Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Masanao Sanagi"'
Autor:
Aki Shimozawa, Yuuki Fujita, Hiromi Kondo, Yu Takimoto, Makoto Terada, Masanao Sanagi, Shin-ichi Hisanaga, Masato Hasegawa
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Parkinson’s disease (PD) and related disorders are characterized by filamentous or fibrous structures consisting of abnormal α-synuclein in the brains of patients, and the distributions and spread of these pathologies are closely correlated with d
Externí odkaz:
https://doaj.org/article/398918e9ea8e4243ae5f726963d8920d
Autor:
Eiji Kurosaki, Masanao Sanagi, Hiroyuki Okumura, Hiroaki Masuzaki, Katsuhiko Gato, Kazuya Honbou, Akira Suwa, Takako Yonemoto, Tomohiko Yamaguchi, Yuko Kawasaki, Yuichi Tomura, Hirotoshi Kakuta, Tatsuya Niimi, Masaya Orita
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 349:10-20
A proportion of angiotensin II type 1 receptor blockers (ARBs) improves glucose dyshomeostasis and insulin resistance in a clinical setting. Of these ARBs, telmisartan has the unique property of being a partial agonist for peroxisome proliferator-act
Autor:
Akira Fujimori, K Terai, H Nara, Kazuhiko Mizukami, Hiroyuki Itoh, Masamichi Okada, Masanao Sanagi, Koji Takakura, Shinji Fukushima
Publikováno v:
British Journal of Pharmacology. 156:1267-1278
Background and purpose: Various complications consequent on disordered calcium and phosphate homeostasis occur frequently in chronic kidney disease (CKD) patients. Particularly, vascular calcification has high morbidity and mortality rates. There is
Autor:
Takashi Miyauchi, Katsutoshi Goto, Satoshi Sakai, Masanao Sanagi, Katsumi Sudoh, Iwao Yamaguchi, Motoyuki Iemitsu, Akira Fujimori, Hironori Yuyama, Hisataka Shikama
Publikováno v:
Journal of Cardiovascular Pharmacology. 44:S354-S357
The effects of the novel, selective endothelin-A (ET A ) receptor antagonist YM598 on both-side heart failure were investigated. Right-side heart failure secondary to pulmonary hypertension was produced by a single subcutaneous injection of 60 mg/kg
Autor:
Masao Sasamata, Akiko Koakutsu, Keiji Miyata, Akira Fujimori, Katsumi Sudoh, Masanao Sanagi, Hironori Yuyama
Publikováno v:
European Journal of Pharmacology. 496:129-139
We investigated the preventive and therapeutic effects of the selective endothelin ETA receptor antagonist potassium(E)-N-[6-methoxy-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]-2-phenylenthenesulfonamidate (YM598) on the development of pul
Autor:
Akira Fujimori, Kazumi Hayashi, Osamu Inagaki, Takeyuki Yatsu, Yuichi Tomura, Masayuki Tanahashi, Masanao Sanagi
Publikováno v:
Pharmacological Research. 47:243-252
Several factors such as proteinuria and renal fibrosis may be important in the progression of many forms of chronic renal diseases. The purposes of the current study were to investigate the progressive renal failure of the rats with surgical renal ma
Autor:
Masashi Ukai, Shuichi Sato, Masanao Sanagi, Akiyoshi Ohtake, Akiko Koakutsu, Keiji Miyata, Katsumi Sudoh, Masao Sasamata, Akira Fujimori, Hironori Yuyama
Publikováno v:
European journal of pharmacology. 580(3)
We investigated the contractile response of the lower urinary tract to endothelin-1 in vitro (rabbits) and in vivo (dogs). We also assessed the effects of a selective endothelin ETA receptor antagonist, (E)-N-[6-methoxy-5-(2-methoxyphenoxy)[2, 2′-b
Autor:
Masanao Sanagi, Keiji Miyata, Masao Sasamata, Yukiko Noguchi, Akira Fujimori, Katsumi Sudoh, Hironori Yuyama, Akiko Koakutsu
Publikováno v:
Vascular pharmacology. 43(1)
The preventive effects of the novel and selective endothelin ET(A) receptor antagonist YM598 on the development of pulmonary hypertension (PH) were investigated in chronic hypoxia-induced PH rats. Oral administration of YM598 at a dose of 1 mg/kg was
Autor:
Masanao Sanagi, Keiji Miyata, Hironori Yuyama, Katsumi Sudoh, Akiko Koakutsu, Akira Fujimori, Mikiko Yamanouchi Pharmaceutical Co. Ltd. Mori, Hironori Harada
Publikováno v:
European journal of pharmacology. 478(1)
We describe here the pharmacology of (E)-N-[6-methoxy-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-2-phenylethenesulfonamide monopotassium salt (YM598), a novel selective endothelin ET(A) receptor antagonist synthesized through the modification of th
Autor:
Diana C. Grootendorst, James Fotheringham, Kazuhiro Shiizaki, Mamika Nishida, Sara Beati, Natalia Grinblat, Martin Wilkie, Christiane Drechsler, Eva Jakopin, Sándor Túri, Ichiei Narita, Masahide Mizobuchi, Viktor Gromiko, Ahmet Kahraman, Padmini Manghat, Kosaku Nitta, Fumihoko Koiwa, Nobuaki Uno, Mehmet Kanbay, Koji Takaori, Sebastjan Bevc, Guillaume Jean, Koji Usui, Atsuo Tanaka, E Mantuano, Massimiliano Migliori, Juan Carlos Santos, Kikuo Okada, Clorinda De Rosa, Hiroaki Ogata, Valerie Pilotovich, Kazuharu Uchida, Pasquale Libutti, Carlo Lomonte, Maurizio Gallieni, Jorge Shehadi, Anzu Tanaka, Yumi Shinbo, Jacob Hofman-Bang, Robert Bell, Motoko Tanaka, Giancarlo Betti, Chong Myung Kang, Hiromi Nara, Vera Krane, Carina Ferreira, Adrian Covic, Shingo Fukuma, Masako Furutani, Aiji Yajima, Vasilis Filiopoulos, Akira Onishi, Zhihua Zheng, Sandor Vido, Yoshihiko Watarai, Charles Chazot, Aníbal Ferreira, Teruhiko Totani, Fatih Ates, Giada Bernabini, Christoph Wanner, Kanji Shishido, Satoko Yamamoto, Alberto Rosati, Chiaki Kumata, Tomoko Kawanishi, Ikuji Hatamura, Keiko Uchida, Junichiro James Kazama, Mariko Ochiai, Mark Hill, Hiroyuki Ito, Eiji Kusano, Djamal Berbiche, Marcela Fabiana Gianfelici, Serap Demir, Friedo W. Dekker, Kazuhiro Terai, Elisabeth Boeschoten, Chikako Takaeda, Giovanni Manca Rizza, Keita Mori, Akira Fujimori, Diego Brancaccio, Breda Pecovnik Balon, Chee Kay Cheung, Chang Hwa Lee, Fumiko Kojima, Natalia Karlovich, Jaber Zaidan, Susumu Matsuoka, Olivia Turri, José Cortez, Nabieh Al-Hilali, Eriko Kinugasa, Tokunori Tsuzuki, Polyxeni Metaxaki, Baldomero Romero, Akihide Tokumoto, David Goldsmith, Domenico Chimienti, Naoki Hamaguchi, Imre Kulcsar, Masanao Sanagi, Annalisa Teutonico, Riccardo Giusti, Naser Hussain, Dimosthenis Vlassopoulos, Hirotaka Komaba, Bak Leong Goh, Shioko Okada, Geeta Hampson, Josefina Susana Lossi, Célia Gil, Erzsébet Ladányi, Masa Knehtl, Pietro Ravani, Akemi Ito, Takahisa Hiramitsu, Ellie Asgari, Akiko Takeshima, Yoh Terada, Carlo Basile, Bassam Al-Helal, Karl Winkler, Isis Cerezo, Tetsuhiko Sato, Yi Huang, Serge Cournoyer, Ignac Fogelmann, Theodora Micha, Barney Harrison, Ioannis Karatzas, Eberhard Ritz, Sabrina Paoletti, Shunichiro Hachiya, Valentina Marchetti, Joon Sung Park, Indarte Laura, Fabio Malberti, Tetsuya Oishi, Tetsuya Ogawa, Norihisa Takasugi, Giuliano Barsotti, Pablo Federico Nasca, Masafumi Fukagawa, Tadao Akizawa, Csaba Bereczki, Cristina Jorge, Xiaohua Wang, Csaba Ambrus, Noriaki Yorioka, Ayumu Nakashima, Raymond T. Krediet, Shigeru Otsubo, Fumie Saji, Takafumi Akabane, Juan Villa, Andrea Bruno, Mingliang Hu, József Balla, Inês Aires, Kenichiro Shigemoto, Amal Hassan, Kirill Komissarov, Christopher Thiam Seong Lim, Keiko Takahashi, Eva Kiss, Roberto Bigazzi, Mario Cozzolino, Klaus Olgaard, James England, Yoshihiro Tominaga, Toru Kawai, Kazuya Takasawa, Savino Cocola, Winfried März, Katsuyuki Tome, Keiji Shimazu, Takaharu Nagasaka, Masaaki Inaba, Ewa Lewin, Yoshiki Nishizawa, Marília Borges, Manabu Ogura, Seitaro Mutoh, Anthony Wierzbicki, Shohei Nakanishi, Maurizio Antonelli, Tülay Köken, Vincenzo Panichi, Kensuke Nishiguchi, Maksimiljan Gorenjak, Tiago Amaral, Hyunchul Kim, Yoshiko Takanak, Makoto Sakai, Eriko Eguchi, Macroui Sonikian, Gheun-Ho Kim, Xueqing Yu, Mohammed Al-Azmi, Maria Luisa Biondi, Giovanni Grazi, Yaser Abdul Kawi, Andrea Galassi, Sunil Bhandari, Ali Akcay, Antonio Bellasi, Masao Koshikawa, Sandra del Carmen Reinoso, Rosa Macias, Eiko Nakazawa, Mylene Fagnan, Takashi Kuwahara, Patrícia Matias, Botond Csiky, Norihiko Goto, A.N. Hisham, Soshi Yorifuji, Yuko Watanabe, Yan Lei, Francisco Caravaca, Yudisthra M. Ganeshadeva, Shinji Fukushima
Publikováno v:
NDT Plus. 2:ii2065-ii2065