Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Masamitsu, Iino"'
Autor:
Nami Kitajima, Kenji Takikawa, Hiroshi Sekiya, Kaname Satoh, Daisuke Asanuma, Hirokazu Sakamoto, Shodai Takahashi, Kenjiro Hanaoka, Yasuteru Urano, Shigeyuki Namiki, Masamitsu Iino, Kenzo Hirose
Publikováno v:
eLife, Vol 9 (2020)
Adenosine 5’ triphosphate (ATP) is a ubiquitous extracellular signaling messenger. Here, we describe a method for in-vivo imaging of extracellular ATP with high spatiotemporal resolution. We prepared a comprehensive set of cysteine-substitution mut
Externí odkaz:
https://doaj.org/article/7770e7ad2819423189c5155516e8341c
Autor:
Yoshinori Mikami, Kazunori Kanemaru, Yohei Okubo, Takuya Nakaune, Junji Suzuki, Kazuki Shibata, Hiroki Sugiyama, Ryuta Koyama, Takashi Murayama, Akihiro Ito, Toshiko Yamazawa, Yuji Ikegaya, Takashi Sakurai, Nobuhito Saito, Sho Kakizawa, Masamitsu Iino
Publikováno v:
EBioMedicine, Vol 11, Iss C, Pp 253-261 (2016)
Status epilepticus (SE) is a life-threatening emergency that can cause neurodegeneration with debilitating neurological disorders. However, the mechanism by which convulsive SE results in neurodegeneration is not fully understood. It has been shown t
Externí odkaz:
https://doaj.org/article/ea52f55544544cf79c3de1717443b0c8
Publikováno v:
Cell Reports, Vol 12, Iss 12, Pp 1951-1959 (2015)
Schwann cells (SCs) myelinate peripheral neurons to promote the rapid conduction of action potentials, and the process of myelination is known to be regulated by signals from axons to SCs. Given that SC mitochondria are one of the potential regulator
Externí odkaz:
https://doaj.org/article/1af603adbd4648638c22ab99308096d2
Autor:
Enrico, Zampese, David L, Wokosin, Patricia, Gonzalez-Rodriguez, Jaime N, Guzman, Tatiana, Tkatch, Jyothisri, Kondapalli, William C, Surmeier, Karis B, D'Alessandro, Diego, De Stefani, Rosario, Rizzuto, Masamitsu, Iino, Jeffery D, Molkentin, Navdeep S, Chandel, Paul T, Schumacker, D James, Surmeier
Publikováno v:
Science advances. 8(39)
How do neurons match generation of adenosine triphosphate by mitochondria to the bioenergetic demands of regenerative activity? Although the subject of speculation, this coupling is still poorly understood, particularly in neurons that are tonically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::585c2e07083b4d0136f56ffe55a7cff7
https://pubmed.ncbi.nlm.nih.gov/36179023
https://pubmed.ncbi.nlm.nih.gov/36179023
Autor:
Kazunori Kanemaru, Hiroshi Sekiya, Ming Xu, Kaname Satoh, Nami Kitajima, Keitaro Yoshida, Yohei Okubo, Takuya Sasaki, Satoru Moritoh, Hidetoshi Hasuwa, Masaru Mimura, Kazuki Horikawa, Ko Matsui, Takeharu Nagai, Masamitsu Iino, Kenji F. Tanaka
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 311-318 (2014)
Astrocytes generate local calcium (Ca2+) signals that are thought to regulate their functions. Visualization of these signals in the intact brain requires an imaging method with high spatiotemporal resolution. Here, we describe such a method using tr
Externí odkaz:
https://doaj.org/article/9c3a6ad1f25944a786f8b1db0e674d19
Autor:
Nagomi Kurebayashi, Takashi Murayama, Ryosaku Ota, Junji Suzuki, Kazunori Kanemaru, Takuya Kobayashi, Seiko Ohno, Minoru Horie, Masamitsu Iino, Fumiyoshi Yamashita, Takashi Sakurai
Publikováno v:
Journal of General Physiology. 154
Type 2 ryanodine receptor (RYR2) is a cardiac Ca2+ release channel in the ER. Mutations in RYR2 are linked to catecholaminergic polymorphic ventricular tachycardia (CPVT). CPVT is associated with enhanced spontaneous Ca2+ release, which tends to occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feae2d08fac1ad00bd6ab71a160804de
https://doi.org/10.1085/jgp.202112869
https://doi.org/10.1085/jgp.202112869
Publikováno v:
Biochemical and Biophysical Research Communications. 522:1003-1008
Astrocytes regulate various brain functions, for which Ca2+ release from the endoplasmic reticulum (ER) often play crucial roles. Because astrocytic ER Ca2+ release is robust and frequent, the ER Ca2+ refilling mechanism should be critical for ongoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6e537b9fe783ced744c670fefa6018c
https://doi.org/10.1016/j.bbrc.2019.12.006
https://doi.org/10.1016/j.bbrc.2019.12.006
Autor:
Yasuteru Urano, Kenjiro Hanaoka, Takayuki Ikeno, Yohei Okubo, Shodai Takahashi, Masamitsu Iino, Tasuku Ueno, Tetsuo Nagano, Honami Echizen, Kenzo Hirose, Toru Komatsu
Publikováno v:
Chemistry – An Asian Journal. 15:524-530
Fluorescence imaging in the near-infrared (NIR) region (650-900 nm) is useful for bioimaging because background autofluorescence is low and tissue penetration is high in this range. In addition, NIR fluorescence is useful as a complementary color win
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b938d272226d739eb503ac75d7e0822c
https://doi.org/10.1002/asia.201901689
https://doi.org/10.1002/asia.201901689
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-10 (2009)
Abstract Genetically identical cells in a uniform external environment can exhibit different phenotypes, which are often masked by conventional measurements that average over cell populations. Although most studies on this topic have used microorgani
Externí odkaz:
https://doaj.org/article/f314702c27ef41c6ba5de55fe2c71d31
Autor:
Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130606 (2015)
The type 1 ryanodine receptor (RyR1) is a Ca2+ release channel in the sarcoplasmic reticulum of skeletal muscle and is mutated in several diseases, including malignant hyperthermia (MH) and central core disease (CCD). Most MH and CCD mutations cause
Externí odkaz:
https://doaj.org/article/88d97002050e480fa564611f31168c05