Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Masamichi Hirose"'
Autor:
Yohei Sawa, Maki Saito, Nanae Ishida, Miho Ibi, Naoko Matsushita, Yoshihiro Morino, Eiichi Taira, Masamichi Hirose
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 1, Pp 16-25 (2020)
Recent studies demonstrated that sodium-glucose co-transporter 1 (SGLT1) is associated with human ischemic cardiomyopathy. However, whether SGLT1 blockade is effective against ischemic cardiomyopathy is still uncertain. We examined the effects of KGA
Externí odkaz:
https://doaj.org/article/8781f89ea6d64226b12dd58104ca0221
Autor:
Nanae Ishida, Maki Saito, Sachiko Sato, Yu Tezuka, Atsushi Sanbe, Eiichi Taira, Masamichi Hirose
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Previously, we showed that sodium/glucose cotransporter 1 (SGLT1) participates in vascular cognitive impairment in small vessel disease. We hypothesized that SGLT1 inhibitors can improve the small vessel disease induced‐vascular cognitive
Externí odkaz:
https://doaj.org/article/1e0e990177ba4dcf88705313dbc2b738
Autor:
Hidetoshi Yamada, Sayaka Kikuchi, Mayuka Hakozaki, Kaori Motodate, Nozomi Nagahora, Masamichi Hirose
Publikováno v:
Journal of Lipids, Vol 2016 (2016)
PPARs regulate the expression of genes involved in lipid homeostasis. PPARs serve as molecular sensors of fatty acids, and their activation can act against obesity and metabolic syndromes. 8-Hydroxyeicosapentaenoic acid (8-HEPE) acts as a PPAR ligand
Externí odkaz:
https://doaj.org/article/5105d7463d9c4be1a3e759c2f60c56c2
Autor:
Yoshiyuki Tanabe, Maki Saito, Yuki Morikawa, Akihisa Kamataki, Takashi Sawai, Masamichi Hirose, Koichi Nakayama
Publikováno v:
Journal of Pharmacological Sciences, Vol 115, Iss 4, Pp 525-531 (2011)
Involvement of secretory phospholipase A2 (sPLA2) in the stretch-induced production of untransformed prostaglandin H2 (PGH2) in the endothelium of rabbit pulmonary arteries was investigated. The stretch-induced contraction was significantly inhibited
Externí odkaz:
https://doaj.org/article/56b146f611e2453ab9e95090d0e007ab
Autor:
Naoko Matsushita, Toshihide Kashihara, Hisashi Shimojo, Satoshi Suzuki, Tsutomu Nakada, Yasuchika Takeishi, Ulrike Mende, Eiichi Taira, Mitsuhiko Yamada, Atsushi Sanbe, Masamichi Hirose
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e106354 (2014)
Transgenic mice with transient cardiac expression of constitutively active Galpha q (Gαq-TG) exhibt progressive heart failure and ventricular arrhythmias after the initiating stimulus of transfected constitutively active Gαq becomes undetectable. H
Externí odkaz:
https://doaj.org/article/645fbbeae7b649299460c15e1a616d18
Autor:
Masamichi Hirose, Yasuchika Takeishi, Tsutomu Nakada, Hisashi Shimojo, Toshihide Kashihara, Ayako Nishio, Satoshi Suzuki, Ulrike Mende, Kiyoshi Matsumoto, Naoko Matsushita, Eiichi Taira, Fumika Sato, Mitsuhiko Yamada
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52667 (2012)
BACKGROUND: Beneficial effects of nicorandil on the treatment of hypertensive heart failure (HF) and ischemic heart disease have been suggested. However, whether nicorandil has inhibitory effects on HF and ventricular arrhythmias caused by the activa
Externí odkaz:
https://doaj.org/article/9a75165fd9364367903c0befe0366274
Autor:
Atsushi, Sanbe, Yui, Inomata, Naoko, Matsushita, Yohei, Sawa, Chizuru, Hino, Hinano, Yamazaki, Kei, Takanohashi, Natsuko, Takahashi, Rieko, Higashio, Hideki, Tsumura, Toshinori, Aoyagi, Masamichi, Hirose
Publikováno v:
Biochemical and Biophysical Research Communications. 631:48-54
Histone deacetylase 6 (HDAC6) is known to deacetylate amino acid lysine in alpha-tubulin. However, the functional role of HDAC6 in the progression of cardiac disease remains uncertain. The functional role of HDAC6 in the hearts was examined using tra
Autor:
Masamichi Hirose, Eichi Taira, Mami Obara, Koji Nata, Kumi Takahashi, Yukiko Kondo, Sachiko Sato
Publikováno v:
Molecular and Cellular Biochemistry. 476:2021-2028
Gicerin/CD146 is a cell adhesion molecule which belongs to the immunoglobulin (Ig) superfamily. We have reported the existence of gicerin/CD146 in the nervous system, heart, lung and smooth muscles of blood vessels. In this study, we make a cardiac h
Autor:
Masamichi Hirose, Maki Saito, Naoko Matsushita, Miho Ibi, Eiichi Taira, Yoshihiro Morino, Yohei Sawa, Nanae Ishida
Publikováno v:
Journal of Pharmacological Sciences, Vol 142, Iss 1, Pp 16-25 (2020)
Recent studies demonstrated that sodium-glucose co-transporter 1 (SGLT1) is associated with human ischemic cardiomyopathy. However, whether SGLT1 blockade is effective against ischemic cardiomyopathy is still uncertain. We examined the effects of KGA
Autor:
Masamichi Hirose
Publikováno v:
International heart journal. 63(1)