Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Masami Komiya"'
Autor:
Shugo Suzuki, Min Gi, Masami Komiya, Asuka Obikane, Arpamas Vachiraarunwong, Masaki Fujioka, Anna Kakehashi, Yukari Totsuka, Hideki Wanibuchi
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 36 (2023)
Occupational exposure to aromatic amines (AAs) is an important risk factor for urinary bladder cancer. This study aimed to evaluate the toxicity of AAs and analyze the carcinogenic mechanisms in rat bladder by comprehensive analysis of DNA adducts (D
Externí odkaz:
https://doaj.org/article/5736d78940a84bb2b95745b9e94d7678
Autor:
Masami Komiya, Rikako Ishigamori, Mie Naruse, Masako Ochiai, Noriyuki Miyoshi, Toshio Imai, Yukari Totsuka
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Short-/middle-term and simple prediction studies for carcinogenesis are needed for the safety assessment of chemical substances. To establish a novel genotoxicity assay with an in vivo mimicking system, we prepared murine colonic/pulmonary organoids
Externí odkaz:
https://doaj.org/article/15724e95d15948518b7d967014cde8a5
Autor:
Shuya Tamura, Takumi Narita, Gen Fujii, Shingo Miyamoto, Takahiro Hamoya, Yurie Kurokawa, Maiko Takahashi, Kouhei Miki, Yui Matsuzawa, Masami Komiya, Masaru Terasaki, Tomohiro Yano, Michihiro Mutoh
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background Evidence from epidemiological and experimental studies has shown that the etiology of colorectal cancer (CRC) is related to lifestyle, mainly diet. At the same time, there are many foods and beverages that have been shown to provi
Externí odkaz:
https://doaj.org/article/ec0c413ce4d34e018e3b80a4265d87a3
Autor:
Rikako Ishigamori, Masami Komiya, Shinji Takasu, Michihiro Mutoh, Toshio Imai, Mami Takahashi
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 5, p 1058 (2017)
Osteopontin (OPN) is a secreted phosphoglycoprotein, and is a transcriptional target of aberrant Wnt signaling. OPN is upregulated in human colon cancers, and is suggested to enhance cancer progression. In this study, the effect of deficiency of OPN
Externí odkaz:
https://doaj.org/article/e163661cbe6649bcaf541eedce4db3d6
Autor:
TAKUMI NARITA, YUTA TSUNEMATSU, NORIYUKI MIYOSHI, MASAMI KOMIYA, TAKAHIRO HAMOYA, GEN FUJII, YUKO YOSHIKAWA, MICHIO SATO, MASANOBU KAWANISHI, HARUHIKO SUGIMURA, YUJI IWASHITA, YUKARI TOTSUKA, MASARU TERASAKI, KENJI WATANABE, KEIJI WAKABAYASHI, MICHIHIRO MUTOH
Publikováno v:
In Vivo. 36:628-634
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0681acb6e06618aeea0d97087604f458
https://doi.org/10.21873/invivo.12746
https://doi.org/10.21873/invivo.12746
Autor:
Toshiyuki Sakai, Yosuke Iizumi, Tadashi Kondo, Kohei Miki, Jiro Toshima, Yui Matsuzawa, Takahiro Hamoya, Kenji Watanabe, Michihiro Mutoh, Takumi Narita, Masami Komiya, Gen Fujii, Keiji Wakabayashi, Shinji Kishimoto
Publikováno v:
Carcinogenesis. 42:148-158
Artesunate (ART) is a clinically approved antimalarial drug and was revealed as a candidate of colorectal cancer chemopreventive agents in our drug screening system. Here, we aimed to understand the suppressive effects of ART on intestinal tumorigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd1c45dad2dde7394d0a05124f8f93b
https://doi.org/10.1093/carcin/bgaa084
https://doi.org/10.1093/carcin/bgaa084
Autor:
Saeko Adachi, Hideki Ishikawa, Tetsuji Takayama, Takahiro Hamoya, Michihiro Mutoh, Takumi Narita, Maiko Takahashi, Kosuke Tashiro, Masami Komiya, Gen Fujii, Shingo Miyamoto, Yurie Kurokawa
Publikováno v:
Cancer Science
Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. Therefore, it is important to establish useful methods for preventing CRC. One prevention strategy involves the use of cancer chemopreventive agents, including functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ce4a702254c3e6d2ac95fc9a3ef19f
https://doi.org/10.1111/cas.14329
https://doi.org/10.1111/cas.14329
Autor:
Takumi, Narita, Yuta, Tsunematsu, Noriyuki, Miyoshi, Masami, Komiya, Takahiro, Hamoya, Gen, Fujii, Yuko, Yoshikawa, Michio, Sato, Masanobu, Kawanishi, Haruhiko, Sugimura, Yuji, Iwashita, Yukari, Totsuka, Masaru, Terasaki, Kenji, Watanabe, Keiji, Wakabayashi, Michihiro, Mutoh
Publikováno v:
In Vivo
Background/Aim: Among colorectal cancer-associated intestinal microbiota, colibactin-producing (clb(+)) bacteria are attracting attention. We aimed to clarify the interaction between clb(+) Escherichia coli and normal colorectal epithelial cells in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43ebe7d2438dc966ec4deb8e2e29a94a
https://pubmed.ncbi.nlm.nih.gov/35241515
https://pubmed.ncbi.nlm.nih.gov/35241515
Autor:
Takumi Narita, Gen Fujii, Masami Komiya, Kohei Miki, Maiko Takahashi, Yui Matsuzawa, Yurie Kurokawa, Michihiro Mutoh, Takahiro Hamoya
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 65:203-208
It has been reported that activation of NF-E2 p45-related factor-2 (NRF2), a transcription factor, induces a variety of antioxidant enzymes, and plays an important role in preventing carcinogenesis. AHCC is a standardized extract of cultured Lentinul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a0b57f3b8230c430a7064d9db8ec165
https://doi.org/10.3164/jcbn.19-36
https://doi.org/10.3164/jcbn.19-36
Autor:
Kosuke Tashiro, Michihiro Mutoh, Masahito Hagio, Maiko Takahashi, Gen Fujii, Takahiro Hamoya, Takumi Narita, Masami Komiya, Yukari Totsuka
Publikováno v:
In Vivo
Background/Aim: Οverweight and obesity are risk factors for chronic diseases. Dietary calcium has been reported to exert anti-obesity effects. However, the complex modulating effects of calcium intake on obese mice have not been clarified. Materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd0245658df2ae1fc9f33cfd276e726
https://pubmed.ncbi.nlm.nih.gov/34182486
https://pubmed.ncbi.nlm.nih.gov/34182486