Zobrazeno 1 - 10
of 597
pro vyhledávání: '"Masao Doi"'
Autor:
Kotaro Tomuro, Mari Mito, Hirotaka Toh, Naohiro Kawamoto, Takahito Miyake, Siu Yu A. Chow, Masao Doi, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Ribosome profiling, which is based on deep sequencing of ribosome footprints, has served as a powerful tool for elucidating the regulatory mechanism of protein synthesis. However, the current method has substantial issues: contamination by r
Externí odkaz:
https://doaj.org/article/3e4840e33a634862b8c9b00c7dcca52c
Publikováno v:
AIP Advances, Vol 13, Iss 10, Pp 105315-105315-10 (2023)
One permanent characteristic of the thermodynamics of small systems is environment-dependence, also known as ensemble-dependence. Fluid molecules in soft (deformable) nano-confinement offer a special ensemble that acts as a bridge between classical i
Externí odkaz:
https://doaj.org/article/b13c70b033804f7daf205b842329da23
Autor:
Yoshiaki Yamaguchi, Iori Murai, Kaoru Goto, Shotaro Doi, Huihua Zhou, Genzui Setsu, Hiroyuki Shimatani, Hitoshi Okamura, Takahito Miyake, Masao Doi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gpr19 encodes an evolutionarily conserved orphan G-protein-coupled receptor (GPCR) with currently no established physiological role in vivo. We characterized Gpr19 expression in the suprachiasmatic nucleus (SCN), the locus of the master circ
Externí odkaz:
https://doaj.org/article/fa41915671cb49aa8c6c451ead7970fe
Autor:
Aki Yamamoto, Yuki Takahashi, Shinsuke Inuki, Shumpei Nakagawa, Kodai Nakao, Hiroaki Ohno, Masao Doi, Yoshinobu Takakura
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 9, Pp n/a-n/a (2022)
Abstract Small extracellular vesicles (sEVs) are nano‐sized vesicles secreted from various cells that contain bioactive metabolites and function as key regulators for intercellular communication. sEVs modulate diverse biological and pathological pr
Externí odkaz:
https://doaj.org/article/bc24cc8305aa43a4abd5f2dea8361a15
Autor:
Heng Lin, Yen-Sung Huang, Jean-Michel Fustin, Masao Doi, Huatao Chen, Hui-Huang Lai, Shu-Hui Lin, Yen-Lurk Lee, Pei-Chih King, Hsien-San Hou, Hao-Wen Chen, Pei-Yun Young, Hsu-Wen Chao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Polyploidy is a common feature in normal hepatocytes, however, the pathophysiological function of hepatic hyperpolyploidy is unclear. Here, the authors show that genotoxic stress induces accumulation of hyperpolyploid hepatocytes around the centrilob
Externí odkaz:
https://doaj.org/article/2a6b0a8610cd4b32b27ac9dde0bc48ce
Autor:
Masao Doi, Hiroyuki Shimatani, Yuta Atobe, Iori Murai, Hida Hayashi, Yukari Takahashi, Jean-Michel Fustin, Yoshiaki Yamaguchi, Hiroshi Kiyonari, Nobuya Koike, Kazuhiro Yagita, Choogon Lee, Manabu Abe, Kenji Sakimura, Hitoshi Okamura
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
The circadian transcription factors BMAL1:CLOCK bind to E/E′-boxes in gene regulatory elements of their targets and facilitate rhythmic expression. Here, the authors mutate the Per2 promoter E’′-box in mice and observe that cell- and tissue-aut
Externí odkaz:
https://doaj.org/article/9f27d452176741a7b1daf82753a71800
Autor:
Jiajia Zhou, Masao Doi
Publikováno v:
Entropy, Vol 24, Iss 5, p 716 (2022)
Using the Onsager variational principle, we study the dynamic coupling between the stress and the composition in a polymer solution. In the original derivation of the two-fluid model of Doi and Onuki the polymer stress was introduced a priori; theref
Externí odkaz:
https://doaj.org/article/91b7c395057a4858b0b0b3e795886d66
Autor:
Hiroyuki Shimatani, Yuichi Inoue, Yota Maekawa, Takahito Miyake, Yoshiaki Yamaguchi, Masao Doi
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252447 (2021)
Circadian clocks orchestrate multiple different physiological rhythms in a well-synchronized manner. However, how these separate rhythms are interconnected is not exactly understood. Here, we developed a method that allows for the real-time simultane
Externí odkaz:
https://doaj.org/article/df6cf564421d423cb243aebf234391a0
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Composite polymer gels with embedded nanosheets deform discontinuously without volume expansion during temperature changes, but the reason behind it is unknown. Here the authors predict theoretically that the deformation results from restrictions whi
Externí odkaz:
https://doaj.org/article/4a65241979524bfa9c34a77919affa05
Autor:
Hsu-Wen Chao, Masao Doi, Jean-Michel Fustin, Huatao Chen, Kimihiko Murase, Yuki Maeda, Hida Hayashi, Rina Tanaka, Maho Sugawa, Naoki Mizukuchi, Yoshiaki Yamaguchi, Jun-ichirou Yasunaga, Masao Matsuoka, Mashito Sakai, Michihiro Matsumoto, Shinshichi Hamada, Hitoshi Okamura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Circadian clock regulates hepatic gene expression and functions. Here Chao et al. show that alteration of circadian clock genes by Period deletion induces polyploidy in hepatocytes due to impaired regulation of Erk signaling by mitogen-activated prot
Externí odkaz:
https://doaj.org/article/00c4c91b8a014bdc961074b75b4bbb0b