Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Masanori Minoguchi"'
Autor:
Koji Teshima, Shigenobu Shibata, Atsuyuki Ashimori, Masanori Minoguchi, Charles N. Allen, Junichi Eguchi, Sayuri Tounai
Publikováno v:
British Journal of Pharmacology. 146:33-40
We synthesized a small-molecule opioid receptor-like 1 (ORL1) receptor agonist, 2-{3-[1-((1R)-acenaphthen-1-yl)piperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl}-N-methylacetamide (W-212393), and investigated its effect on the circadian body temper
Autor:
Tetsuro Fujita, Masatoshi Kiuchi, Yoshiyuki Aoki, Koji Teshima, Yukio Hoshino, Tadashi Mishina, Kunitomo Yoshitomi Phar Adachi, Masanori Minoguchi, Tokushi Hanano, Masafumi Arita, Toshiyuki Yoshitomi Pharmaceutical Ind.Ltd. Kohara, Makio Ohtsuki, Noriyoshi Nakao, Kenji Chiba, Shigeo Sasaki
Publikováno v:
Journal of Medicinal Chemistry. 43:2946-2961
A series of 2-substituted 2-aminopropane-1,3-diols was synthesized and evaluated for their lymphocyte-decreasing effect and immunosuppressive effect on rat skin allograft. A phenyl ring was introduced into the alkyl chain of the lead compound 3, whic
Autor:
Tohru Uchida, Atsuko Murata, Makoto Fujita, Katsuyuki Ogura, Makoto Noguchi, Masanori Minoguchi, Koreharu Ogata
Publikováno v:
Tetrahedron Letters. 31:3331-3334
Solid ( R )-phenylglycyl-( R )-phenylglycine (( R , R )-1) included ( S )-isopropyl phenyl sulfoxide (( S )-2) from its racemic mixture with a high enantiomeric excess. The intermolecular interactions involved in this inclusion are discussed.
Autor:
Koji, Teshima, Masanori, Minoguchi, Sayuri, Tounai, Atsuyuki, Ashimori, Junichi, Eguchi, Charles N, Allen, Shigenobu, Shibata
Publikováno v:
British journal of pharmacology. 146(1)
We synthesized a small-molecule opioid receptor-like 1 (ORL1) receptor agonist, 2-{3-[1-((1R)-acenaphthen-1-yl)piperidin-4-yl]-2,3-dihydro-2-oxo-benzimidazol-1-yl}-N-methylacetamide (W-212393), and investigated its effect on the circadian body temper
Autor:
Katsuyuki Ogura, Kazuo Ohtsuki, Masanori Minoguchi, Nobuhiro Yahata, Kazumasa Takahashi, Hirotada Iida
Publikováno v:
The Journal of Organic Chemistry. 51:508-512
Cette reaction permet l'introduction de groupes formyl et methylthiocarbonyl en α de composes carbonyles α,β-insatures