Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Masami YOSHIMURA"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 157-164 (2017)
The cyclic AMP (cAMP) signaling pathway is implicated in the development of alcohol use disorder. Previous studies have demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform specific manner; AC7 is most enhanced by et
Externí odkaz:
https://doaj.org/article/0878cafa536240909bd0e9865f9a4da7
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 347
To assess the role of adenylyl cyclase type 7 (AC7) in microglia’s immune function, we generated AC7 gene knockout (AC7 KO) clones from a mouse microglial cell line, BV-2, using the CRISPR-Cas9 gene editing system. The ability of BV-2 cells to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d1fd333681a64f5ddb15a010ac0f7b
https://doi.org/10.3390/ijms24010347
https://doi.org/10.3390/ijms24010347
Publikováno v:
Biochemistry and Biophysics Reports, Vol 10, Iss C, Pp 157-164 (2017)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
The cyclic AMP (cAMP) signaling pathway is implicated in the development of alcohol use disorder. Previous studies have demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform specific manner; AC7 is most enhanced by et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7123b0e04c9755207acc97b89144780
http://www.sciencedirect.com/science/article/pii/S2405580816303715
http://www.sciencedirect.com/science/article/pii/S2405580816303715
Publikováno v:
Biochemistry and Biophysics Reports
Previous research has indicated that the cyclic AMP (cAMP) signal transduction system plays an important role in the predisposition to and development of ethanol abuse in humans. Our laboratory has demonstrated that ethanol is capable of enhancing ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e0d38d71204ce6e52dadae2cf5ba64
Autor:
Humberto Munoz Barona, James P. Geaghan, Masami Yoshimura, Shaomian Yao, Fakhri Al-Bagdadi, Eduardo Martinez-Ceballos, Matthew J. Young
Publikováno v:
Ultrastructural Pathology. 40:324-332
It is estimated that 5.9% of all human deaths are attributable to alcohol consumption and that the harmful use of ethanol ranks among the top five risk factors for causing disease, disability, and death worldwide. Ethanol is known to disrupt phosphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eb97702776a3334ee4536dffa49bbb
https://doi.org/10.1080/01913123.2016.1233160
https://doi.org/10.1080/01913123.2016.1233160
Autor:
Yawen Hu, Masami Yoshimura
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13719fa5d3f83b2a94d9b6e5276c10fc
https://doi.org/10.1096/fasebj.2018.32.1_supplement.545.21
https://doi.org/10.1096/fasebj.2018.32.1_supplement.545.21
Autor:
Yawen Hu, Masami Yoshimura
Publikováno v:
The Journal of Immunology. 202:187.14-187.14
Alcohol consumption modulates immune responses. However, the mechanisms of ethanol’s action on the immune system are not fully understood. Previous studies demonstrated that ethanol enhances the activity of adenylyl cyclase (AC) in an isoform-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8693d0c886be7f4fb53f764794c2278a
https://doi.org/10.4049/jimmunol.202.supp.187.14
https://doi.org/10.4049/jimmunol.202.supp.187.14
Publikováno v:
Alcoholism: Clinical and Experimental Research. 35:1915-1922
Background: Our previous studies showed that ethanol enhanced the activity of adenylyl cyclase (AC) in an isoform-specific manner and that alcohol cutoff point of AC was isoform specific. Recently, we showed that 2,3-butanediol inhibited AC type 7 (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f980eb71e23be91abc96fb6bb90b43d4
https://doi.org/10.1111/j.1530-0277.2011.01542.x
https://doi.org/10.1111/j.1530-0277.2011.01542.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 34:743-749
Background: Our previous studies showed that the activity of adenylyl cyclase (AC) was enhanced by pharmacologically relevant concentrations of ethanol, that this enhancing effect of ethanol on AC activity was AC isoform specific, and that the alcoho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477634b424629cfb689be748c3d67c2c
https://doi.org/10.1111/j.1530-0277.2009.01144.x
https://doi.org/10.1111/j.1530-0277.2009.01144.x
Autor:
Oksana M. Subach, Jinghang Zhang, Dmitriy M. Chudakov, Masami Yoshimura, David Gruenwald, Illia S. Gundorov, Ekaterina A. Souslova, Vladislav V. Verkhusha, Fedor V. Subach
Publikováno v:
Chemistry & Biology. 15(10):1116-1124
SummaryWe used a red chromophore formation pathway, in which the anionic red chromophore is formed from the neutral blue intermediate, to suggest a rational design strategy to develop blue fluorescent proteins with a tyrosine-based chromophore. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de4776553400642cdb7467d1403ee5e