Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Masamichi, Ikawa"'
Autor:
Tomohisa Yamaguchi, Tadanori Hamano, Kiyonao Sada, Rei Asano, Nicholas M. Kanaan, Hirohito Sasaki, Shu-Hui Yen, Yuki Kitazaki, Yoshinori Endo, Soichi Enomoto, Norimichi Shirafuji, Masamichi Ikawa, Osamu Yamamura, Youshi Fujita, Koji Aoki, Hironobu Naiki, Maho Morishima, Yuko Saito, Shigeo Murayama, Yasunari Nakamoto
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106656- (2024)
Spleen tyrosine kinase (Syk), a non-receptor-type tyrosine kinase, has a wide range of physiological functions. A possible role of Syk in Alzheimer's disease (AD) has been proposed. We evaluated the localization of Syk in the brains of patients with
Externí odkaz:
https://doaj.org/article/239a93f919264675ad69ceb404dfc1d2
Autor:
Hidehiko Okazawa, Munenobu Nogami, Shota Ishida, Akira Makino, Tetsuya Mori, Yasushi Kiyono, Masamichi Ikawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The glymphatic system is considered to play a pivotal role in the clearance of disease-causing proteins in neurodegenerative diseases. This study employed MR diffusion tensor imaging (DTI) to evaluate glymphatic system function and its corre
Externí odkaz:
https://doaj.org/article/da03fac5fd2d41f1a9626f13f00cf7c7
Autor:
Yuki Kitazaki, Masamichi Ikawa, Tadanori Hamano, Hirohito Sasaki, Tomohisa Yamaguchi, Soichi Enomoto, Norimichi Shirafuji, Kouji Hayashi, Osamu Yamamura, Tetsuya Tsujikawa, Hidehiko Okazawa, Hirohiko Kimura, Yasunari Nakamoto
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and objectivesMagnetic resonance imaging with arterial spin labeling (ASL) perfusion imaging is a noninvasive method for quantifying cerebral blood flow (CBF). We aimed to evaluate the clinical utility of ASL perfusion imaging to aid in th
Externí odkaz:
https://doaj.org/article/6572d88d913a4529bdbdb2314cc61ba7
Autor:
Hiroshi Kawamura, Masamichi Ikawa, Keiichi Hirono, Junya Kimura, Takashi Okuno, Masao Kawatani, Kunihiro Inai, Yukiko Hata, Naoki Nishida, Yoshio Yoshida
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundLeft ventricular noncompaction (LVNC) is a rare inherited cardiomyopathy with a broad phenotypic spectrum. The genotype-phenotype correlations in fetal-onset LVNC have not yet been fully elucidated. In this report, we present the first case
Externí odkaz:
https://doaj.org/article/906b3b58f7744e1198c679e0ae25c4f4
Autor:
Tadanori Hamano, Miwako Nagata, Rokuro Matsubara, Yukihiko Ikebata, Tatsuhiko Ito, Akihiro Ibe, Youshi Fujita, Yukinori Kusaka, Takahiro Tokunaga, Soichi Enomoto, Yoshinori Endo, Asako Ueno, Norimichi Shirafuji, Masamichi Ikawa, Kouji Hayashi, Osamu Yamamura, Yasunari Nakamoto
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2023)
Background: Early intervention for dementia patients is extremely important for the prevention of dementia. However, so far, it is not clear as to what kind of screening will be useful for the early detection of dementia.Objective: We aimed to invest
Externí odkaz:
https://doaj.org/article/2c41266e4bf24f189640877fdaeefcc8
Autor:
Hidehiko Okazawa, Masamichi Ikawa, Minyoung Jung, Rikiya Maruyama, Tetsuya Tsujikawa, Tetsuya Mori, Mahmudur G. M. Rahman, Akira Makino, Yasushi Kiyono, Hirotaka Kosaka
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Background Multimodal PET/MRI image data simultaneously obtained from patients with early-stage of Alzheimer’s disease (eAD) were assessed in order to observe pathophysiologic and functional changes, as well as alterations of morphology an
Externí odkaz:
https://doaj.org/article/a4cb02f6b38244399e375b0e210b5ea4
Autor:
Yuki Kitazaki, Norimichi Shirafuji, Naoko Takaku, Tomohisa Yamaguchi, Soichi Enomoto, Masamichi Ikawa, Osamu Yamamura, Yasunari Nakamoto, Tadanori Hamano
Publikováno v:
eNeurologicalSci, Vol 25, Iss , Pp 100382- (2021)
Autoimmune basal ganglia encephalitis causes neurological symptoms such as parkinsonism associated with basal ganglia lesions. Here, we report a case of autoimmune basal ganglia encephalitis without retinal lesions or malignancy harboring anti-recove
Externí odkaz:
https://doaj.org/article/433a536754e040c68ca4ac211ccd7fc8
Autor:
Hiroshi Matsuda, Kengo Ito, Kazunari Ishii, Eku Shimosegawa, Hidehiko Okazawa, Masahiro Mishina, Sunao Mizumura, Kenji Ishii, Kyoji Okita, Yoko Shigemoto, Takashi Kato, Akinori Takenaka, Hayato Kaida, Kohei Hanaoka, Keiko Matsunaga, Jun Hatazawa, Masamichi Ikawa, Tetsuya Tsujikawa, Miyako Morooka, Kenji Ishibashi, Masashi Kameyama, Tensho Yamao, Kenta Miwa, Masayo Ogawa, Noriko Sato
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Background: In clinical practice, equivocal findings are inevitable in visual interpretation of whether amyloid positron emission tomography (PET) is positive or negative. It is therefore necessary to establish a more objective quantitative evaluatio
Externí odkaz:
https://doaj.org/article/d804d17c8fd748caaeff8ee67474d60b
Autor:
Hidehiko Okazawa, Masamichi Ikawa, Tetsuya Tsujikawa, Tetsuya Mori, Akira Makino, Yasushi Kiyono, Yasunari Nakamoto, Hirotaka Kosaka, Makoto Yoneda
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 1022 (2022)
Oxidative stress imaging using diacetyl-bis (N4-methylthiosemicarbazone) (Cu-ATSM) was applied to the evaluation of patients with early Alzheimer’s disease (eAD). Ten eAD patients (72 ± 9 years) and 10 age-matched healthy controls (HCs) (73 ± 9 y
Externí odkaz:
https://doaj.org/article/668999fc4eee4f439eaaf3545b890eb9
Autor:
Tadanori Hamano, Tatsuro Mutoh, Hironobu Naiki, Norimichi Shirafuji, Masamichi Ikawa, Osamu Yamamura, Dennis W. Dickson, Shichiryoemon Aiki, Masaru Kuriyama, Yasunari Nakamoto
Publikováno v:
eNeurologicalSci, Vol 17, Iss , Pp - (2019)
Background: Neurofibromatosis 1 (NF1) is autosomally inherited disorder, characterized by café au lait spots and multiple neurofibromas. Subventricular glial nodules (SVGN) are multiple gliosis bulging into the ventricular lumen, and histologically
Externí odkaz:
https://doaj.org/article/4178bb75d8524d1488d46a4b8cc0b789