Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Masanari, Takamiya"'
Autor:
Martin Štefl, Masanari Takamiya, Volker Middel, Miyase Tekpınar, Karin Nienhaus, Tanja Beil, Sepand Rastegar, Uwe Strähle, Gerd Ulrich Nienhaus
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108849- (2024)
Summary: Repair of lesions in the plasma membrane is key to sustaining cellular homeostasis. Cells maintain cytoplasmic as well as membrane-bound stores of repair proteins that can rapidly precipitate at the site of membrane lesions. However, little
Externí odkaz:
https://doaj.org/article/b4511a54e95f4dbc9f67e39a510c4315
Autor:
Fushun Chen, Melina Köhler, Gokhan Cucun, Masanari Takamiya, Caghan Kizil, Mehmet Ilyas Cosacak, Sepand Rastegar
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107342- (2023)
Summary: Sox transcription factors are crucial for vertebrate nervous system development. In zebrafish embryo, sox1 genes are expressed in neural progenitor cells and neurons of ventral spinal cord. Our recent study revealed that the loss of sox1a an
Externí odkaz:
https://doaj.org/article/c4bbec29a3b347e7a5bb37768edda577
Autor:
Markus Masek, Christelle Etard, Claudia Hofmann, Andreas J. Hülsmeier, Jingjing Zang, Masanari Takamiya, Matthias Gesemann, Stephan C. F. Neuhauss, Thorsten Hornemann, Uwe Strähle, Ruxandra Bachmann-Gagescu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Here they identify a role for Bbs1 in lipid homeostasis of photoreceptor outer segments in zebrafish, which may contribute t
Externí odkaz:
https://doaj.org/article/7d1a8a9719c04d5db8028d758dd8d1e3
Autor:
Marco Hoffmann, Sven Gerlach, Masanari Takamiya, Samar Tarazi, Nils Hersch, Agnes Csiszár, Ronald Springer, Georg Dreissen, Hanno Scharr, Sepand Rastegar, Tanja Beil, Uwe Strähle, Rudolf Merkel, Bernd Hoffmann
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1210 (2023)
The efficient and biocompatible transfer of nucleic acids into mammalian cells for research applications or medical purposes is a long-standing, challenging task. Viral transduction is the most efficient transfer system, but often entails high safety
Externí odkaz:
https://doaj.org/article/09b2dbc7f9744aafa81e8f90d6398fd5
Autor:
Sergii Afonin, Oleg Babii, Aline Reuter, Volker Middel, Masanari Takamiya, Uwe Strähle, Igor V. Komarov, Anne S. Ulrich
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 39-49 (2020)
This study evaluates the embryotoxicity of dithienylethene-modified peptides upon photoswitching, using 19 analogues based on the β-hairpin scaffold of the natural membranolytic peptide gramicidin S. We established an in vivo assay in two variations
Externí odkaz:
https://doaj.org/article/48ec064feae9457a9734ef3054011ccc
Autor:
Sergii Afonin, Serhii Koniev, Laetitia Préau, Masanari Takamiya, Alexander V. Strizhak, Oleg Babii, Andrii Hrebonkin, Vasyl G. Pivovarenko, Margitta Dathe, Ferdinand le Noble, Sepand Rastegar, Uwe Strähle, Anne S. Ulrich, Igor V. Komarov
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Labeling biomolecules with fluorescent labels is an established tool for structural, biochemical, and biophysical studies; however, it remains underused for small peptides. In this work, an amino acid bearing a 3-hydroxychromone fluorophore, 2-amino-
Externí odkaz:
https://doaj.org/article/987288cc465c4e00805901d1e255fee0
Autor:
Meltem Weger, Benjamin D Weger, Andrea Schink, Masanari Takamiya, Johannes Stegmaier, Cédric Gobet, Alice Parisi, Andrei Yu Kobitski, Jonas Mertes, Nils Krone, Uwe Strähle, Gerd Ulrich Nienhaus, Ralf Mikut, Frédéric Gachon, Philipp Gut, Thomas Dickmeis
Publikováno v:
eLife, Vol 9 (2020)
The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an unexpected role of this pathway in vertebrate embryonic development. We showed that knockdown o
Externí odkaz:
https://doaj.org/article/3ce0c8c614c1482a8e39f6ec82430ce8
Autor:
Ariane Kröll‐Hermi, Frédéric Ebstein, Corinne Stoetzel, Véronique Geoffroy, Elise Schaefer, Sophie Scheidecker, Séverine Bär, Masanari Takamiya, Koichi Kawakami, Barbara A Zieba, Fouzia Studer, Valerie Pelletier, Carine Eyermann, Claude Speeg‐Schatz, Vincent Laugel, Dan Lipsker, Florian Sandron, Steven McGinn, Anne Boland, Jean‐François Deleuze, Lauriane Kuhn, Johana Chicher, Philippe Hammann, Sylvie Friant, Christelle Etard, Elke Krüger, Jean Muller, Uwe Strähle, Hélène Dollfus
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp n/a-n/a (2020)
Abstract The ubiquitin–proteasome system degrades ubiquitin‐modified proteins to maintain protein homeostasis and to control signalling. Whole‐genome sequencing of patients with severe deafness and early‐onset cataracts as part of a neurologi
Externí odkaz:
https://doaj.org/article/84cd90f8c2f147a682d5ff88f7111dd9
Autor:
Masanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D Weger, Dimitra Margariti, Angel R Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008774 (2020)
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ in the maintenance of sox10 expression, Wnt sign
Externí odkaz:
https://doaj.org/article/8e4da45e746442678c656ac1c39e9a74
Autor:
Gaoqun Zhang, Luisa Lübke, Fushun Chen, Tanja Beil, Masanari Takamiya, Nicolas Diotel, Uwe Strähle, Sepand Rastegar
Publikováno v:
Cells, Vol 10, Iss 10, p 2794 (2021)
The central nervous system of adult zebrafish displays an extraordinary neurogenic and regenerative capacity. In the zebrafish adult brain, this regenerative capacity relies on neural stem cells (NSCs) and the careful management of the NSC pool. Howe
Externí odkaz:
https://doaj.org/article/a1d476d981714cc68e578abba6cc9a1d