Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Masakuni Okuhara"'
Publikováno v:
Journal of Japan Association on Odor Environment. 51:129-143
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26a4ccab5b470d6931dcaed090148d1
https://doi.org/10.2171/jao.51.129
https://doi.org/10.2171/jao.51.129
Autor:
Toshiro Iwamoto, Akihiko Fujie, Tomoko Nakanishi, Kazutoshi Sakamoto, Motohiro Hino, Seiji Hashimoto, Hideyuki Muramatsu, Yasuhiro Hori, Masakuni Okuhara, Terumi Okudaira, Kumiko Nitta
Publikováno v:
The Journal of Antibiotics. 53:912-919
FR901469 is a novel antifungal antibiotic produced by an unidentified fungus No.11243. This compound was isolated from the culture broth by solvent extraction, HP-20 and YMC ODS gel column chromatography, and lyophilization. FR901469 is a white powde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be8623e7a9a41eed61b2b8c42f212f7
https://doi.org/10.7164/antibiotics.53.912
https://doi.org/10.7164/antibiotics.53.912
Autor:
Yoshitada Notsu, Yasuhiko Shinguh, Akiko Yamazaki, Takaharu Ono, Kunio Nakahara, Keiko Fujie, Noriaki Inamura, Masakuni Okuhara, Masanori Okamoto
Publikováno v:
European Journal of Pharmacology. 345:299-308
FR134043, disodium(Z,1S,15S,8S,24S,27R,29S,34S,37R)-29-ben zyl-21-ethylidene-27-hydroxy-15-isobutyrylamino-34-isopropyl-31,37 -dimethyl-10,16,19,22,30,32,35,38-octaoxo-36-oxa-9,11,17,20,23,28, 31,33-octaazatetracyclo[16.13.6.1(24),(28).0(3),(8)]octat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301d78c055dce0fc7b6af1c624006f44
https://doi.org/10.1016/s0014-2999(98)00028-4
https://doi.org/10.1016/s0014-2999(98)00028-4
Autor:
Masanori Okamoto, Yasuhisa Tsurumi, Masakuni Okuhara, Seiji Yoshimura, Yuko Muramatsu, Takanao Otsuka, Hiroshi Hatanaka, Seiji Hashimoto
Publikováno v:
The Journal of Antibiotics. 51:1-7
WA8242A1, A2 and B, novel inhibitors of secretory phospholipase A2, were obtained from the cultured mycelium of Streptomyces violaceusniger No. 8242. WA8242A1, A2 and B are structurally related compounds with α-aminoadipic acid and with various leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b3cf080327c80ec031e24aafecfff6
https://doi.org/10.7164/antibiotics.51.1
https://doi.org/10.7164/antibiotics.51.1
Autor:
Kunio Nakahara, Teruo Oku, Noriaki Inamura, Masayuki Asano, Takayuki Inoue, Akira Katayama, Hiroe Sawai, Hiroshi Kayakiri, Chie Hatori, Yoshito Abe, Masakuni Okuhara, Tatsujiro Fujiwara, Yuki Sawada, Shigeki Satoh
Publikováno v:
British Journal of Pharmacology. 120:617-624
1. An orally active, nonpeptide bradykinin (BK) B2 receptor antagonist, FR173657 (E)-3-(6-acetamido-3-pyridyl)-N-[N-[2-4-dichloro-3-[(2-methyl-8-quinolin yl) oxymethyl]phenyl]-N-methylaminocarbonyl-methyl] acrylamide) has been identified. 2. This com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d997df4c90a71a7c9072cc58d1c0d395
https://doi.org/10.1038/sj.bjp.0700955
https://doi.org/10.1038/sj.bjp.0700955
Autor:
Kazuhiko Ohne, Yoshitada Notsu, Akira Nagayoshi, Yoshikuni Ito, Kunio Nakahara, Masakuni Okuhara, Hiroyuki Hagihara, Yuri Sakuma, Seitaro Mutoh
Publikováno v:
Life Sciences. 60:351-356
Recent studies have shown that acyl-CoA:cholesterol acyltransferase (ACAT) plays an important role in the initiation of diabetes-associated hypercholesterolemia. To confirm this hypothesis, effects of a potent ACAT inhibitor, FR145237, on diet-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bff8b1d6de2fa3a2ab98723cd068216
https://doi.org/10.1016/s0024-3205(96)00658-3
https://doi.org/10.1016/s0024-3205(96)00658-3
Publikováno v:
Current Microbiology. 33:89-93
This strain 758 of a new member of Flexibacter species isolated from a soil is a Gram-negative, nonflagellated, gliding, long rod or filamentous. The GC contents of the deoxyribonucleic acid of this strain is 49.8 mol %GC. The isolate can be distingu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd00e2354c222fca5fed7b346bcd23f5
https://doi.org/10.1007/s002849900080
https://doi.org/10.1007/s002849900080
Autor:
Hiroshi Terano, Shigehiro Takase, Hidenori Nakajima, Bunji Sato, Takashi Fujita, Masakuni Okuhara
Publikováno v:
The Journal of Antibiotics. 49:1196-1203
New antitumor substances, FR901463, FR901464 and FR901465 were isolated from the culture broth of a bacterium of Pseudomonas sp. No.2663. FR901463, FR901464 and FR901465 remarkably enhanced the transcriptional activity of the promoter of SV40 DNA vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0ce0a8f300055de0fbdd1b6a8c67fd
https://doi.org/10.7164/antibiotics.49.1196
https://doi.org/10.7164/antibiotics.49.1196
Autor:
Akira Nagayoshi, Masakuni Okuhara, Kazuhiko Ohne, Yoshikuni Ito, Yoshitada Notsu, Yuri Sakuma, Hiroyuki Hagihara, Seitaro Mutoh
Publikováno v:
Japanese Journal of Pharmacology. 70:35-41
FR129169 (FR) (N-(l,2-diphenylethyl)-2-octyloxyphenylacetamide) has been found to inhibit acyl-CoA:cholesterol acyltransferase (ACAT) activities in intestinal microsomes of rats and rabbits and the liver homogenate of rats with IC50 values of around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fc62abb47e4b1d1f042b45b36e6fcd
https://doi.org/10.1254/jjp.70.35
https://doi.org/10.1254/jjp.70.35
Autor:
Shizue Izumi, Tomoko Nakanishi, Masakuni Okuhara, Kazutoshi Sakamoto, Michio Yamashita, Eisaku Tsujii, Fumie Abe, Nobuharu Shigematsu
Publikováno v:
The Journal of Antibiotics. 49:37-44
FR901483, a novel immunosuppressant, has been isolated from the fermentation broth of Cladobotryum sp. No. 11231. The molecular formula of FR901483 has been determined as C20H31N2O6P. FR901483 exerts a potent immunosuppressive activity in vitro and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f9517fcd1475be3430cd820fa9f6e1
https://doi.org/10.7164/antibiotics.49.37
https://doi.org/10.7164/antibiotics.49.37