Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Masao Seiki"'
Publikováno v:
Fisheries Science. 72:1322-1324
Autor:
Hiroko Nebiki, Mikio Ishikawa, Atsushi Nakamura, Hajime Nakamura, Masao Seiki, Hiroshi Satoh, Tetsuo Arakawa, Takashi Fukuda, Hiroyuki Sakuma, Kenzo Kobayashi
Publikováno v:
Digestive Diseases and Sciences. 35:559-566
The effects of zinc L-carnosine on ethanol-induced damage and the correlation of these effects with endogenous prostaglandin E2 were evaluated in rat gastric mucosa in vivo and in vitro. When given either intragastrically or intraperitoneally, zinc L
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:3035-3041
N-Phenoxypropylacetamide derivatives were prepared and tested for antiulcer activity. These compounds exhibited both gastric acid antisecretory and cytoprotective properties. Structure-activity studies led to the identification of N-[3-{3-(1-piperidi
Autor:
Shigeru Ueki, Eijiro Tagashira, Mitsuo Soeda, Yuko Hori, Yoshiaki Tanaka, Tomoyuki Yoneta, Hitoshi Morita, Susumu Okabe, Masao Seiki, Hiroyuki Aita
Publikováno v:
Folia Pharmacologica Japonica. 95:257-269
We investigated the anti-ulcer effects of zinc L-carnosine (Z-103) using several acute experimental models of gastric and duodenal lesions in rats. Effects of Z-103 on various gastric functions, e.g., antacid (in vitro), anti-pepsin (in vitro), gastr
Publikováno v:
The Proceedings of the Machine Design and Tribology Division meeting in JSME. :41-42
Autor:
Kazuhiro Kumagai, Etsuo Ogawa, Hiromi Ichikawa, Ichiro Yokoe, Osamu Kitagawa, Yoshiaki Shirataki, Manki Komatsu, Masanao Watanabe, Masao Seiki, Yoshiaki Muto
Publikováno v:
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 114(12)
The antiulcer activities of 59 methanol and aqueous extracts obtained from 59 crude drugs on the ethanol-HCl-induced ulceration in rats were investigated. Among them 15 extracts were selected and they were further examined for their effects on indome
Autor:
Shigeru Ueki, Eijiro Tagashira, Hitoshi Morita, Kyoji Chaki, Hiroyuki Aita, Toshihiko Takemasa, Yuko Hori, Masao Seiki, Tomoyuki Yoneta
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 100(2)
We investigated the effects of Z-103, ZnSO4, L-carnosine and solcoseryl on wound healing by dermal incision in guinea pigs. The tensile strength, hydroxyproline contents and the value of angiogenesis (carmine contents) at the wounded site of dorsal s
Autor:
Susumu Okabe, Keiko Takagi, Hideki Igata, Shinichi Kato, Kenichi Shimosako, Yoshiaki Yamaji, Masao Seiki
Publikováno v:
Japanese journal of pharmacology. 59(3)
We examined the effects of a new compound, N-[3-[3-(piperidinomethyl)phenoxy]-propyl]-2-(2-hydroxyethyl-1- thio)acetamido.2-(4-hydroxy benzoyl)benzoate (Z-300), on the histamine H2-receptor, gastric secretion in rats and dogs, and acute gastro-duoden
Autor:
Koichi Seto, Kyoji Chaki, Eijiro Tagashira, Yuko Hori, Tomoyuki Yoneta, Hitoshi Morita, Hiroko Yamada, Toshihiko Takemasa, Masao Seiki, Hiroyuki Aita
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 99(5)
We studied the healing promoting action of Z-103 on the chronic gastric ulcer induced by acetic acid (AAU) or Fe-ascorbic acid (FAU) in rats. The area of the gastric ulcers, hydroxyproline (Hyp) and DNA contents in the ulcer region were measured as a
Autor:
Seiji Toyama, Shigeru Furuta, Yuko Hori, Hitoshi Morita, Masao Seiki, Yukinori Mera, Eijiro Tagashira, Tomoyuki Yoneta, Kaneyasu Arai, Hiroyuki Aita
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 99(4)
The gastric mucosal adhesiveness of Z-103 in rats with acetic acid ulcer was studied macroscopically, histologically, and biochemically. From macroscopical observations, when Z-103 was orally administered to an acetic acid ulcer model, there was adhe