Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Masao Koida"'
Autor:
Ryo Fukuyama, Akio Shimokawa, Yasushi Kodama, Mitsugu Fujita, Yoshitaka Ohishi, Yuko Ando, Masao Koida, Hiromichi Nakamuta
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 2, Pp 214-220 (2011)
Abstract.: The benzo[b]furan derivative MU314 inhibits in vitro bone resorption as potently as β-estradiol (E2). Here, we examined the point of action on the anti-osteoporotic effects of MU314. MU314 (10 nM) suppressed lacunae formation by osteoclas
Externí odkaz:
https://doaj.org/article/9a65eb77bf734b59b6c8d17972d2ac6d
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(3):379-386
Autor:
Masao Koida, Ikuo Kawasaki, Yuko Ando, Takahiro Ohishi, Hidemi Kanemura, Yoshitaka Ohishi, Ryo Fukuyama, Hiromichi Nakamuta, Kiyoharu Nishide, Yukako Tabuchi, Shunsaku Ohta
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract Preparation of novel (Z)-4-ylidenebenzo[b]furo[3,2-d][1,3]oxazines and their biological activities such as anti-osteoclastic bone resorption activity, antagonistic activity of the cysLT1 receptor and growth inhibitory activity for
Autor:
Kumiko Ando, Shunsaku Ohta, Masao Koida, Yoshitaka Ohishi, Jun-ichi Kunitomo, Mami Yamaguchi, Masayuki Yamashita, Yuko Ando, Hiromichi Nakamuta, Ryo Fukuyama
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:5849-5854
A novel oxazine ring formation method was established using the reaction of 2-acetyl-( E )-3-styrylcarbonylaminobenzo[ b ]furans ( 4 ) with Vilsmeier–Haack–Arnold reagent to afford ( E and Z )-(( E )-2-styrylbenzo[ b ]furo[3,2- d ][1,3]oxazin-4-y
Autor:
Masao Koida, Ryo Fukuyama, Hiromichi Nakamuta, Ippei Tanaka, Nobuo Izumo, Satoshi Shimegi, Atsushi Kiuchi
Publikováno v:
International Journal of Sport and Health Science. 4:10-18
The purpose of this study was to investigate the effects of different intensities of resistance exercise training on established bone loss in ovariectomized (ovx-ed) rats by densitometry and histomorphometry. Thirty Female Wistar rats were ovx-ed or
Autor:
Toshihisa Komori, Takashi Fujita, Masao Koida, Hiromichi Nakamuta, Yasu-Taka Azuma, Akihiko Hirano, Ryo Fukuyama
Publikováno v:
Biochemical and Biophysical Research Communications. 315:636-642
Cell migration is a key event in repair and remodeling of skeletal tissues, but the mechanism of osteoblast migration has not been resolved. Statins, which are inhibitors of 3-hydroxy-3-methylglutaryl CoA reductase, increase bone. However, the effect
Publikováno v:
Journal of Biological Chemistry. 277:22191-22200
cAMP signaling, activated by extracellular stimuli such as parathyroid hormone, has cell type-specific effects important for cellular proliferation and differentiation in bone cells. Recent evidence of a second enzyme target for cAMP suggests diverge
Autor:
Takeyuki Kohno, Takashi Fujita, Masao Koida, Tohru Meguro, Hiromichi Nakamuta, Ryo Fukuyama, Nobuo Izumo
Publikováno v:
Biochemical and Biophysical Research Communications. 280:348-352
Inorganic phosphate (Pi) supplement is generally used to accelerate mineralization of cultured bone cells but the mechanism of action is totally unknown. How the action is related with the transactivation of Runx2/Cbfa1,a master gene product of bone
Autor:
Masao Koida, Ryo Fukuyama, Nobuo Izumo, Hiromichi Nakamuta, Takao Hirai, Toru Meguro, Takashi Fujita
Publikováno v:
Japanese Journal of Pharmacology. 86:405-416
During 28-day culture of bone marrow- and calvaria-derived osteoblasts, the constant presence of parathyroid hormone (PTH)(1 − 34) retarded differentiation and nodule formation (NF) in a dose-dependent fashion (C-phase). In contrast, addition of PT
Autor:
Hiromichi Nakamuta, Takeyuki Kohno, Masakatsu Nomura, Tadashi Inoue, Masao Yanaka, Yohko Sugie, Toshiyo Ogouchi, Hiroki Sakurai, Masao Koida, Akira Yanagawa, Kazuhito Watabe, Noriaki Murasugi
Publikováno v:
Journal of Clinical Laboratory Analysis. 12:356-362
A sandwich transfer enzyme immunoassay for elcatonin (ECT) and its usability for the pharmacokinetic study are described. The anti‐salmon calcitonin (SCT) antibody was used for the present assay. The assay procedure consisted of the reaction of ECT