Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Masami Horikoshi"'
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3941-3956 (2017)
While both archaeal and eukaryotic transcription initiation systems utilize TBP (TATA box-binding protein) and TFIIB (transcription factor IIB), eukaryotic systems include larger numbers of initiation factors. It remains uncertain how eukaryotic tran
Externí odkaz:
https://doaj.org/article/bc180ffdd8724499a3751d43297234bc
Autor:
Masami Horikoshi
Publikováno v:
Biomedical Research and Reviews. 2
Publikováno v:
Proceedings of the National Academy of Sciences. 111:699-704
Currently, there is no method to distinguish between the roles of a subunit in one multisubunit protein complex from its roles in other complexes in vivo. This is because a mutation in a common subunit will affect all complexes containing that subuni
Autor:
Masami Horikoshi
Publikováno v:
Current Pharmaceutical Design. 19:5019-5042
Structural changes of chromatin, which consists of nucleosomes and nucleosome-associated factors, lead to functional changes that are important determinants of eukaryotic gene regulation. These structural changes are regulated by modifications of his
Publikováno v:
Scientific Reports
TBP and TFIIB are evolutionarily conserved transcription initiation factors in archaea and eukaryotes. Information about their ancestral genes would be expected to provide insight into the origin of the RNA polymerase II-type transcription apparatus.
Autor:
Yu Nakabayashi, Masami Horikoshi, Takemi Enomoto, Hirohito Endo, Masayuki Seki, Satoshi Kawashima
Publikováno v:
Genes to Cells. 17:65-81
A nucleosome is composed of intrinsically disordered histone tails and a structured nucleosome core surrounded by DNA. A variety of modifiable residues on the intrinsically disordered histone tails have been identified in the last decade. Mapping of
Autor:
Masayuki Seki, Tatsuya Ohsumi, Shusuke Tada, Lena R. Kundu, Masami Horikoshi, Katsuyuki Ishikawa, Ryo Natsume, Naohito Nozaki, Toshiya Senda, Takemi Enomoto
Publikováno v:
Genes to Cells. 16:1050-1062
The nucleosome, which is composed of DNA wrapped around a histone octamer, is a fundamental unit of chromatin and is duplicated during the eukaryotic DNA replication process. The evolutionarily conserved histone chaperone cell cycle gene 1 (CCG1) int
Autor:
Yasunari Takami, Takemi Enomoto, Akari Yoshimura, Motomu Akita, Masami Horikoshi, Shunichi Takeda, Katsuzumi Okumura, Tatsuo Nakayama, Shusuke Tada, Hiromu Murofushi, Masayuki Seki, Takuya Abe, Yoshifumi Hosono, Kazuto Sugimura
Publikováno v:
Journal of Biological Chemistry. 286:30504-30512
Ordered nucleosome disassembly and reassembly are required for eukaryotic DNA replication. The facilitates chromatin transcription (FACT) complex, a histone chaperone comprising Spt16 and SSRP1, is involved in DNA replication as well as transcription
Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation
Autor:
Takemi Enomoto, Masami Horikoshi, Kazuko Matsubara, Kozo Tanaka, Satoshi Kawashima, Norihiko Sano, Masayuki Seki, Yu Nakabayashi
Publikováno v:
The EMBO Journal. 30:3353-3367
The attachment of sister kinetochores to microtubules from opposite spindle poles is essential for faithful chromosome segregation. Kinetochore assembly requires centromere‐specific nucleosomes containing the histone H3 variant CenH3. However, the
Publikováno v:
Genes to Cells. 16:590-607
Histone variants perform unique functions and are deposited onto DNA by mechanisms distinct from those of canonical histones. The H2A variant, H2A.Z, also known as Htz1 in Saccharomyces cerevisiae, is not uniformly distributed across the genome but f