Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Masanao, Saio"'
Autor:
Tamaki Hiroe, Shunichi Moriya, Sayaka Kobayashi, Yoshimi Nishijima, Akira Watanabe, Ken Shirabe, Hayato Ikota, Hideaki Yokoo, Masanao Saio
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Background: The nuclear laminar protein Lamin A and inner nuclear membrane protein Emerin plays important role in sustaining nuclear structure. However, They have not investigated the significance of these proteins for development of pancreatic intra
Externí odkaz:
https://doaj.org/article/aba9dfabcb7848ff87e727f84dd40653
Autor:
Eiichi Ogawa, Atsushi Tanaka, Kenichi Harada, Hiroshi Yatsuhashi, Kazumoto Murata, Masamichi Kimura, Jun Imamura, Masanao Saio, Yoshihiro Ikura, Kouichi Miura, Ichiro Ieiri, Kiminori Kimura
Publikováno v:
BMJ Open Gastroenterology, Vol 9, Iss 1 (2022)
Objective This study aimed to evaluate the safety and tolerability of OP-724, a CREB-binding protein/β-catenin inhibitor, in patients with advanced primary biliary cholangitis (PBC).Design An open-label, non-randomised, phase 1 trial was conducted a
Externí odkaz:
https://doaj.org/article/cabfe85f53b94df4a8a96a71c3bfa66f
Autor:
Kiminori Kimura, Tatsuya Kanto, Shinji Shimoda, Kenichi Harada, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Eiichi Ogawa, Masanao Saio, Yoshihiro Ikura, Takuji Okusaka, Kazuaki Inoue, Tetsuya Ishikawa, Ichiro Ieiri, Junji Kishimoto, Koji Todaka, Terumi Kamisawa
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104069- (2022)
Summary: Background: We conducted an exploratory study to assess the safety tolerability, and anti-fibrotic effects of PRI-724, a CBP/β-catenin inhibitor, in patients with hepatitis C virus (HCV)- and hepatitis B virus (HBV)-induced cirrhosis. Metho
Externí odkaz:
https://doaj.org/article/a68a8544980a4b5a8162b15098cfe871
Autor:
Batchimeg Tsedenbal, Tomomi Yoshida, Bayarmaa Enkhbat, Uyanga Gotov, Enkhtuya Sharkhuu, Masanao Saio, Toshio Fukuda
Publikováno v:
International Journal of Infectious Diseases, Vol 77, Iss , Pp 8-13 (2018)
Objectives: Few studies on human papillomavirus (HPV) have been conducted in Mongolia. This study was performed to evaluate the prevalent HPV genotypes and their associations with cytology and demographic and behavioral characteristics in Mongolian w
Externí odkaz:
https://doaj.org/article/13f83ef4c7e145bfbfb6db29a363c2ef
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 23:4099-4107
Mongolia is a sparsely populated country; however, almost fifty percent of the population lives in the capital city. Medical care services and exceptionally well-organized cervical cancer screening tests are limited in remote areas. To improve cervic
Autor:
Yui Mukade, Sayaka Kobayashi, Yoshimi Nishijima, Kiminori Kimura, Akira Watanabe, Hayato Ikota, Ken Shirabe, Hideaki Yokoo, Masanao Saio
Publikováno v:
Journal of Histochemistry & Cytochemistry. 71:11-26
We tried to prevent nonspecific nuclear staining (NS-NS) of picrosirius red (PSR) staining by treating the specimens with one of the heteropoly acids phosphotungstic acid (PTA). We analyzed a total of 35 cases of non-cancerous liver tissue for fibros
Autor:
Kiminori Kimura, Akemi Ikoma, Maki Shibakawa, Shinji Shimoda, Kenichi Harada, Masanao Saio, Jun Imamura, Yosuke Osawa, Masamichi Kimura, Koji Nishikawa, Takuji Okusaka, Satoshi Morita, Kazuaki Inoue, Tatsuya Kanto, Koji Todaka, Yoichi Nakanishi, Michinori Kohara, Masashi Mizokami
Publikováno v:
EBioMedicine, Vol 23, Iss C, Pp 79-87 (2017)
Background: There is currently no anti-fibrotic drug therapy available to treat hepatitis C virus (HCV) cirrhosis. The aim of this study was to assess the safety, tolerability, and anti-fibrotic effect of PRI-724, a small-molecule modulator of Wnt si
Externí odkaz:
https://doaj.org/article/17a6c1e0f18841c184e14890ad5fd895
Autor:
Shohei Tsuji, Shinsuke Nakamura, Takashi Maoka, Tetsuya Yamada, Takahiko Imai, Takuya Ohba, Tomohiro Yako, Masahiro Hayashi, Ken Endo, Masanao Saio, Hideaki Hara, Masamitsu Shimazawa
Publikováno v:
Marine Drugs, Vol 18, Iss 9, p 474 (2020)
Several antitumour drugs have been isolated from natural products and many clinical trials are underway to evaluate their potential. There have been numerous reports about the antitumour effects of astaxanthin against several tumours but no studies i
Externí odkaz:
https://doaj.org/article/89d481365e5f467787ec192cd45870cf
Autor:
Miduki Ouchi, Sayaka Kobayashi, Yoshimi Nishijima, Naoki Inoue, Hayato Ikota, Akira Iwase, Hideaki Yokoo, Masanao Saio
Publikováno v:
Pathology - Research and Practice. 247:154560
Autor:
Sayaka Kobayashi, Shunichi Moriya, Hideaki Yokoo, Masanao Saio, Yoshimi Nishijima, Hayato Ikota, Midori Suzuki, Takaaki Fujii
Publikováno v:
Cytopathology. 32:718-731
OBJECTIVE The morphological features of nuclei in cytological and histological specimens were compared and examined for the presence of BRAFV600E mutation and the appearance rate of intranuclear cytoplasmic inclusions (NI). METHODS BRAFV600E mutation