A variant of Runx2 that differs from the bone isoform in its splicing is expressed in spermatogenic cells

Autor: Satoru Kanto, Marcin Grynberg, Yoshiyuki Kaneko, Jun Fujita, Masanobu Satake

Publikováno v: PeerJ, Vol 4, p e1862 (2016)

Background. Members of the Runx gene family encode transcription factors that bind to DNA in a sequence-specific manner. Among the three Runx proteins, Runx2 comprises 607 amino acid (aa) residues, is expressed in bone, and plays crucial roles in ost

Externí odkaz: https://doaj.org/article/9a330b49c3654f2ea6a196277fa0b0e7

Supplemental Figure S1 from STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

Autor: Jennifer R. Grandis, Daniel E. Johnson, Zhenghe Wang, Masanobu Satake, William E. Gooding, Malabika Sen, Hua Li, Maria Freilino, Marie Acquafondata, Yan Zeng, Lin Wang, Noah D. Peyser

Parallel slopes indicate identical response to Stattic in PTPRT WT and KO mice. Vertical distance indicates improved outcome of Stattic-treated mice compared to vehicle-treated.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e418093feaccb99d48263312750855f
https://doi.org/10.1158/1940-6207.22533259

Data from STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

Autor: Jennifer R. Grandis, Daniel E. Johnson, Zhenghe Wang, Masanobu Satake, William E. Gooding, Malabika Sen, Hua Li, Maria Freilino, Marie Acquafondata, Yan Zeng, Lin Wang, Noah D. Peyser

Head and neck squamous cell carcinoma (HNSCC) is a frequently fatal disease due, in large part, to a high rate of second primary tumor (SPT) formation. The 4-nitroquinoline 1-oxide (4-NQO) mouse model of oral carcinogenesis provides a robust system i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce85d94aa9a445e033d63904cf521f1
https://doi.org/10.1158/1940-6207.c.6547000.v1

Twist2 promotes CD8+ T-cell differentiation by repressing ThPOK expression

Autor: Changjin Lee, Ho Lee, Sunsook Hwang, Sung Ho Jeon, Sangwook Oh, Rho Hyun Seong, Masanobu Satake, Ichiro Taniuchi, Kyung Soo Park, Jaehak Oh, Byeonggeun Kang, Yehyun Kim, Shin Jeon

Publikováno v: Cell Death & Differentiation. 27:3053-3064

CD4/CD8 T-cell lineage differentiation is a key process in immune system development; however, a defined regulator(s) that converts the signal from T-cell receptor and co-receptor complexes into lineage differentiation remains unclear. Here, we show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::938ae02afe86eb609c41dd9ed28581de
https://doi.org/10.1038/s41418-020-0560-x

STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma

Autor: Maria L. Freilino, William E. Gooding, Hua Li, Lin Wang, Zhenghe Wang, Marie Acquafondata, Masanobu Satake, Jennifer R. Grandis, Yan Zeng, Noah D. Peyser, Daniel Johnson, Malabika Sen

Publikováno v: Cancer prevention research (Philadelphia, Pa.), vol 9, iss 8
Peyser, ND; Wang, L; Zeng, Y; Acquafondata, M; Freilino, M; Li, H; et al.(2016). STAT3 as a Chemoprevention Target in Carcinogen-Induced Head and Neck Squamous Cell Carcinoma. CANCER PREVENTION RESEARCH, 9(8), 657-663. doi: 10.1158/1940-6207.CAPR-16-0089. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/09v439dg

Head and neck squamous cell carcinoma (HNSCC) is a frequently fatal disease due, in large part, to a high rate of second primary tumor (SPT) formation. The 4-nitroquinoline 1-oxide (4-NQO) mouse model of oral carcinogenesis provides a robust system i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73127d55df21969d8ed74040998be93
https://doi.org/10.1158/1940-6207.capr-16-0089