Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Masami, Nagahama"'
Autor:
Arthur Louche, Amandine Blanco, Thais Lourdes Santos Lacerda, Lison Cancade-Veyre, Claire Lionnet, Célia Bergé, Monica Rolando, Frédérique Lembo, Jean-Paul Borg, Carmen Buchrieser, Masami Nagahama, Francine C. A. Gérard, Jean-Pierre Gorvel, Virginie Gueguen-Chaignon, Laurent Terradot, Suzana P. Salcedo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The bacterium Brucella abortus is an intracellular pathogen that modulates autophagy in host cells. Here, the authors identify two B. abortus effectors that interact with host protease SENP3, thus promoting cytoplasmic accumulation of nucleolar prote
Externí odkaz:
https://doaj.org/article/d17ea5f6891f46cf844a7cebbda821aa
Publikováno v:
Cells, Vol 12, Iss 4, p 602 (2023)
Genetic variations of CD33 have been implicated as a susceptibility factor of Alzheimer’s disease (AD). A polymorphism on exon 2 of CD33, rs12459419, affects the alternative splicing of this exon. The minor allele is associated with a reduced risk
Externí odkaz:
https://doaj.org/article/4c52555c732340c6ab035a20f6e34109
Autor:
Toshimichi Yamada, Naoto Imamachi, Katsutoshi Imamura, Kenzui Taniue, Takeshi Kawamura, Yutaka Suzuki, Masami Nagahama, Nobuyoshi Akimitsu
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: RNA-binding proteins (RBPs) play a pivotal role in gene expression by modulating the stability of transcripts. However, the identification of degradation target mRNAs of RBPs remains difficult. By the combined analysis of transcriptome-wide
Externí odkaz:
https://doaj.org/article/4b519f4df52943fda03af74d378c6bde
Publikováno v:
Biochemical and Biophysical Research Communications. 637:203-209
Ribosome biogenesis proceeds with the successive cleavage and trimming of the large 47S rRNA precursor, where the RNA exosome plays major roles in concert with the Ski2-like RNA helicase, MTR4. The recent finding of a consensus amino acid sequence, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74234f2a1b1488aaa1f93231b464f739
https://doi.org/10.1016/j.bbrc.2022.11.018
https://doi.org/10.1016/j.bbrc.2022.11.018
Autor:
Naoko Fujiwara, Maki Shigemoto, Mizuki Hirayama, Ken-ichi Fujita, Shigeto Seno, Hideo Matsuda, Masami Nagahama, Seiji Masuda
Publikováno v:
Nucleic Acids Research. 50:8779-8806
Recent in vitro reconstitution analyses have proven that the physical interaction between the exosome core and MTR4 helicase, which promotes the exosome activity, is maintained by either MPP6 or RRP6. However, knowledge regarding the function of MPP6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c243fe2ee4b1178b239da5dbabc87db
https://doi.org/10.1093/nar/gkac559
https://doi.org/10.1093/nar/gkac559
Autor:
Xiaoning Sun, Atsuko Miki, Masami Nagahama, Nobuyoshi Akimitsu, Kentaro Kawata, Akiko Takaya, Youichiro Wada
Publikováno v:
BioScience Trends. 14:255-262
Salmonella enterica serovar Typhimurium (Salmonella), a pathogenic bacterium, is a major cause of foodborne diseases worldwide. Salmonella injects multiple virulence factors, called effectors, into cells and causes multiple rearrangements of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b325d5af136a7de1d01a1c109350fc4
https://doi.org/10.5582/bst.2020.03085
https://doi.org/10.5582/bst.2020.03085
Publikováno v:
Biochemical and Biophysical Research Communications. 495:116-123
WD repeat-containing protein 74 (WDR74), a nucleolar-localized protein, is the mammalian ortholog of Nsa1, a 60S ribosome assembly factor in yeast. We previously showed that WDR74 associates with MTR4, the nuclear exosome-assisting RNA helicase, whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f412829d724d7fdb2a942105c572951b
https://doi.org/10.1016/j.bbrc.2017.10.148
https://doi.org/10.1016/j.bbrc.2017.10.148
Autor:
Tomohiro Udagawa, Koji L. Ode, Yuko Kajiho, Masaomi Nangaku, Seiya Urae, Akira Oka, Masami Nagahama, Akihiko Saito, Shoichiro Kanda, Hiroki R. Ueda, Yutaka Harita
Publikováno v:
Journal of cell science. 133(13)
Cubilin (CUBN) and amnionless (AMN), expressed in kidney and intestine, form a multiligand receptor complex called CUBAM that plays a crucial role in albumin absorption. To date, the mechanism of albumin endocytosis mediated by CUBAM remains to be el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bedcb7d2a0772d873970e499f15bb14
https://pubmed.ncbi.nlm.nih.gov/32482797
https://pubmed.ncbi.nlm.nih.gov/32482797
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 132:105919
The AAA-ATPase NVL2 associates with an RNA helicase MTR4 and the nuclear RNA exosome in the course of ribosome biogenesis. In our proteomic screen, we had identified a ribosome biogenesis factor WDR74 as a MTR4-interacting partner, whose dissociation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0b44ef0f128e3fe2aab7d577cc32ea
https://doi.org/10.1016/j.biocel.2021.105919
https://doi.org/10.1016/j.biocel.2021.105919
Publikováno v:
FEBS Letters. 590:2963-2972
In yeast, the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) complex acts as a cofactor for the nuclear exosome to promote degradation of various RNAs. However, the corresponding machinery in mammals is less characterized. We analyzed the interactions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49473bbb3b2b84807bd2f8ef0a7432c
https://doi.org/10.1002/1873-3468.12314
https://doi.org/10.1002/1873-3468.12314