Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Masao Sunaga"'
Autor:
Masao Sunaga, Akihiko Hirose, Hina Kato, Hideki Serizawa, Atsushi Ono, Mutsuko Hirata-Koizumi, Eiichi Kamata, Mariko Matsumoto, Mika Takahashi
Publikováno v:
The Journal of Toxicological Sciences. 37:463-474
Three female Crl:CD(SD) rats/group were dosed with single wall carbon nanotube (SWCNT) or multi wall carbon nanotube (MWCNT) four times by gavage at a total of 50 mg/kg bw or 200 mg/kg bw (four equally divided doses at one-hour intervals). Acute oral
Autor:
Hironao Horikawa, Ryuichi Hasegawa, Tomonori Enami, Eiichi Kamata, Mutsuko Koizumi, Masao Sunaga, Nobuo Nishimura
Publikováno v:
The Journal of Toxicological Sciences. 27:411-421
Repeated dose toxicity of 3-aminophenol was examined on oral administration to newborn and young rats, and susceptibility was analyzed in terms of the no observed adverse effect level (NOAEL) and the unequivocally toxic level. In the 18-day newborn r
Autor:
Isao Narama, Masao Sunaga, Yoshihiro Takei, Yuko Yamaguchi, Yoshimasa Okazaki, Takafumi Yoshioka, Kiyoshi Imai, Makiko Yamaguchi, Masao Hamamura, Kunitoshi Mitsumori, Hijiri Iwata, Yasuyoshi Okuno, Shinsuke Yoshimura, Masaaki Okada, Satsuki Hoshuyama
Publikováno v:
Journal of Toxicologic Pathology. 14:279-287
In order to standardize test procedures for evaluation of neurotoxicity of chemical exposure, a collaborative study with a common protocol based on the Organization for Economic Cooperation and Development (OECD) test guideline TG407 was conducted by
Autor:
Tatsuya Fukuda, Yukio Kodama, Kunitoshi Mitsumori, Masao Sunaga, Naochika Matsunuma, Hiroshi Suzuki, Hideaki Okamiya, Tatsuji Nomura, Sunao Manabe, Gakushi Nomura, Shigeharu Wakana, Yoshiyuki Sakamaki, Satoshi Yamamoto, Yuzo Hayashi, Kyoji Hioki
Publikováno v:
Carcinogenesis. 17:2455-2461
In this study, we investigated the carcinogenic response of transgenic mice carrying the human prototype c-Ha-ras gene, namely Tg rasH2/CB6F1 mice, to various genotoxic carcinogens and compared it with that of control non-transgenic CB6F1 mice (non-T
Autor:
Masao Sunaga, Makoto Ema, Akihiko Hirose, Mika Takahashi, Eiichi Kamata, Mutsuko Hirata-Koizumi
Publikováno v:
Environmental toxicology. 24(1)
Rats were treated by gavage once daily with 2,4-dinitrophenol (DNP) at 0 (control), 3, 10, or 30 mg/kg bw. Males were dosed for 46 days, beginning 14 days before mating, and females were dosed for 40-47 days, from 14 days before mating to day 3 of la
Autor:
Yoshihiko Ito, Ryuichi Hasegawa, Mutsuko Hirata-Koizumi, Masao Sunaga, Makoto Ema, Nobuo Nishimura, Mika Takahashi, Sakiko Fujii, Eiichi Kamata
Publikováno v:
Congenital anomalies. 46(1)
Newborn rat studies were conducted with oral administration of 3-ethylphenol (3EP) and 4-ethylphenol (4EP) on postnatal days (PND) 4-21 to allow comparison of no observed adverse effect level (NOAEL) and unequivocally toxic level (UETL) with those fr
Autor:
Shuzo, Okazaki, Hiromasa, Takashima, Makiko, Yamaguchi, Masao, Hamamura, Kotaro, Yamashita, Masaaki, Okada, Masao, Sunaga, Ryota, Tanaka, Shinichi, Sato, Takaaki, Umano, Ryozo, Tsuji, Takafumi, Yosioka, Tomoko, Fujii
Publikováno v:
The Journal of toxicological sciences. 28
In order to clarify technical problems in evaluating neurotoxicity of chemicals and to solve them, a collaborative study with a common protocol was conducted at 11 domestic safety research laboratories. In the collaborative study, acrylamide and IDPN
Autor:
Hiroaki Muto, Ayako Yoshida, Mariko Hirata, Jyun-ichi Nagaya, Hitoshi Shigeno, Masatoshi Furukawa, Masao Sunaga, Sakae Obara
Publikováno v:
The Journal of toxicological sciences. 24(1)
The toxicity of the lowest viscosity grade of hydroxypropyl methylcellulose (HPMC) that is currently commercially available was investigated by means of a three-month repeated oral administration study in male and female Crj:CD (SD) IGS rats at doses