Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Masamitsu, Honma"'
Autor:
Shigeharu Muto, Ayako Furuhama, Mika Yamamoto, Yasuteru Otagiri, Naoki Koyama, Seiji Hitaoka, Yusuke Nagato, Hirofumi Ouchi, Masahiro Ogawa, Kisako Shikano, Katsuya Yamada, Satoshi Ono, Minami Hoki, Fumiya Ishizuka, Soichiro Hagio, Chiaki Takeshita, Hisayoshi Omori, Kiyohiro Hashimoto, Satsuki Chikura, Masamitsu Honma, Kei-ichi Sugiyama, Masayuki Mishima
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-10 (2024)
Abstract Background Primary aromatic amines (PAAs) present significant challenges in the prediction of mutagenicity using current standard quantitative structure activity relationship (QSAR) systems, which are knowledge-based and statistics-based, be
Externí odkaz:
https://doaj.org/article/3b431e34936344f28473dfc085ece5fa
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-10 (2023)
Abstract Background Carcinogenic risk assessment studies have been repeatedly improved and are still being debated to find a goal. Evaluation might be changed if new approaches would be applied to some chemicals which means that new approaches may ch
Externí odkaz:
https://doaj.org/article/b42c2d763fe24571991782f598b59fc7
Publikováno v:
Genes and Environment, Vol 45, Iss 1, Pp 1-8 (2023)
Abstract Background Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment. Metabolic enzymes activate multip
Externí odkaz:
https://doaj.org/article/b5e3715d87a846bc99e3c5ba6095b4c1
Autor:
Katsuyoshi Horibata, Hironao Takasawa, Motoki Hojo, Yuhji Taquahashi, Miyuki Shigano, Satoshi Yokota, Norihiro Kobayashi, Kei-ichi Sugiyama, Masamitsu Honma, Shuichi Hamada
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-7 (2022)
Abstract Background Multiwalled carbon nanotubes (MWCNTs) are suspected lung carcinogens because their shape and size are similar to asbestos. Various MWCNT types are manufactured; however, only MWNT-7 is classified into Group 2B by The International
Externí odkaz:
https://doaj.org/article/fc3775cf014146ff9ba06feb5dab0149
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-8 (2022)
Abstract Bisphenol-A (BPA) is an important environmental contaminant with adverse health effects suspected to be mediated through epigenetic mechanisms. We had reported that the FLO1-dependent flocculation of transgenic yeast expressing human DNA met
Externí odkaz:
https://doaj.org/article/521c13294ad5492dac496d7ca3478b66
Autor:
Maiko Watanabe, Takahiro Ohnishi, Sakura Arai, Tsuyoshi Kawakami, Katsuhiko Hayashi, Kenji Ohya, Shouhei Hirose, Tomoya Yoshinari, Satoshi Taharaguchi, Hirohisa Mekata, Takahide Taniguchi, Yoshiaki Ikarashi, Masamitsu Honma, Yukihiro Goda, Yukiko Hara-Kudo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Aerosols or saliva containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can contaminate living environments, and viruses can be indirectly transmitted. To understand the survival potential of the virus, the viral titers of
Externí odkaz:
https://doaj.org/article/88bba7dcb1134a309f834e4d349099d3
Autor:
Masamitsu Honma, Masami Yamada, Manabu Yasui, Katsuyoshi Horibata, Kei-ichi Sugiyama, Kenichi Masumura
Publikováno v:
Toxicology Reports, Vol 9, Iss , Pp 1008-1012 (2022)
We assessed the genotoxicity of 30 food-flavoring chemicals used in Japan that have not been investigated before. These 30 food-flavoring chemicals have representative chemical structures belonging to 18 chemical classes. The Ames and chromosomal abe
Externí odkaz:
https://doaj.org/article/a98a2a9440d34653b535ac6b9080afb8
Autor:
Kenichi Masumura, Tomoko Ando, Naomi Toyoda-Hokaiwado, Akiko Ukai, Takehiko Nohmi, Masamitsu Honma
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-9 (2021)
Abstract Background Gene mutations induced in germ cells may be transmitted to the next generation and cause adverse effects such as genetic diseases. Certain mutations may result in infertility or death in early development. Thus, the mutations may
Externí odkaz:
https://doaj.org/article/5725258da4f744ebbf724e0bd97f4b54
Autor:
Masamitsu Honma, Masami Yamada, Manabu Yasui, Katsuyoshi Horibata, Kei-ichi Sugiyama, Kenichi Masumura
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-11 (2021)
Abstract Background Perillaldehyde and cinnamaldehyde are natural substances found in plants that are used as flavoring ingredients. Due to the α,β-unsaturated aldehydes in their structures, these compounds are expected to be DNA reactive. Indeed,
Externí odkaz:
https://doaj.org/article/606c347fbcb44d078b3a17dea5f712a6
Autor:
Kenichi Masumura, Tomoko Ando, Akiko Ukai, Sho Fujiwara, Shigeo Yokose, Xinyue You, Takayoshi Suzuki, Hiroyuki Hayashi, Takehiko Nohmi, Hisayoshi Takagi, Masamitsu Honma
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-12 (2021)
Abstract Background Gene mutation assays in transgenic rodents are useful tools to investigate in vivo mutagenicity in a target tissue. Using a lambda EG10 transgene containing reporter genes, gpt delta transgenic mice and rats have been developed to
Externí odkaz:
https://doaj.org/article/d36d5fcbf94e4113beef74e2f5e7d3f1