Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Masanobu, Kawakami"'
Autor:
Shunsuke Funazaki, Masashi Yoshida, Hodaka Yamada, Masafumi Kakei, Masanobu Kawakami, Shuichi Nagashima, Kazuo Hara, Katsuya Dezaki
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 1, Pp 34-41 (2022)
ABSTRACT Aims/Introduction Imeglimin is a novel oral hypoglycemic agent that improves blood glucose levels through multiple mechanisms of action including the enhancement of glucose‐stimulated insulin secretion (GSIS), however, the details of this
Externí odkaz:
https://doaj.org/article/cdbd03d228fa4020bed2960ac6e58c2b
Autor:
Hodaka Yamada, Tomio Umemoto, Masafumi Kakei, Shin-ichi Momomura, Masanobu Kawakami, San-e Ishikawa, Kazuo Hara
Publikováno v:
Nutrition & Metabolism, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Saturated fatty acids have been shown to cause insulin resistance and low-grade chronic inflammation, whereas unsaturated fatty acids suppress inflammation via G-protein coupled receptor 120 (GPR120) in macrophages. However, the a
Externí odkaz:
https://doaj.org/article/b2f425da4fb64b859b636003658682b6
Autor:
Masashi Yoshida, Masafumi Kakei, Shunsuke Funazaki, Kazuo Hara, Masanobu Kawakami, Katsuya Dezaki, Shuichi Nagashima, Hodaka Yamada
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 1, Pp 34-41 (2022)
Journal of Diabetes Investigation
Journal of Diabetes Investigation
Aims/Introduction Imeglimin is a novel oral hypoglycemic agent that improves blood glucose levels through multiple mechanisms of action including the enhancement of glucose‐stimulated insulin secretion (GSIS), however, the details of this mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429031974de2a9495267210088a29639
https://doaj.org/article/cdbd03d228fa4020bed2960ac6e58c2b
https://doaj.org/article/cdbd03d228fa4020bed2960ac6e58c2b
Autor:
Hiroto Ueba, Masashi Shiomi, Michael Brines, Michael Yamin, Tsutomu Kobayashi, Junya Ako, Shin-ichi Momomura, Anthony Cerami, Masanobu Kawakami
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 195-202 (2013)
Abstract Erythropoietin (EPO), a type I cytokine originally identified for its critical role in hematopoiesis, has been shown to have non-hematopoietic, tissue-protective effects, including suppression of atherosclerosis. However, prothrombotic effec
Externí odkaz:
https://doaj.org/article/4ae0dcabae3b4150a024adecb83217cb
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 9, Pp 1987-1992 (2012)
We have developed a simple, precise, and ultrasensitive enzymatic method for measuring serum mevalonic acid (MVA) concentration, which is thought to be a good indicator of the in vivo cholesterol biosynthesis rate. This assay is based on an enzyme cy
Externí odkaz:
https://doaj.org/article/33795fc716244f24a635c26abb8757d3
Autor:
Ayumi Ota, Akihiro Kakehashi, Fumihiko Toyoda, Nozomi Kinoshita, Machiko Shinmura, Hiroko Takano, Hiroto Obata, Takafumi Matsumoto, Junichi Tsuji, Yoh Dobashi, Wilfred Y. Fujimoto, Masanobu Kawakami, Yasunori Kanazawa
Publikováno v:
Journal of Diabetes Research, Vol 2013 (2013)
We evaluated ranirestat, an aldose reductase inhibitor, in diabetic cataract and neuropathy (DN) in spontaneously diabetic Torii (SDT) rats compared with epalrestat, the positive control. Animals were divided into groups and treated once daily with o
Externí odkaz:
https://doaj.org/article/15d49ad08e81488d95dda09702b40b9f
Autor:
Takanori Yasu, Kazunori Shimada, Nahoko Ikeda, Yoshimi Ota, Hiroyuki Sugimura, Toshikazu Funazaki, Naoki Naito, Eiichi Tokutake, Yasuhiro Endo, Minoru Wake, Yasuto Horie, Kenshiro Arao, Bonpei Takase, Shin-ichi Momomura, Masanobu Kawakami
Publikováno v:
Heart and Vessels. 32:1186-1194
This multi-center prospective non-randomized comparative study investigated the effects of pitavastatin in patients with peripheral artery disease (PAD) in terms of exercise tolerance capacities and peripheral CD34+/133+ cell numbers. At baseline, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::834be914aa6599b5ebc388c7a3b97aab
https://doi.org/10.1007/s00380-017-0988-1
https://doi.org/10.1007/s00380-017-0988-1
Autor:
Masashi Yoshida, Toshihiko Yada, Kazuo Hara, Masafumi Kakei, Kaoru Tabei, Yoshiyuki Morishita, Rina Miura, Katsuya Dezaki, Kiyonori Ito, Masanobu Kawakami, Rauza Sukma Rita, Hodaka Yamada, Susumu Ookawara
Publikováno v:
Diabetes. 66:699-709
In pancreatic β-cells, pharmacological concentrations of catecholamines, including adrenaline, have been used to inhibit insulin release and explore the multiple mechanisms involved. However, the significance of these signaling pathways for physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d605c24ee8385dad6e3c2e9a6162891b
https://doi.org/10.2337/db16-1166
https://doi.org/10.2337/db16-1166
Autor:
Yasunori Abe, Keiichi Iwanami, Mori Nakai, Masanobu Kawakami, Kenshiro Arao, Hiroshi Sekiguchi, Takaaki Mase
Publikováno v:
Internal Medicine
IgG4-related diseases (IgG4-RDs) have recently been reported in many organs other than the salivary, pancreatic and hepatobiliary systems. A 64-year-old woman was referred to our department for her abdominal fullness and cardiomegaly on chest X-ray.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1802edb73ed992a35e8af6283f558ad7
https://pubmed.ncbi.nlm.nih.gov/30626813
https://pubmed.ncbi.nlm.nih.gov/30626813
Autor:
Masanobu Kawakami, Tomoko Morita-Ohkubo, Shigehiro Katayama, Takuya Awata, Yoshimasa Aso, Toshihiko Inukai, Yuko Ohno, Natsuko Oshitani, Masafumi Matsuda, Masafumi Kakei, Yoshitaka Akiyama
Publikováno v:
Diabetology international. 8(3)
Both sitagliptin (SIT) and mitiglinide (MIT) can lower postprandial hyperglycemia. The purpose of this study was to examine differences in insulin and glucagon secretion after SIT or MIT administration when similar levels of plasma glucose (PG) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36be320bb848706791d73d93352b5115
https://pubmed.ncbi.nlm.nih.gov/30603240
https://pubmed.ncbi.nlm.nih.gov/30603240