Výsledky vyhledávání - "Masamitsu Nakayama"

Akademický článek

Physical Characteristics of von Willebrand Factor Binding with Platelet Glycoprotein Ibɑ Mutants at Residue 233 Causing Various Biological Functions

Autor: Masamitsu Nakayama, Shinichi Goto, Shinya Goto

Publikováno v: TH Open, Vol 06, Iss 04, Pp e421-e428 (2022)

Glycoprotein (GP: HIS1-PRO265) Ibɑ is a receptor protein expressed on the surface of the platelet. Its N-terminus domain binds with the A1 domain (ASP1269-PRO1472) of its ligand protein von Willebrand factor (VWF) and plays a unique role in platelet

Externí odkaz: https://doaj.org/article/7cf1311085454445ab88efc5be2944c8

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Different Physical Parameters in the Bonds between Platelet Glycoprotein Ibalpha with von Willebrand factor and with Coagulant Factor XI -Results from the Molecular Dynamic Simulation

Autor: Masamitsu Nakayama, Shinichi Goto, Satoko Takemoto, Hideki Oka, Hideo Yokota, Shu Takagi, Shinya Goto

Background: Both von Willebrand factor (VWF) and coagulation factor XI (FXI) bind with platelet membrane glycoprotein (GP) Ibalpha. However, the differences in the physical parameters in the bonds between VWF-GPIbalpha and FXI-GPIbalpha mediating dif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47fd393be6c272da6755a1de10093217
https://doi.org/10.1101/2023.04.16.534191

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Effects of caplacizumab, a specific inhibitor of the A1 domain of von Willebrand factor binding with platelet membrane glycoprotein (GP) Ibα, on the length of platelet pseudopods supporting platelet adhesions on immobilized von Willebrand factor under blood flow condition

Autor: Masamitsu Nakayama, Shinichi Goto, Shinya Goto

Publikováno v: Journal of Biorheology. 36:68-75

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a75168dc23ec6d805431c6150b707e6
https://doi.org/10.17106/jbr.36.68

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Integrated Computer Simulation Model of the Dynamic Conformational Motion of Intracellular, Transmembrane, and Extracellular Domain of Platelet Integrin α IIbβ 3 (Platelet Membrane Glycoprotein: GPIIb-IIIa)

Autor: Masamitsu Nakayama, Shinichi Goto, Shinya Goto

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f50b8219fe29d14e10f0889e0e4139f5
https://doi.org/10.2139/ssrn.4234528

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Important Regulatory Roles of Erythrocytes in Platelet Adhesion to the von Willebrand Factor on the Wall under Blood Flow Conditions

Autor: Noriko Tamura, Masamitsu Nakayama, Seiji Shiozaki, Kazuyasu Sugiyama, Shinya Goto, Shu Takagi, Kazuya Shimizu, Shinichi Goto

Publikováno v: Thrombosis and haemostasis. 122(6)

The role of erythrocytes in platelet adhesion to von Willebrand factor (VWF) on the vessel wall through their membrane glycoprotein (GP)Ibα under blood flow conditions has not yet been elucidated. Blood specimens containing fluorescent-labeled plate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9896df6cecd7814f5083c3e30c3fc8b
https://pubmed.ncbi.nlm.nih.gov/34695874

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Potential different impact of inhibition of thrombin function and thrombin generation rate for the growth of thrombi formed at site of endothelial injury under blood flow condition

Autor: Masamitsu Nakayama, Shu Takagi, Hideo Yokota, Shinya Goto, Terumitsu Hasebe, Aiko Tomita, Shinichi Goto, Kengo Ayabe, Hiroto Yabushita, Hideki Oka

Publikováno v: Thrombosis research. 179

Introduction Thrombin inhibitor and anti-Xa are now widely used in clinical practice. However, the difference between thrombin inhibitor and anti-Xa in prevention of thrombosis is still to be elucidated. Materials and methods Computer simulator imple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c56ae847b36a33fa19b8cb3daa9338
https://pubmed.ncbi.nlm.nih.gov/31129447

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Synthesis of Thermoplastic Poly(2‐methoxyethyl acrylate)‐Based Polyurethane by RAFT and Condensation Polymerization

Autor: Tomoki Maeda, Atsushi Hotta, Masamitsu Nakayama, Shunsuke Tazawa

Publikováno v: Macromolecular Rapid Communications. 41:2000346

Thermoplastic solid poly(2-methoxyethyl acrylate) (PMEA)-based polyurethane (PU) is synthesized through the reversible addition-fragmentation chain transfer (RAFT) polymerization and the condensation polymerization, using hydroxyl-terminated RAFT rea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2316aa06aa9a8e995426be24614c642
https://doi.org/10.1002/marc.202000346

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In vitro and in vivo tests of nanoporous membrane coated with biocompatible fluorine-doped diamond-like carbon for hemofiltration treatment

Autor: Yoshihiko Kanno, Tetsuya Suzuki, Masamitsu Nakayama, Norihisa Miki, Takashi Ota

Publikováno v: 2018 IEEE Micro Electro Mechanical Systems (MEMS).

In this report, we experimentally investigated the blood hemofiltration capacity of a nanoporous dialysis membrane (poly(ether sulfone), PES) whose surface was modified with fluorine-doped diamond-like carbon(f-DLC). Surface modification of the nanop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea1494b4586b35a037f9d8b7a6bdcc2f
https://doi.org/10.1109/memsys.2018.8346575

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