Výsledky vyhledávání - "Masanori Mitsuishi"

Akademický článek

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men

Autor: Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

Publikováno v: Endocrine Journal, Vol 71, Iss 2, Pp 153-169 (2024)

Obesity and aging are major risk factors for several life-threatening diseases. Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, decline

Externí odkaz: https://doaj.org/article/92235c5b076e4e6488506b52c2421753

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Akademický článek

Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

Autor: Chikako Fujii, Kazutoshi Miyashita, Masanori Mitsuishi, Masaaki Sato, Kentaro Fujii, Hiroyuki Inoue, Aika Hagiwara, Sho Endo, Asuka Uto, Masaki Ryuzaki, Motowo Nakajima, Tohru Tanaka, Masanori Tamaki, Ayako Muraki, Toshihide Kawai, Hiroshi Itoh

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Abstract Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases. We focused 5-aminolevulinic acid (ALA) which act as electron carriers in the mitochondrial ele

Externí odkaz: https://doaj.org/article/3bbd0cbf26ea4990bafd6f92fe58cde9

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Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

Autor: Yo-ichi Nabeshima, Masato Yasui, Hiroshi Itoh, Kazuo Tsubota, Takashi Ono, Junichiro Irie, Masanori Mitsuishi, Hideaki Nakaya, Shin-ichiro Imai, Kazuya Yamashita, Hideyuki Okano, Shintaro Yamaguchi, Emi Inagaki, Hideo Yukioka, Shuhei Shigaki, Masataka Fujita

Publikováno v: Endocrine Journal. 67:153-160

Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels causes aging-related disorders and therapeutic approaches increasing cellular NAD+ prevent these disorders in animal models. The administration of n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7355800fce21e9e2383961788edfea4b
https://doi.org/10.1507/endocrj.ej19-0313

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Transient Dexamethasone Loading Induces Prolonged Hyperglycemia in Male Mice With Histone Acetylation in Dpp-4 Promoter

Autor: Masaki Ryuzaki, Kenichiro Kinouchi, Masanori Mitsuishi, Sho Endo, Kazutoshi Miyashita, Asuka Uto, Shu Meguro, Hiroshi Itoh, Masaaki Sato

Publikováno v: Endocrinology. 162

Glucocorticoid causes hyperglycemia, which is common in patients with or without diabetes. Prolonged hyperglycemia can be experienced even after the discontinuation of glucocorticoid use. In the present study, we examined the time course of blood glu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326fe7ead59182f10841698e5f3c24f1
https://doi.org/10.1210/endocr/bqab193

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Ghrelin treatment improves physical decline in sarcopenia model mice through muscular enhancement and mitochondrial activation

Autor: Masaaki Sato, Kentaro Fujii, Hiroyuki Inoue, Masanori Mitsuishi, Masanori Tamaki, Shu Wakino, Toshio Doi, Asuka Uto, Kazutoshi Miyashita, Hiroshi Itoh, Sho Endo, Chikako Fujii, Aika Hagiwara

Publikováno v: Endocrine journal. 64

Chronic kidney disease (CKD) impairs physical performance in humans, which leads to a risk of all-cause mortality. In our previous study, we demonstrated that a reduction in muscle mitochondria rather than muscle mass was a major cause of physical de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe82d96d067b6b1123b6f98c64f2160
https://pubmed.ncbi.nlm.nih.gov/28652544

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Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

Autor: Masanori Mitsuishi, Masanori Tamaki, Hiroshi Itoh, Masaki Ryuzaki, Chikako Fujii, Kazutoshi Miyashita, Hiroyuki Inoue, Tohru Tanaka, Kentaro Fujii, Toshihide Kawai, Ayako Muraki, Masaaki Sato, Motowo Nakajima, Asuka Uto, Aika Hagiwara, Sho Endo

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)

Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases. We focused 5-aminolevulinic acid (ALA) which act as electron carriers in the mitochondrial electron tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65560978003fa653cd5a38244aa3a59
https://pubmed.ncbi.nlm.nih.gov/28638045

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Chronic kidney disease reduces muscle mitochondria and exercise endurance and its exacerbation by dietary protein through inactivation of pyruvate dehydrogenase

Autor: Masanori Tamaki, Hiroshi Itoh, Shu Wakino, Kazutoshi Miyashita, Masanori Mitsuishi, Koichi Hayashi

Publikováno v: Kidney International. 85:1330-1339

Chronic kidney disease impairs physical performance. Here the time course and mechanism of muscle insufficiency in renal failure and the influence of dietary protein were studied using 5/6 nephrectomized C57Bl/6 mice, focusing on muscle mass and mito

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2a73b678f1638d03a4b4e96bf7fedd
https://doi.org/10.1038/ki.2013.473

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