Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Masanobu Ozaki"'
Autor:
Kiyoshi Kuramoto, Yasuhiro Kawakatsu, Masaki Fujimoto, Akito Araya, Maria Antonietta Barucci, Hidenori Genda, Naru Hirata, Hitoshi Ikeda, Takeshi Imamura, Jörn Helbert, Shingo Kameda, Masanori Kobayashi, Hiroki Kusano, David J. Lawrence, Koji Matsumoto, Patrick Michel, Hideaki Miyamoto, Tomokatsu Morota, Hiromu Nakagawa, Tomoki Nakamura, Kazunori Ogawa, Hisashi Otake, Masanobu Ozaki, Sara Russell, Sho Sasaki, Hirotaka Sawada, Hiroki Senshu, Shogo Tachibana, Naoki Terada, Stephan Ulamec, Tomohiro Usui, Koji Wada, Sei-ichiro Watanabe, Shoichiro Yokota
Publikováno v:
Earth, Planets and Space, Vol 74, Iss 1, Pp 1-31 (2022)
Abstract Martian moons exploration, MMX, is the new sample return mission planned by the Japan Aerospace Exploration Agency (JAXA) targeting the two Martian moons with the scheduled launch in 2024 and return to the Earth in 2029. The major scientific
Externí odkaz:
https://doaj.org/article/8ba05a4da9864f5d8cb4470b194dca80
Autor:
Shingo Kameda, Masanobu Ozaki, Keigo Enya, Ryota Fuse, Toru Kouyama, Naoya Sakatani, Hidehiko Suzuki, Naoya Osada, Hiroki Kato, Hideaki Miyamoto, Atsushi Yamazaki, Tomoki Nakamura, Takaya Okamoto, Takahiro Ishimaru, Peng Hong, Ko Ishibashi, Takeshi Takashima, Ryoya Ishigami, Cheng-Ling Kuo, Shinsuke Abe, Yuya Goda, Hajime Murao, Saori Fujishima, Tsubasa Aoyama, Keiji Hagiwara, Satoko Mizumoto, Noriko Tanaka, Kousuke Murakami, Miho Matsumoto, Kenji Tanaka, Hironobu Sakuta
Publikováno v:
Earth, Planets and Space, Vol 73, Iss 1, Pp 1-14 (2021)
Abstract The JAXA’s Martian Moons Exploration (MMX) mission is planned to reveal the origin of Phobos and Deimos. It will remotely observe both moons and return a sample from Phobos. The nominal instruments include the TElescopic Nadir imager for G
Externí odkaz:
https://doaj.org/article/c4e88c19f1b847d7aad4d4552f740054
Autor:
Keiko Ueno, Norikazu Kiguchi, Yuka Kobayashi, Fumihiro Saika, Naoki Wakida, Chizuko Yamamoto, Takehiko Maeda, Masanobu Ozaki, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 1, Pp 47-53 (2014)
Abstract.: We previously reported that nicotine (NIC)-induced analgesia was elicited in part by activation of the endogenous opioid system. Moreover, it is well known that NIC has physical-dependence liability, but its mechanism is unclear. Therefore
Externí odkaz:
https://doaj.org/article/4fe0650f831b4635ab9ffc89eee53047
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 301-305 (2013)
Neuropathic pain, which is intolerable and persistent, arises as a direct consequence of a lesion or disease affecting the somatosensory system and can be debilitating for the affected patients. Accumulating evidence from animal studies has revealed
Externí odkaz:
https://doaj.org/article/ae00ec415fa64fdf9f891daf28f222a3
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 4, Pp 459-462 (2010)
Based on radioligand binding and signal transduction assays in our previous study, we have determined the binding pattern and functional efficacy of the constitutively active mutant N111G of angiotensin II type 1 (AT1) receptor. We have also shown th
Externí odkaz:
https://doaj.org/article/03cc0515a5584ea1a424ee948feaff04
Autor:
Mohiuddin Ahmed Bhuiyan, Murad Hossain, Shin-ichiro Miura, Takashi Nakamura, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 111, Iss 3, Pp 227-234 (2009)
The present study investigated the internalization behavior of the constitutively active mutant (CAM) N111G of angiotensin II type 1 (AT1) receptor and correlated the result with the mechanism of the constitutive activity of the mutant. The inverse a
Externí odkaz:
https://doaj.org/article/54d9fec3c01d4d6ba686265c14d4614f
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 3, Pp 341-347 (2008)
To clarify the role of peroxisome proliferator activated receptor γ (PPARγ) in neuropathic pain, we examined the effect of pioglitazone, a PPARγ agonist, on tactile allodynia and thermal hyperalgesia in a neuropathic pain model. Mice were subjecte
Externí odkaz:
https://doaj.org/article/d4baf98855f94e42b6dbaed330d4cd9e
Autor:
Habib Abul Muntasir, Murad Hossain, Mohiuddin Ahmed Bhuiyan, Tadazumi Komiyama, Takashi Nakamura, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 3, Pp 274-277 (2007)
Based on radio-ligand binding and molecular modeling studies, sarpogrelate shows a moderate selectivity for 5-HT2B versus 5-HT2A receptors. To confirm the modeling data of sarpogrelate to 5-HT2B receptors predicting interaction of sarpogrelate toward
Externí odkaz:
https://doaj.org/article/ea6f7292e4fd4e53a7f7516a8e6c17ce
Autor:
Habib Abul Muntasir, Mohiuddin Ahmed Bhuiyan, Masaji Ishiguro, Masanobu Ozaki, Takafumi Nagatomo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 189-195 (2006)
Mutations producing constitutively active G-protein coupled receptors have been found in the pathophysiology of several diseases, implying that inverse agonists at the constitutively active receptors may have preferred therapeutic applications. Becau
Externí odkaz:
https://doaj.org/article/89c41733033a43e4a3430afc5334d2c2
Autor:
Yohji Fukazawa, Takehiko Maeda, Wakako Hamabe, Kazumasa Kumamoto, Yuan Gao, Chizuko Yamamoto, Masanobu Ozaki, Shiroh Kishioka
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 408-414 (2005)
We evaluated the interaction between electroacupuncture (EA)-induced antinociception and an endogenous anti-analgesic system. EA was applied to the ST-36 acupoint for 45 min in male Sprague-Dawley rats, and pain thresholds were assessed by the hind-p
Externí odkaz:
https://doaj.org/article/9fb1a0dbad614d329ea71d7d3c9c190d