Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Masanari, Shiramoto"'
Autor:
Masanari Shiramoto, Tatsuya Yoshihara, Wolfgang Schmider, Hiroki Takagi, Irene Nowotny, Miyuki Kajiwara, Hideya Muto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract This study compared the pharmacokinetic and glucodynamic profiles of biosimilar SAR341402 insulin aspart to Japan-approved insulin aspart (NovoRapid) in healthy Japanese males. In this single-center, randomized, double-blind, single-dose, tw
Externí odkaz:
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects
Autor:
Yoshiaki Kirigaya, Masanari Shiramoto, Tomoko Ishizuka, Hinako Uchimaru, Shin Irie, Manabu Kato, Takako Shimizu, Takafumi Nakatsu, Yasuhiro Nishikawa, Hitoshi Ishizuka
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background To investigate the effects of coadministration of esaxerenone with amlodipine on the pharmacokinetics (PK) of each drug, and of esaxerenone on the PK of digoxin. Methods In three open-label, single-sequence, crossover studies, hea
Externí odkaz:
https://doaj.org/article/c39e71805f0e44b8b24ece08b36c520b
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 3, Pp 672-680 (2020)
Abstract Aims/Introduction Ultra‐rapid lispro (URLi) is a novel ultra‐rapid mealtime insulin. This study compared the pharmacokinetic and glucodynamic profiles, safety, and tolerability of URLi and lispro (Humalog®) in Japanese patients with typ
Externí odkaz:
https://doaj.org/article/8daafdf23073464d8fe17947034037f0
Autor:
Hirotaka Watada, Masanari Shiramoto, Shin Irie, Yasuo Terauchi, Yuichiro Yamada, Kazuhito Shiosakai, Yusuke Myobatake, Takashi Taguchi
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 1, Pp 84-93 (2019)
Abstract Aims/Introduction Pancreatic β‐cell dysfunction contributes to type 2 diabetes mellitus progression. Drugs that improve insulin secretion might be a valuable treatment approach. The present study aimed to evaluate the effect of the G prot
Externí odkaz:
https://doaj.org/article/0162078a8f384a54981915c232e5854b
Autor:
Kazuya Narushima, Hiroshi Maeda, Masanari Shiramoto, Yuichi Endo, Satoko Ohtsuka, Hiroaki Nakamura, Yoshinori Nagata, Tatsuo Uchimura, Ayako Kannami, Ryutaro Shimazaki, Masafumi Fukagawa, Tadao Akizawa
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 1, Pp 20-27 (2019)
Abstract Evocalcet is a novel calcimimetic agent for the treatment of secondary hyperparathyroidism (SHPT). This study evaluated the effects of evocalcet on inhibition and induction of cytochrome P450 (CYP) isozymes. Although drug interactions arisin
Externí odkaz:
https://doaj.org/article/1514e29883ab445f9f937630b76834da
Autor:
Peter Vink, Masanari Shiramoto, Masayuki Ogawa, Masahiro Eda, Martine Douha, Thomas Heineman, Himal Lal
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 3, Pp 574-578 (2017)
The impact of alternate routes of vaccine administration, subcutaneous (SC) or intramuscular (IM), on the safety and immunogenicity of herpes zoster subunit candidate vaccine (HZ/su) was assessed in Japanese adults aged ≥ 50 y. During this phase II
Externí odkaz:
https://doaj.org/article/237b134192944ce6ab2f2b075b5d3ac3
Autor:
Tadahiro Shinozawa, Koki Nakamura, Masanobu Shoji, Maya Morita, Maya Kimura, Hatsue Furukawa, Hiroki Ueda, Masanari Shiramoto, Kyoko Matsuguma, Yoshikazu Kaji, Ippei Ikushima, Makoto Yono, Shyh-Yuh Liou, Hirofumi Nagai, Atsushi Nakanishi, Keiji Yamamoto, Seigo Izumo
Publikováno v:
Stem Cell Reports, Vol 8, Iss 2, Pp 226-234 (2017)
To predict drug-induced serious adverse events (SAE) in clinical trials, a model using a panel of cells derived from human induced pluripotent stem cells (hiPSCs) of individuals with different susceptibilities could facilitate major advancements in t
Externí odkaz:
https://doaj.org/article/a2998877a57c406ca455ead2f82a7a50
Autor:
Hiroki Takagi, Miyuki Kajiwara, Irene Nowotny, Masanari Shiramoto, Hideya Muto, Wolfgang Schmider, Tatsuya Yoshihara
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports
This study compared the pharmacokinetic and glucodynamic profiles of biosimilar SAR341402 insulin aspart to Japan-approved insulin aspart (NovoRapid) in healthy Japanese males. In this single-center, randomized, double-blind, single-dose, two-period,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b35348be8171f6c2a176b21c9b5311
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
https://doaj.org/article/91ffc0df4bcd43f98107227aa96b64ad
Autor:
Ikumi Nakajo, Masanari Shiramoto, Hiroshi Inoue, Taiji Sawamoto, Hajimu Kurumatani, Keishi Oikawa, Masaki Inaba, Masataka Katashima
Publikováno v:
Clinical Drug Investigation. 41:549-555
Beraprost sodium (BPS), an orally administrable prostaglandin I2 derivative, is used for the treatment of chronic arterial occlusion and pulmonary arterial hypertension and has potential efficacy in nephropathy. Beraprost sustained release (beraprost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f15776084fe00209d82df28c471366
https://doi.org/10.1007/s40261-021-01031-8
https://doi.org/10.1007/s40261-021-01031-8
Pharmacokinetic interactions of esaxerenone with amlodipine and digoxin in healthy Japanese subjects
Autor:
Takafumi Nakatsu, Masanari Shiramoto, Yoshiaki Kirigaya, Takako Shimizu, Shin Irie, Tomoko Ishizuka, Yasuhiro Nishikawa, Hinako Uchimaru, Hitoshi Ishizuka, Manabu Kato
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background To investigate the effects of coadministration of esaxerenone with amlodipine on the pharmacokinetics (PK) of each drug, and of esaxerenone on the PK of digoxin. Methods In three open-label, single-sequence, crossover studies, healthy Japa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423419733856e9768cc70b02968cfc92
http://link.springer.com/article/10.1186/s40360-020-00423-4
http://link.springer.com/article/10.1186/s40360-020-00423-4