Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Masamichi Shinoda"'
Autor:
Chihiro Soma, Suzuro Hitomi, Eri Oshima, Yoshinori Hayashi, Kumi Soma, Ikuko Shibuta, Yoshiyuki Tsuboi, Tetsuo Shirakawa, Takashi Kikuiri, Koichi Iwata, Masamichi Shinoda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Patients with persistent pain have sometimes history of physical abuse or neglect during infancy. However, the pathogenic mechanisms underlying orofacial pain hypersensitivity associated with early-life stress remain unclear. The present stu
Externí odkaz:
https://doaj.org/article/ede59f5bf7d34c8791c55e143b381b9c
Autor:
Eri Oshima, Yoshinori Hayashi, Zhen Xie, Hitoshi Sato, Suzuro Hitomi, Ikuko Shibuta, Kentaro Urata, Junjun Ni, Koichi Iwata, Tatsuo Shirota, Masamichi Shinoda
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Although peripheral nerves have an intrinsic self-repair capacity following damage, functional recovery is limited in patients. It is a well-established fact that macrophages accumulate at the site of injury. Numerous studies indi
Externí odkaz:
https://doaj.org/article/51311b5ea36c44da9afd4dfd3265e671
Autor:
Masato Iida, Suzuro Hitomi, Yoshinori Hayashi, Ikuko Shibuta, Yoshiyuki Tsuboi, Koichiro Ueda, Koichi Iwata, Masamichi Shinoda
Publikováno v:
Brain Research Bulletin, Vol 206, Iss , Pp 110844- (2024)
Oral ulcerative mucositis (OUM) induces severe pain, leading to a low quality of life. Linalool odor exposure has recently been reported to suppress inflammatory pain in the hind paws. However, the analgesic effect of linalool odor on orofacial pain
Externí odkaz:
https://doaj.org/article/75b8c7fc7bce4c3497d996be3470493b
Autor:
Ko Ito, Masamichi Shinoda, Kumi Soma, Daisuke Ikutame, Eiji Ikami, Yosuke Mizuno, Michihiko Usui, Seiji Asoda, Tsuyoshi Sato
Publikováno v:
Stresses, Vol 3, Iss 1, Pp 58-68 (2022)
(1) Background: Chronic psychosocial stress can lead to oral dysesthesia with tongue pain. We examined whether psychosocial stress causes orofacial pain, and analyzed the comprehensive gene expression patterns of circulating cells and transient recep
Externí odkaz:
https://doaj.org/article/f5917bb2887f4d0795ffbb54b1d2dc41
Autor:
Jo Otsuji, Yoshinori Hayashi, Suzuro Hitomi, Chihiro Soma, Kumi Soma, Ikuko Shibuta, Koichi Iwata, Tetsuo Shirakawa, Masamichi Shinoda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Whisker pad skin incision in infancy causes the prolongation of mechanical allodynia after re-incision in adulthood. A recent study also proposed the importance of sex differences in pain signaling in the spinal cord. However, the sex differ
Externí odkaz:
https://doaj.org/article/c9128e55d23a4fb3b11ebe98b2916d88
Autor:
Yoshinori Hayashi, Jo Otsuji, Eri Oshima, Suzuro Hitomi, Junjun Ni, Kentaro Urata, Ikuko Shibuta, Koichi Iwata, Masamichi Shinoda
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100622- (2023)
The dysfunction of descending noradrenergic (NAergic) modulation in second-order neurons has long been observed in neuropathic pain. In clinical practice, antidepressants that increase noradrenaline levels in the synaptic cleft are used as first-line
Externí odkaz:
https://doaj.org/article/d9ffb4c65f854ee8bd33679bc1f42ab4
Autor:
Suzuro Hitomi, Tomotaka Nodai, Shoichiro Kokabu, Takemi Shikayama, Misa Sago-Ito, Chihiro Nakatomi, Kiyoshi Terawaki, Yuji Omiya, Masamichi Shinoda, Kentaro Ono
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284617 (2023)
Severe intraoral pain induces difficulty in eating and speaking, leading to a decline in the quality of life. However, the molecular mechanisms underlying intraoral pain remain unclear. Here, we investigated gene modulation in the trigeminal ganglion
Externí odkaz:
https://doaj.org/article/c5b38d86523848e28058a019a27e70a8
Autor:
Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, Masamichi Shinoda
Publikováno v:
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Trigeminal neuralgia is a characteristic disease that manifests as orofacial phasic or continuous severe pain triggered by innocuous orofacial stimulation; its mechanisms are not fully understood. In this study, we established a n
Externí odkaz:
https://doaj.org/article/fbc8e494947f40cf9d5daaceddd39b98
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-15 (2020)
Abstract Background The existence of referred pain and ectopic paresthesia caused by tooth pulp inflammation may make definitive diagnosis difficult and cause misdiagnosis or mistreatment; thus, elucidation of that molecular mechanism is urgent. In t
Externí odkaz:
https://doaj.org/article/65cfa9d53ee8474abc4461f0811977b5
Autor:
Masamichi Shinoda, Yoshiki Imamura, Yoshinori Hayashi, Noboru Noma, Akiko Okada-Ogawa, Suzuro Hitomi, Koichi Iwata
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Trigeminal nerve injury is known to cause severe persistent pain in the orofacial region. This pain is difficult to diagnose and treat. Recently, many animal studies have reported that rewiring of the peripheral and central nervous systems, non-neuro
Externí odkaz:
https://doaj.org/article/a1e510ca852142cd88372efe379e4351