Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Masanobu Kitagawa"'
Autor:
Ayaka Asakawa, Ryoto Yoshimoto, Maki Kobayashi, Nanae Izumi, Takanori Maejima, Tsuneo Deguchi, Kazuishi Kubota, Hisashi Takahashi, Miyuki Yamada, Sachiko Ishibashi, Iichiroh Onishi, Yuko Kinowaki, Morito Kurata, Masashi Kobayashi, Hironori Ishibashi, Kenichi Okubo, Kenichi Ohashi, Masanobu Kitagawa, Kouhei Yamamoto
Publikováno v:
Cancers, Vol 16, Iss 11, p 2140 (2024)
Lung squamous cell carcinoma (LSCC) is refractory to various therapies for non-small cell cancer; therefore, new therapeutic approaches are required to improve the prognosis of LSCC. Although immunotherapies targeting B7 family molecules were explore
Externí odkaz:
https://doaj.org/article/a210ea492d8845d19080dcdbf023ee8b
Autor:
Keisuke Sugita, Iichiroh Onishi, Ran Nakayama, Sachiko Ishibashi, Masumi Ikeda, Miori Inoue, Rina Narita, Shiori Oshima, Kaho Shimizu, Shinichiro Saito, Shingo Sato, Branden S. Moriarity, Kouhei Yamamoto, David A. Largaespada, Masanobu Kitagawa, Morito Kurata
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Comprehensive screenings to clarify indirect cell–cell interactions, such as those in the tumor microenvironment, especially comprehensive assessments of supporting cells’ effects, are challenging. Therefore, in this study, indirect CRIS
Externí odkaz:
https://doaj.org/article/c2297284e9ff4fb8b4daf85b5f0dc013
Autor:
Shiori Watabe, Yukari Aruga, Ryoko Kato, Genji Kawade, Yuki Kubo, Anna Tatsuzawa, Iichiroh Onishi, Yuko Kinowaki, Sachiko Ishibashi, Masumi Ikeda, Yuki Fukawa, Keiichi Akahoshi, Minoru Tanabe, Morito Kurata, Kenichi Ohashi, Masanobu Kitagawa, Kouhei Yamamoto
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2278 (2023)
Accumulation of 4-hydroxynonenal (4-HNE), a marker of lipid peroxidation, has various favorable and unfavorable effects on cancer cells; however, the clinicopathological significance of its accumulation in hepatocellular carcinoma (HCC) and its metab
Externí odkaz:
https://doaj.org/article/b73d16ac89434a73ab5cc9b4689419f2
Autor:
Kumiko Hayashi, Daichi Nogawa, Maki Kobayashi, Ayaka Asakawa, Yae Ohata, Shota Kitagawa, Kazuishi Kubota, Hisashi Takahashi, Miyuki Yamada, Goshi Oda, Tsuyoshi Nakagawa, Hiroyuki Uetake, Iichiroh Onishi, Yuko Kinowaki, Morito Kurata, Masanobu Kitagawa, Kouhei Yamamoto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In breast cancer (BC), the development of cancer immunotherapy including immune checkpoint inhibitors has progressed. Tumor infiltrating lymphocytes (TILs) is one of the important factors for an immune response between tumor cells and immune cells in
Externí odkaz:
https://doaj.org/article/b8b61b0d2a7f4a28830d43958ef1586d
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Intravesical administration of Bacillus Calmette–Guérin (BCG) has proven useful for treatment and prevention of recurrence of superficial bladder cancer and in situ carcinoma. However, fatal side effects such as disseminated in
Externí odkaz:
https://doaj.org/article/63e0a607d76e4f0e89ac734abf862361
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 12 (2021)
Stress fractures have traditionally been classified into three categories: fatigue fractures due to overuse of bone with normal elastic resistance; insufficiency fractures due to everyday physiological stress on fragile bone with poor elastic resista
Externí odkaz:
https://doaj.org/article/4323cbe1d746454284102daf17cfd3d3
Autor:
Akiya Tatsumi, Haruka Hirakochi, Satomi Inoue, Yosuke Tanaka, Hidehiro Furuno, Masumi Ikeda, Sachiko Ishibashi, Towako Taguchi, Kouhei Yamamoto, Iichiroh Onishi, Zohar Sachs, David A. Largaespada, Masanobu Kitagawa, Morito Kurata
Publikováno v:
Biology, Vol 11, Iss 11, p 1551 (2022)
Mutations in NRAS constitutively activate cell proliferation signaling in malignant neoplasms, such as leukemia and melanoma, and the clarification of comprehensive downstream genes of NRAS might lead to the control of cell-proliferative signals of N
Externí odkaz:
https://doaj.org/article/c9febd99cf9d4275864311a1c8b8ea41
Autor:
Hajime Shinohara, Maki Kobayashi, Kumiko Hayashi, Daichi Nogawa, Ayaka Asakawa, Yae Ohata, Kazuishi Kubota, Hisashi Takahashi, Miyuki Yamada, Masanori Tokunaga, Yusuke Kinugasa, Goshi Oda, Tsuyoshi Nakagawa, Iichiroh Onishi, Yuko Kinowaki, Morito Kurata, Kenichi Ohashi, Masanobu Kitagawa, Kouhei Yamamoto
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13235 (2022)
Tumor-associated macrophages (TAMs) and abnormalities in cancer cells affect cancer progression and response to therapy. TAMs are a major component of the tumor microenvironment (TME) in breast cancer, with their invasion affecting clinical outcomes.
Externí odkaz:
https://doaj.org/article/01d6d5134c2c4f03badd26c2193538bd
Autor:
Anri Koyanagi, Iichiroh Onishi, Karin Muraoka, Ikue Sato, Shingo Sato, Tsuyoshi Kimura, Akio Kishida, Kouhei Yamamoto, Masanobu Kitagawa, Morito Kurata
Publikováno v:
Bioengineering, Vol 9, Iss 10, p 490 (2022)
Hematopoiesis is maintained by the interaction of hematopoietic stem cells (HSCs) and bone marrow mesenchymal stem cells (MSCs) in bone marrow microenvironments, called niches. Certain genetic mutations in MSCs, not HSCs, provoke some hematopoietic n
Externí odkaz:
https://doaj.org/article/2bea5e4fade64160bd52f363c575f3af
Autor:
Yosuke Tanaka, Hidetaka Kambayashi, Akiko Yamamoto, Iichiroh Onishi, Keisuke Sugita, Miwa Matsumura, Sachiko Ishibashi, Masumi Ikeda, Kouhei Yamamoto, Masanobu Kitagawa, Morito Kurata
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7723 (2022)
MYC is a major oncogene that plays an important role in cell proliferation in human cancers. Therefore, the mechanism behind MYC regulation is a viable therapeutic target for the treatment of cancer. Comprehensive and efficient screening of MYC regul
Externí odkaz:
https://doaj.org/article/83a924e38add45df903dc76792431dae