Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Masanari Mizuta"'
Autor:
Daisuke Hidaka, Masanari Mizuta, Hiroka Sano, Sakura Nakatani, Kuniya Isobe, Yuki Narita, Sumio Hirata, Michiko Kawakami
Publikováno v:
International journal of clinical pharmacology and therapeutics. 57(5)
AIMS Serum creatinine (Cr)-derived estimated renal function indices are overestimated in elderly patients with reduced muscle mass (MM). We sought to identify equations correlated with measured glomerular filtration rate (mGFR) and assess the effect
Autor:
Wakaba Tsuchimochi, Masanari Mizuta, Hiroaki Ueno, Noboru Nakashima, Kenji Noma, Mitsuteru Fujihara, Masamitsu Nakazato, Tomomi Shiiya
Publikováno v:
Diabetes Care. 37:2024-2027
OBJECTIVE This study aimed to assess the efficacy and safety of our newly developed nasal glucagon-like peptide-1 (GLP-1) compound and injector. RESEARCH DESIGN AND METHODS Twenty-six patients with type 2 diabetes were enrolled in this double-blind p
Autor:
Shinichi Mashiba, Masamitsu Nakazato, Yukie Saitoh, Shiho Kojima, Tomomi Shiiya, Kenji Noma, Masanari Mizuta, Hiroaki Ueno
Publikováno v:
Obesity Research & Clinical Practice. 5:e335-e340
Summary Objective The benefits of fenofibrate, a peroxisome proliferator-activated receptor α agonist, against cardiovascular risk factors have been established. To clarify the underlying mechanisms of these benefits, we examined the effects of feno
Publikováno v:
Metabolism. 60:1081-1089
Glucagon-like peptide-1 (GLP-1) and angiotensin II type 1 receptor blocker reduce β-cell apoptosis in diabetes, but the underlying mechanisms are not fully understood. We examined the combination effects of GLP-1 and candesartan, an angiotensin II t
Publikováno v:
Diabetes Research and Clinical Practice. 90:54-59
Angiotensin II receptor blockers (ARBs) have been shown to decrease insulin resistance in obese diabetic animal models and reduce the risk of new-onset diabetes in hypertensive patients. In the present study, we studied whether candesartan, an ARB, c
Publikováno v:
Endocrine Journal. 54:895-902
Ghrelin is an acylated 28-amino-acid peptide that stimulates food intake, GH secretion, and gastric motility. Experimental studies have suggested that ghrelin plays roles in glucose homeostasis, atherosclerosis, and microangiopathy. We investigated p
Autor:
Masanari Mizuta
Publikováno v:
Folia Pharmacologica Japonica. 125:125-128
Publikováno v:
European Journal of Pharmacology. 458:227-234
This study aimed to investigate the effect of long-term oral nicotine administration on insulin resistance in an animal model of obesity. Eight-week-old male Zucker fatty rats (ZFRs) were administered nicotine tartrate dihydrate (4.6 mg/kg/day) in th
Publikováno v:
International Journal of Obesity. 26:318-326
AIM: To clarify the mechanism by which insulin resistance develops in obesity, Zucker fatty rats (ZFR) and lean litter mates (ZLR) were temporally subjected to oral glucose tolerance tests (OGTT) at 6 and 15 weeks of age. METHOD: As candidates for ca
Autor:
Masamitsu Nakazato, Muhtashan S. Mondal, Yukari Date, Shin-ichi Nozoe, Tomomi Shiiya, Masanari Mizuta, Shigeru Matsukura, Hiroshi Hosoda, Kenji Kangawa, Muneki Tanaka
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:240-244
Ghrelin, a novel GH-releasing peptide isolated from human and rat stomach, stimulates food intake and GH secretion. We determined plasma ghrelin concentrations in patients with simple obesity, anorexia nervosa, and type 2 diabetes mellitus by RIA. We