Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Masao Goda"'
Autor:
Kazuhito Ikeda, Masao Goda, Shiori Taga, Kantaro Nishigori, Takeshi Enomoto, Yuki Fujii, Ayaka Tatara, Atsushi Kitamura, Mami Kamada, Takashi Hashimoto, Yohei Nishizato
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 371:692-702
In our drug discovery program, we identified a novel orally available and brain-penetrant phosphodiesterase (PDE) 1 inhibitor, 3-methyl-7-(tetrahydro-2H-pyran-4-yl)-2-{[trans-4-(trifluoromethyl)cyclohexyl]-methoxy}imidazo[5,1-f][1,2,4]triazin-4(3H)-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25128c74d0bcc6595cd32cfaea38951d
https://doi.org/10.1124/jpet.119.260869
https://doi.org/10.1124/jpet.119.260869
Autor:
Masao Goda, Kazuhito Ikeda, Atsushi Kitamura, Erika Wada, Takeshi Enomoto, Tomokazu Nakako, Yuki Fujii
Publikováno v:
Pharmacology Biochemistry and Behavior. 205:173183
The enzyme phosphodiesterase 1 (PDE1) is highly expressed in the striatum and cortex. However, its role in corticostriatal function has not been fully investigated. The present study was aimed at evaluating the therapeutic potential of PDE1 inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04428d04bdd0f0186569a45d3bdf0eda
https://doi.org/10.1016/j.pbb.2021.173183
https://doi.org/10.1016/j.pbb.2021.173183
Autor:
Kazuhito Ikeda, Takeshi Enomoto, Masao Goda, Yohei Nishizato, Mami Kamada, Yuki Fujii, Ayaka Tatara, Atsushi Kitamura, Shiori Taga, Takashi Hashimoto, Kantaro Nishigori
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86156e4f0a8613be360413ed6fd03890
https://doi.org/10.1254/jpssuppl.93.0_2-p-163
https://doi.org/10.1254/jpssuppl.93.0_2-p-163
Publikováno v:
Moleculargeneral genetics : MGG. 249(3)
The biosynthetic pathway for production of the antibiotic fosfomycin by Streptomyces wedmorensis consists of four steps including the formation of a C-P bond and an epoxide. Fosfomycin production genes were cloned from genomic DNA using S. wedmorensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adaf2202be149661f37a01e123449526
https://pubmed.ncbi.nlm.nih.gov/7500951
https://pubmed.ncbi.nlm.nih.gov/7500951