Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Masako Takasu"'
Autor:
Ayame Kobayashi, Motokuni Nakajima, Yoh Noguchi, Ryota Morikawa, Yukiko Matsuo, Masako Takasu
Publikováno v:
Life, Vol 13, Iss 2, p 578 (2023)
Alzheimer’s disease is an irreversible neurological disorder for which there are no effective small molecule therapeutics. A phosphodiesterase 5 (PDE5) inhibitor is a candidate medicine for the treatment of Alzheimer’s disease. Rutaecarpine, an i
Externí odkaz:
https://doaj.org/article/8daf6fbab5584da29fafe73b2106a974
Publikováno v:
Life, Vol 13, Iss 2, p 306 (2023)
The characteristic shape changes observed in the growth and division of L-form cells have been explained by several theoretical studies and simulations using a vesicle model in which the membrane area increases with time. In those theoretical studies
Externí odkaz:
https://doaj.org/article/5650363367514e668211e0362ddeb77a
Autor:
Hironao Yamada, Sakiko Mori, Takeshi Miyakawa, Ryota Morikawa, Fumihiko Katagiri, Kentaro Hozumi, Yamato Kikkawa, Motoyoshi Nomizu, Masako Takasu
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149474 (2016)
Peptides with cell attachment activity are beneficial component of biomaterials for tissue engineering. Conformational structure is one of the important factors for the biological activities. The EF1 peptide (DYATLQLQEGRLHFMFDLG) derived from laminin
Externí odkaz:
https://doaj.org/article/5675ca44add848348c14811b97f034dd
Autor:
Hidemi Nagao, Ryota Morikawa, Kazutomo Kawaguchi, Takeshi Miyakawa, Masako Takasu, Kimikazu Sugimori
Publikováno v:
Proceedings of the 2020 10th International Conference on Bioscience, Biochemistry and Bioinformatics.
Hras protein is an intermediate for signals of cell proliferation and cell differentiation when Hras combines with guanosine triphosphate (GTP). In ordinary cells, GTP combined with Hras is hydrolyzed to guanosine diphosphate (GDP), and the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::069cb27473c053c224bf7bef592677b1
https://doi.org/10.1145/3386052.3386059
https://doi.org/10.1145/3386052.3386059
Autor:
Tatsuya Uchida, Takeshi Miyakawa, Akihiko Yamagishi, Ryota Morikawa, Keiichi Nobuoka, Hironao Yamada, Masako Takasu, Mao Watabe
Publikováno v:
Proceedings of the 2020 10th International Conference on Bioscience, Biochemistry and Bioinformatics.
Proteins that specifically bind to metals have been used for research on development of new organic-inorganic hybrid materials. Several peptides and proteins that bind to metals have been reported; this property can be attributed to their structures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9048a30189a10543a41500fd825ac53f
https://doi.org/10.1145/3386052.3386057
https://doi.org/10.1145/3386052.3386057
Autor:
Takeshi Miyakawa, Takuya Watanabe, Ryota Morikawa, Keiichi Nobuoka, Masako Takasu, Hironao Yamada
Publikováno v:
Proceedings of the 2020 10th International Conference on Bioscience, Biochemistry and Bioinformatics.
Chemerin-9 is a nonapeptide that corresponds to the YFPGQFAFS sequence on the C-terminus of Chemerin protein. Recent clinical and animal studies using mice, it has been recently reported that Chemerin-9 binds to the ChemR23 receptor and can suppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbbfb6c667fa5cf991afbecbff89f2df
https://doi.org/10.1145/3386052.3386055
https://doi.org/10.1145/3386052.3386055
Autor:
Yukio Hitotsuyanagi, Ryota Morikawa, Masako Takasu, Hironao Yamada, Yoh Noguchi, Satoshi Yokojima, Sakiko Mori, Takeshi Miyakawa, Koichi Takeya
Publikováno v:
Molecular Simulation. 44:73-84
We computationally examined the structure of anti-tumour bicyclic hexapeptide RA-VII. This peptide adopts three conformations (confs.), A, B and C, in dimethyl sulfoxide (DMSO). Although it was exp...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c31ba8341307229c335d8c50d5239e6b
https://doi.org/10.1080/08927022.2017.1342122
https://doi.org/10.1080/08927022.2017.1342122
Publikováno v:
Physical Review E. 99
Experimental observations indicate that the repulsion of particles is a factor that induces the transformation of vesicles containing multiple particles. Metropolis Monte Carlo simulations are performed with two models in which repulsive particles ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273aa0ba1022273c55256845b1a6b94f
https://doi.org/10.1103/physreve.99.042418
https://doi.org/10.1103/physreve.99.042418
Autor:
K. Nobuoka, Y. K. Hayashi, H. Okajima, Takeshi Miyakawa, Masako Takasu, Hibiki Itoga, Ryota Morikawa, H. Takeuchi, H. Yamada
Publikováno v:
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019).
Mutations in the FHL1 gene can cause X-linked hereditary myopathy, which causes one of the rarest intractable diseases. The age of the disease onset is quite variable from early infancy to adulthood, and the patients show progressive muscle weakness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::604f3088892284f25b24bf4e72c7536e
https://doi.org/10.1063/1.5137923
https://doi.org/10.1063/1.5137923
Autor:
Hiroki Takeuchi, Ryota Morikawa, Hiroki Okajima, Takeshi Miyakawa, Masako Takasu, Hironao Yamada, Yukiko K. Hayashi
Publikováno v:
Proceedings of the 2018 8th International Conference on Bioscience, Biochemistry and Bioinformatics.
Myopathy is a rare disease lacking a fundamental therapy. Several genetic factors are involved in myopathy; those caused by mutations in FHL1 are rare. We performed molecular dynamics simulation of the LIM2 domain in FHL1 (four and a half LIM domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f1a18a80c52b539877e1ed5c586cb2
https://doi.org/10.1145/3180382.3180386
https://doi.org/10.1145/3180382.3180386