Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Masakuni Furusato"'
Autor:
Takahiro Kimura, Hidetoshi Kuruma, Masakuni Furusato, Hiroyuki Takahashi, Masahito Kido, Hiroyuki Inaba, Bungo Furusato, Shin Egawa, Mioko Okayasu, Tetsuro Wada, Toshihiro Yamamoto
Publikováno v:
Journal of Urology. 195:1415-1420
The incidence of prostate cancer is reported to be increasing in Asia, including Japan. Although this trend has been attributed partly to a more Western diet, this assumption may involve variable confounders. Thus, we examined the histological featur
Autor:
Takahiro Kimura, Hiroyuki Takahashi, Geert J.H.L. van Leenders, Masakuni Furusato, Hiroshi Hano, Bungo Furusato, Shin Egawa, Tapio Visakorpi, J. Trapman
Publikováno v:
Pathology International. 61:409-414
Chromosomal rearrangements that result in high expression levels of the ETS-related gene (ERG) present in approximately 50% of prostate cancer (PCa) patients, making this one of the most common oncogenic alterations in PCa. However, ERG overexpressio
Autor:
Kiyofumi Yokoo, Hiroshi Hano, Hiroyuki Takahashi, Tomoko Muto, Yoshihiko Suzuki, Hitoshi Endou, Masakuni Furusato, Shin Wakui, Yoshikatsu Kanai
Publikováno v:
Laboratory Investigation. 86:1172-1184
Endothelial cells and pericytes play critical role in angiogenesis, which is controlled, in part, by the angiopoietin (Ang)/Tie-2 system and vascular endothelial growth factor (VEGF). Here, we investigated Ang, Tie-2, and VEGF expression within endot
Autor:
Chenxi Meng, Hiroyuki Takahashi, Wei Lu, Yasushi Kikuchi, Hiroshi Hano, Masataka Nakano, Suguru Maekawa, Akemi Sudo, Masakuni Furusato
Publikováno v:
The Prostate. 66:405-412
BACKGROUND Loss of heterozygosity (LOH) at 13q is one of the most common chromosomal alterations in high-stage prostate cancer, yet little is known about genetic changes in earlier-stage prostate cancer. METHODS We used five microsatellite markers at
Autor:
Masatoshi Watanabe, Tomoko Muto, Isao Ikemoto, Hiroshi Hano, Takahiko Katoh, Koichiro Akakura, Hiroyoshi Suzuki, Masakuni Furusato, Hiroyuki Takahashi, Akemi Sudo, Kouji Asano, Shin Wakui, Takaaki Ito, Hiroyuki Nakao, Wei Lu, Hiromasa Tsukino
Publikováno v:
International Journal of Cancer. 107:224-228
The HPC2/ELAC2 gene may be associated with hereditary/familial prostate cancer (PCa). Two common missense variants (Ser217Leu and Ala541Thr) have been reported in the gene. We performed mutational, allelotyping and expression analyses and a molecular
Autor:
Hiroyuki Takahashi, Noboru Imano, Shin Wakui, Masakuni Furusato, Hiroshi Hano, Tomoko Muto, Kenji Nakaaki
Publikováno v:
Toxicology Letters. 143:271-277
Alterations of estrous cyclicity and ovarian follicles following prenatal exposure to PCB126 were examined. Female SD rats were given (i.g.) 25 pg, 2.5, 250 ng and 7.5 microg of PCB126/kg or the vehicle on days 13-19 postconception. Vaginal opening (
Autor:
Toshiaki Manabe, Yoshihiro Matsuno, Taizo Shiraishi, Yoshiki Mikami, Hironobu Sasano, Toyonori Tsuzuki, Jonathan I. Epstein, Masakuni Furusato
Publikováno v:
Human Pathology. 34:658-665
The aims of this study were to evaluate the accuracy of Gleason grading for prostatic adenocarcinoma among practicing pathologists in Japan and to determine the influence of education on this accuracy. Using a case-oriented approach, 16 hematoxylin a
Publikováno v:
Okayama Igakkai Zasshi (Journal of Okayama Medical Association). 115:33-37
Autor:
Shin Wakui, Noboru Imano, Tomoko Muto, Toshio Masaoka, Kenji Nakaaki, Masakuni Furusato, Hiroshi Hano
Publikováno v:
Journal of Toxicologic Pathology. 14:213-224
While polychlorinated biphenyls (PCB) are fat-soluble environmental pollutants stored breast fatty tissue and secreted in milk; the precise evidence of breast carcinoma from exposure to PCBs remains unclear. The aim of this study was to investigate t
Autor:
Hiroyuki Takahashi, Taizo Shiraishi, Hiroshi Hano, Hiroyoshi Suzuki, Kazuo Fukutome, Shuntaro Ikawa, Masakuni Furusato, Masatoshi Watanabe, Haruo Ito
Publikováno v:
The Prostate. 47:85-90
BACKGROUND p73 and p51 are genes possessing amino-acid similarities to p53. We previously found no mutation in p73 in prostatic carcinoma, but did find abnormal expression of the gene. Involvement of these genes in prostatic carcinogenesis is still p