Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Masanori Takehashi"'
Autor:
Hiroko Morimoto, Mito Kanatsu-Shinohara, Seiji Takashima, Shinichiro Chuma, Norio Nakatsuji, Masanori Takehashi, Takashi Shinohara
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7909 (2009)
BACKGROUND:Spermatogonial stem cells (SSCs) continuously undergo self-renewal division to support spermatogenesis. SSCs are thought to have a fixed phenotype, and development of a germ cell transplantation technique facilitated their characterization
Externí odkaz:
https://doaj.org/article/ccd5b97fa6e34a6e99bd3802ff0724c9
Autor:
Shiroh Futaki, Ikuhiko Nakase, Hisaaki Hirose, Seigo Tanaka, Akiko Okuda, Masanori Takehashi, Toshihide Takeuchi, Atsushi Ono, Shinya Tahara
Publikováno v:
Biomacromolecules. 20:1849-1859
To facilitate the cytosolic delivery of larger molecules such as proteins, we developed a new cell-penetrating peptide sequence, named Pas2r12, consisting of a repeated Pas sequence (FFLIG-FFLIG) and d-dodeca-arginine (r12). This peptide significantl
Autor:
Masanori Takehashi, Marek Banasik, Hiroe Tsukagoshi-Nagai, Todd Stedeford, Kunihiro Ueda, Toshio Kawamata, Noriaki Kinoshita, Seigo Tanaka
Septin 3 is a novel member of the septin subfamily of GTPase domain proteins. Human septin 3 was originally cloned during a screening of genes expressed in human teratocarcinoma cells induced to differentiate with retinoic acid. Alternative splicing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49d8de00e9cedd9fe3f1730f30545d4
https://europepmc.org/articles/PMC5991146/
https://europepmc.org/articles/PMC5991146/
Autor:
Shujiro Okuda, Suguru Kurokawa, Masanori Takehashi, Kunihiro Ueda, Tomoka Takatani-Nakase, Aika Maeda, Hyuma Nogusa, Yukari Kubo, Katsuya Fukuda, Seigo Tanaka, Akiko Okuda
Publikováno v:
BMC Neuroscience
Background Poly(ADP-ribose) polymerase 1 (PARP-1), which catalyzes poly(ADP-ribosyl)ation of proteins by using NAD+ as a substrate, plays a key role in several nuclear events, including DNA repair, replication, and transcription. Recently, PARP-1 was
Autor:
Kimiko Inoue, Takashi Nagasawa, Mito Kanatsu-Shinohara, Narumi Ogonuki, Takashi Shinohara, Hiroko Morimoto, Atsuo Ogura, Seiji Takashima, Masanori Takehashi
Publikováno v:
Cell Stem Cell. 11(4):567-578
SummarySpermatogonial stem cells (SSCs) reside in specific niches within seminiferous tubules. These niches are thought to secrete chemotactic factors for SSCs, because SSCs migrate to them upon transplantation. However, the identity of these chemota
Autor:
Masumi Hirabayashi, Mito Kanatsu-Shinohara, Megumi Kato-Itoh, Makoto Sanbo, Takashi Tanaka, Hiroko Morimoto, Masanori Takehashi, Takashi Shinohara, Masahito Ikawa, Yuka Morioka
Publikováno v:
Biology of Reproduction. 85:208-217
Spermatogonial stem cells (SSCs) are the only stem cells in the body with germline potential, which makes them an attractive target for germline modification. We previously showed the feasibility of homologous recombination in mouse SSCs and produced
Autor:
Robert P. Strosznajder, Kunihiro Ueda, Masanori Takehashi, Marek Banasik, Seigo Tanaka, Todd Stedeford
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Carbon tetrachloride (CCl(4)) is routinely used as a model compound for eliciting centrilobular hepatotoxicity. It can be bioactivated to the trichloromethyl radical, which causes extensive lipid peroxidation and ultimately cell death by necrosis. Ov
Autor:
Kristina E. Hill, Hiromitsu Tanaka, Masanori Takehashi, Raymond F. Burk, Nobuyoshi Esaki, Hisaaki Mihara, Seigo Tanaka, Tatsuo Kurihara, Suguru Kurokawa
Publikováno v:
Journal of Nutritional Science and Vitaminology. 57:298-305
Selenocysteine lyase (SCL) catalyzes the decomposition of L-selenocysteine to yield L-alanine and selenium by acting exclusively on l-selenocysteine. The X-ray structural analysis of rat SCL has demonstrated how SCL discriminates L-selenocysteine fro
Publikováno v:
Development, Growth & Differentiation. 52:303-310
Spermatogonial stem cells (SSCs) provide the foundation for spermatogenesis, and are unique tissue-specific stem cells because of their ability to transmit genetic information to offspring. Generation of knockout mice using mouse SSCs became feasible
Autor:
Shinichiro Chuma, Hiroyuki Miyoshi, Hiroyuki Sasaki, Takashi Shinohara, Masanori Takehashi, Isao Suetake, Norio Nakatsuji, Jiyoung Lee, Shoji Tajima, Seiji Takashima, Masaki Okano, Kenichiro Hata, Shinya Toyokuni, Mito Kanatsu-Shinohara, Y. Tanaka
Publikováno v:
Biology of Reproduction. 81:155-164
Although spermatogonial stem cells (SSCs) are committed to spermatogenesis, they may also convert to an embryonic stem cell-like pluripotent state at a low frequency. Because changes in DNA methylation patterns are associated with this conversion, we