Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Masao Izawa"'
Autor:
Masao Izawa, Fuminori Taniguchi
Publikováno v:
Journal of the Endocrine Society. 6:A657-A658
Background Endometriosis has been accepted as an estrogen-dependent disease for more than two decades. So far, estrogen modulators that targeting estrogen depletion in endometriotic lesions have been expected as the first option of treatments to impr
Publikováno v:
Journal of the Endocrine Society
BACKGROUND: Endometriosis is an estrogen-dependent, inflammatory disease, and the role of estrogen is obvious because the symptoms associated with endometriosis often disappear after menopause, and GnRH agonists or progestin relieve the pelvic lesion
Publikováno v:
Journal of the Endocrine Society
[Background]Endometriosis is an estrogen-dependent, inflammatory disease characterized by the presence of endometrium-like tissue primarily on the pelvic peritoneum and ovaries. There is accumulating evidence suggesting epigenetic aberrations play a
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 81(2)
Problem Genome-wide profiling of DNA methylation in endometriotic cells has shown a distinct facet of epigenetic backgrounds; however, specific DNA methylation sites responsible for aberrant gene expression in endometriosis were unknown. Are there sp
Autor:
Fuminori Taniguchi, Hiroko Higaki, Kohkichi Hata, Tasuku Harada, Masao Izawa, Imari Deura, Yukihiro Azuma, Tomio Iwabe, Eriko Hirakawa
Publikováno v:
American Journal of Reproductive Immunology. 71:278-285
Problem How is the tumor necrosis factor (TNF) α-induced inhibitor of apoptosis (IAP) protein expression in endometriotic stromal cells (ESCs) involved in cell viability and signaling pathways? Method of study Endometriotic stromal cells were isolat
Publikováno v:
Frontiers in Bioscience. :900-910
Endometriosis is an estrogen-dependent inflammatory disease. In endometriotic tissues, a high-estrogen environment associated with up-regulation of the aromatase gene has been well documented. There is accumulating evidence supporting a concept that
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 23(7)
The molecular background of estrogen receptor (ER) expression is important to understand the pathophysiology of the high estrogen environment in endometriosis. However, the molecular details have not been fully understood. The objective of this study
Autor:
Tasuku Harada, Takashi Uegaki, Eri Takai, Tomio Iwabe, Masao Izawa, Fuminori Taniguchi, Naoki Terakawa
Publikováno v:
Fertility and Sterility. 95:33-39
Objective To search for the demethylated cytosine-phosphate-guanine (CpG) islands within the aromatase gene in stromal cells derived from endometriotic chocolate cysts. Design Prospective study. Setting Department of Obstetrics and Gynecology and Dep
Autor:
Tasuku Harada, Ayako Watanabe, Masao Izawa, Takashi Uegaki, Kana Suou, Fuminori Taniguchi, Eri Takai, Naoki Terakawa
Publikováno v:
Human Reproduction. 24:3172-3179
BACKGROUND Decreased susceptibility of endometrial tissue to apoptosis may contribute to the pathogenesis of endometriosis. We investigate the role of survivin in the pathophysiology of endometriosis through the ability of ectopic and eutopic endomet
Publikováno v:
Fertility and Sterility. 89:1390-1396
Objective To examine the molecular basis of aromatase expression in stromal cell culture from endometriotic chocolate cysts. Design Prospective study. Setting Department of Obstetrics and Gynecology and Department of Biosignaling, Tottori University,