Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Masami Kojima"'
Autor:
Mayuko Ichimura-Shimizu, Khuleshwari Kurrey, Misaki Miyata, Takuya Dezawa, Koichi Tsuneyama, Masami Kojima
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 444 (2024)
Brain-derived neurotrophic factor (BDNF) is a growth factor that promotes the survival and growth of developing neurons. It also enhances circuit formation to synaptic transmission for mature neurons in the brain. However, reduced BDNF expression and
Externí odkaz:
https://doaj.org/article/30775691a0aa4cfba5b5e6a6482c5b42
Autor:
Eero Castrén, Masami Kojima
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 119-126 (2017)
Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of depressed patients and at least the reduction in serum levels is reversible upon successful treatment. These data, together with a wealth of reports using differ
Externí odkaz:
https://doaj.org/article/13b03a41fdac43c0b6772f0d7be22ccb
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 7, Pp 1024-1027 (2017)
Most growth factors are initially synthesized as precursors and it was cleaved into bioactive mature domain and pro-domain. However, compared with the expression and function of bioactive mature domain, the biological role of the pro-domain is poorly
Externí odkaz:
https://doaj.org/article/f685c75b128343b083011ccaf4b671fb
Publikováno v:
AIMS Materials Science, Vol 3, Iss 4, Pp 1728-1747 (2016)
This paper aims to describe the effect of tool geometry on cutting characteristics of a 1.0 mm thickness acrylic worksheet subjected to a punch/die shearing. A set of side-wedge punch and side-wedge die which had the edge angle of 30°, 60° and/or 9
Externí odkaz:
https://doaj.org/article/c34a43e818834456b9e36e9bcb86f314
Autor:
Yasuo Yoshitomi, Hiromi Osada, Haruka Satake, Masami Kojima, Hidehito Saito-Takatsuji, Takayuki Ikeda, Yoshino Yoshitake, Yasuhito Ishigaki, Eri Kubo, Hiroshi Sasaki, Hideto Yonekura
Publikováno v:
Biology Open, Vol 8, Iss 2 (2019)
Ultraviolet (UV) radiation of eyes is a major risk factor for cataractogenesis, although the molecular mechanisms underlying this process remain poorly understood and genes that are affected by UV radiation have not been fully identified. In this stu
Externí odkaz:
https://doaj.org/article/413e4baa1bd146e1aeebaaa6e677ce5f
Autor:
Masami Kojima, Hikari Otabi, Haruko Kumanogoh, Atsushi Toyoda, Masahito Ikawa, Masaru Okabe, Toshiyuki Mizui
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 3984 (2020)
We generated a knock-in mouse line in which the gene encoding brain-derived neurotrophic factor (Bdnf) was replaced with a sequence for proBDNF containing human single nucleotide polymorphisms encoding arginines proximal to the cleavage site (R125M a
Externí odkaz:
https://doaj.org/article/fda2b4fcda724546971415d5aac72a0a
Publikováno v:
Data Science Journal, Vol 6, Pp 137-144 (2007)
The purpose of this study is to develop a plausible method to code and compile Buddhist texts from original Tibetan scripts into Romanized form. Using GUI (Graphical User Interface) based on Object Oriented Design, a dictionary of Tibetan characters
Externí odkaz:
https://doaj.org/article/2aa568b5306d4bfeb50ffe1972bab54f
Autor:
Yoshitaka Tomiyama, Makoto Murakami, Kohichi Hayakawa, Katsuyoshi Akiyama, Yoshinobu Yamazaki, Masami Kojima, Nobuo Shibata, Masuo Akahane
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 4, Pp 411-419 (2003)
Since, in the human ureter, both β2- and β3-adrenoceptors mediate adrenergic-stimulation-induced relaxation, selective β2-/β3-adrenoceptor agonists might prove clinically useful for relieving ureteral colic and promoting stone passage. We evaluat
Externí odkaz:
https://doaj.org/article/06363c70edbd48bf866b9f1e881497f3
Autor:
Tetsushi Sadakata, Wataru Kakegawa, Yo Shinoda, Mayu Hosono, Ritsuko Katoh-Semba, Yukiko Sekine, Yumi Sato, Chihiro Saruta, Yasuki Ishizaki, Michisuke Yuzaki, Masami Kojima, Teiichi Furuichi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99524 (2014)
Ca2+-dependent activator protein for secretion 2 (CAPS2) is a protein that is essential for enhanced release of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from cerebellar granule cells. We previously identified dex3, a rare al
Externí odkaz:
https://doaj.org/article/428e526d7b8d4bd2ac50337e2309ab46
Autor:
Tomi Rantamäki, Susanna Kemppainen, Henri Autio, Saara Stavén, Hennariikka Koivisto, Masami Kojima, Hanna Antila, Pasi O Miettinen, Elisa Kärkkäinen, Nina Karpova, Liisa Vesa, Lothar Lindemann, Marius C Hoener, Heikki Tanila, Eero Castrén
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68722 (2013)
Brain-derived neurotrophic factor (BDNF) importantly regulates learning and memory and supports the survival of injured neurons. Reduced BDNF levels have been detected in the brains of Alzheimer's disease (AD) patients but the exact role of BDNF in t
Externí odkaz:
https://doaj.org/article/c57728a0617c488a94514e4337b67faa