Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Masami Shimizu"'
Autor:
Baohai Shao, Masami Shimizu-Albergine, Farah Kramer, Jenny E. Kanter, Jay W. Heinecke, Tomas Vaisar, Bettina Mittendorfer, Bruce W. Patterson, Karin E. Bornfeldt
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 4, Pp 100531- (2024)
Altered apolipoprotein kinetics play a critical role in promoting dyslipidemia and atherogenesis. Human apolipoprotein kinetics have been extensively evaluated, but similar studies in mice are hampered by the lack of robust methods suitable for the s
Externí odkaz:
https://doaj.org/article/eb7bb67902ae41f8935f1f4dd33cf409
Autor:
Hye Seung Jung, Masami Shimizu-Albergine, Xia Shen, Farah Kramer, Dan Shao, Anuradha Vivekanandan-Giri, Subramaniam Pennathur, Rong Tian, Jenny E. Kanter, Karin E. Bornfeldt
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 33-44 (2020)
Chronic inflammation contributes to cardiovascular disease. Increased levels of the inflammatory cytokine, TNF-α, are often present in conditions associated with cardiovascular disease risk, and TNF-α induces a number of pro-atherogenic effects in
Externí odkaz:
https://doaj.org/article/7680d29b12544a35b2fbd65148406143
Autor:
Amélie E Bigorgne, Beena John, Mohammad R Ebrahimkhani, Masami Shimizu-Albergine, Jean S Campbell, Ian N Crispe
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151063 (2016)
Background & aimsThe gut microbiota significantly influences hepatic immunity. Little is known on the precise mechanism by which liver cells mediate recognition of gut microbes at steady state. Here we tested the hypothesis that a specific liver cell
Externí odkaz:
https://doaj.org/article/c5e7e0d2e95d4fdda06251cce4aee92b
Autor:
Brian J Hayes, Kimberly J Riehle, Masami Shimizu-Albergine, Renay L Bauer, Kelly L Hudkins, Fredrik Johansson, Matthew M Yeh, William M Mahoney, Raymond S Yeung, Jean S Campbell
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92925 (2014)
Chronic liver injury leads to fibrosis, cirrhosis, and loss of liver function. Liver cirrhosis is the 12th leading cause of death in the United States, and it is the primary risk factor for developing liver cancer. Fibrosis and cirrhosis result from
Externí odkaz:
https://doaj.org/article/9ff3d0d101784f8d98c19a247a1f8660
Autor:
Didem Demirbas, Arlene R Wyman, Masami Shimizu-Albergine, Ozgur Cakici, Joseph A Beavo, Charles S Hoffman
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71279 (2013)
A cell-based high-throughput screen (HTS) was developed to detect phosphodiesterase 8 (PDE8) and PDE4/8 combination inhibitors. By replacing the Schizosaccharomyces pombe PDE gene with the murine PDE8A1 gene in strains lacking adenylyl cyclase, we ge
Externí odkaz:
https://doaj.org/article/93923a8aea084547805499afdd9abfba
Autor:
Yunosuke Matsuura, Masami Shimizu-Albergine, Shelley Barnhart, Farah Kramer, Cheng-Chieh Hsu, Vishal Kothari, Jingjing Tang, Sina A. Gharib, Jenny E. Kanter, E. Dale Abel, Rong Tian, Baohai Shao, Karin E. Bornfeldt
Publikováno v:
Circ Res
This manuscript was sent to Joyce Bischoff, Guest Editor, for review by expert referees, editorial decision, and final disposition. Final decisions were approved by Jane Leopold, Guest Editor-in-Chief.
Publikováno v:
Journal of the Faculty of Agriculture, Kyushu University. 66:1-10
Autor:
Martin Golkowski, Michael-Claude G. Beltejar, Karin E. Bornfeldt, Shao En Ong, Masami Shimizu-Albergine, Joseph A. Beavo
Publikováno v:
Mol Pharmacol
In recent years, highly sensitive mass spectrometry–based phosphoproteomic analysis is beginning to be applied to identification of protein kinase substrates altered downstream of increased cAMP. Such studies identify a very large number of phospho
Autor:
Jingjing Tang, Vishal Kothari, Tomas Vaisar, Masami Shimizu-Albergine, Farah Kramer, Jeremy M Frey, Jenny E Kanter, Karin E Bornfeldt
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
ADAM17 (A Disintegrin-like And Metalloproteinase 17) is a transmembrane protease that cleaves its substrates at the cell surface. Cell type-specific substrates cleaved by ADAM17, such as TNFα, can function locally and systemically. When fed a diet e
Autor:
Dan Shao, Jenny E. Kanter, Rong Tian, Anuradha Vivekanandan-Giri, Masami Shimizu-Albergine, Farah Kramer, Karin E. Bornfeldt, Subramaniam Pennathur, Hye Seung Jung, Xia Shen
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 33-44 (2020)
J Lipid Res
J Lipid Res
Chronic inflammation contributes to cardiovascular disease. Increased levels of the inflammatory cytokine, TNF-α, are often present in conditions associated with cardiovascular disease risk, and TNF-α induces a number of pro-atherogenic effects in