Ric M. Procyshyn, Richard A. Adebayo, Oleg O. Kirilochev, Andrey Soloviev, Konstantinos N. Fountoulakis, Alina Wilkowska, Wiesław J. Cubała, Muhammad Ayub, Alzira Silva, Raphael M. Bonelli, José M. Villagrán-Moreno, Benedicto Crespo-Facorro, Henk Temmingh, Eric Decloedt, Maria R. Pedro, Hiroyoshi Takeuchi, Masaru Tsukahara, Gerhard Gründer, Marina Sagud, Andreja Celofiga, Dragana Ignjatovic Ristic, Bruno B. Ortiz, Helio Elkis, António J. Pacheco Palha, Adrián LLerena, Emilio Fernandez-Egea, Dan Siskind, Abraham Weizman, Rim Masmoudi, Shamin Mohd Saffian, Jonathan G. Leung, Peter F. Buckley, Stephen R. Marder, Leslie Citrome, Oliver Freudenreich, Christoph U. Correll, Daniel J. Müller

Publikováno v: De Leon, J, Schoretsanitis, G, Smith, R L, Molden, E, Solismaa, A, Seppälä, N, Kopeček, M, Švancer, P, Olmos, I, Ricciardi, C, Iglesias-Garcia, C, Iglesias-Alonso, A, Spina, E, Ruan, C J, Wang, C Y, Wang, G, Tang, Y L, Lin, S K, Lane, H Y, Kim, Y S, Kim, S H, Rajkumar, A P, González-Esquivel, D F, Jung-Cook, H, Baptista, T, Rohde, C, Nielsen, J, Verdoux, H, Quiles, C, Sanz, E J, De Las Cuevas, C, Cohen, D, Schulte, P F J, Ertuǧrul, A, Anll Yaǧcloǧlu, A E, Chopra, N, McCollum, B, Shelton, C, Cotes, R O, Kaithi, A R, Kane, J M, Farooq, S, Ng, C H, Bilbily, J, Hiemke, C, López-Jaramillo, C, McGrane, I, Lana, F, Eap, C B, Arrojo-Romero, M, Rǎdulescu, F, Seifritz, E, Every-Palmer, S, Bousman, C A, Bebawi, E, Bhattacharya, R, Kelly, D L, Otsuka, Y, Lazary, J, Torres, R, Yecora, A, Motuca, M, Chan, S K W, Zolezzi, M, Ouanes, S, De Berardis, D, Grover, S, Procyshyn, R M, Adebayo, R A, Kirilochev, O O, Soloviev, A, Fountoulakis, K N, Wilkowska, A, Cubała, W J, Ayub, M, Silva, A, Bonelli, R M, Villagrán-Moreno, J M, Crespo-Facorro, B, Temmingh, H, Decloedt, E, Pedro, M R, Takeuchi, H, Tsukahara, M, Gründer, G, Sagud, M, Celofiga, A, Ignjatovic Ristic, D, Ortiz, B B, Elkis, H, Pacheco Palha, A J, Llerena, A, Fernandez-Egea, E, Siskind, D, Weizman, A, Masmoudi, R, Mohd Saffian, S, Leung, J G, Buckley, P F, Marder, S R, Citrome, L, Freudenreich, O, Correll, C U & Müller, D J 2022, ' An International Adult Guideline for Making Clozapine Titration Safer by Using Six Ancestry-Based Personalized Dosing Titrations, CRP, and Clozapine Levels ', Pharmacopsychiatry, vol. 55, no. 2, pp. 73-86 . https://doi.org/10.1055/a-1625-6388

This international guideline proposes improving clozapine package inserts worldwide by using ancestry-based dosing and titration. Adverse drug reaction (ADR) databases suggest that clozapine is the third most toxic drug in the United States (US), and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c69e293db54415a8bfeda3a4a06ea2f
http://hdl.handle.net/20.500.12278/124424

Incidence and predictors of acute akathisia in severely ill patients with first-episode schizophrenia treated with aripiprazole or risperidone: secondary analysis of an observational study

Autor: Bunta Yoshimura, Shinji Sakamoto, Yusaku Yoshimura, Ryuhei So, Kojiro Sato, Masaru Tsukahara

Publikováno v: Psychopharmacology. 236:723-730

In the antipsychotic treatment of schizophrenia with little medication history, especially in drug-naive cases, predictors of side effects are important. However, predictors of antipsychotic-induced akathisia remain unclear. This study aimed to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0191cc44c032713d3d1a132a0b508874
https://doi.org/10.1007/s00213-018-5101-7