Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Masako SASAKI"'
Autor:
Misato Nakanishi-Koakutsu, Kenji Miki, Yuki Naka, Masako Sasaki, Takayuki Wakimizu, Stephanie C. Napier, Chikako Okubo, Megumi Narita, Misato Nishikawa, Reo Hata, Kazuhisa Chonabayashi, Akitsu Hotta, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Current differentiation protocols for human induced pluripotent stem cells (hiPSCs) produce heterogeneous cardiomyocytes (CMs). Although chamber-specific CM selection using cell surface antigens enhances biomedical applications, a cell surfa
Externí odkaz:
https://doaj.org/article/73e8538871d040e3ae7023f2f88a2a49
Autor:
Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C. Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) suffer from limited maturation. Here the authors identify ERRγ agonist as a factor that enhances cardiac morphological, metabolic, contractile and electrical maturation
Externí odkaz:
https://doaj.org/article/e591e23480c3403b95a1cc6ecca9b455
Autor:
Mitsunobu Oba, Yoshitsugu Nakanishi, Tomoko Mitsuhashi, Katsunori Sasaki, Kanako C. Hatanaka, Masako Sasaki, Ayae Nange, Asami Okumura, Mariko Hayashi, Yusuke Yoshida, Takeo Nitta, Takashi Ueno, Toru Yamada, Masato Ono, Shota Kuwabara, Keisuke Okamura, Takahiro Tsuchikawa, Toru Nakamura, Takehiro Noji, Toshimichi Asano, Kimitaka Tanaka, Kiyoshi Takayama, Yutaka Hatanaka, Satoshi Hirano
Publikováno v:
Cancers, Vol 15, Iss 6, p 1878 (2023)
The epithelial–mesenchymal transition (EMT) contributes to the metastatic cascade in various tumors. C-C chemokine receptor 7 (CCR7) interacts with its ligand, chemokine (C-C motif) ligand 19 (CCL19), to promote EMT. However, the association betwee
Externí odkaz:
https://doaj.org/article/27c5b411d76a42038eacf2928c534354
Publikováno v:
Annals of Human Biology, Vol 46, Iss 4, Pp 340-346 (2019)
Background: Increasing dietary fibre (DF) intake through a habitual diet is recommended for preventing diabetes. Aim: To investigate a stepwise approach to nutrition education on DF intake among young adults in Japan with the largest deficit in habit
Externí odkaz:
https://doaj.org/article/039c78c74a174a71a765dcecce967644
Publikováno v:
Annals of Human Biology, Vol 46, Iss 4, Pp 311-322 (2019)
Context: The average Japanese lifespan became the longest in the world in 1986. What factors give the Japanese this longevity? Washoku, or the traditional Japanese diet, is respected globally for its nutritionally-balanced and healthy eating habits.
Externí odkaz:
https://doaj.org/article/ad3ad8adbf534c7a94ae0e79d6e17505
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 17, Iss , Pp - (2020)
Purpose: To describe features characteristic of vitreous hemorrhage in patients with Terson syndrome observed through a microsurgical scope. Methods: Between May 2015 and February 2019, 12 eyes of 10 patients with vitreous hemorrhage occurring after
Externí odkaz:
https://doaj.org/article/7cc8f82b84614445909f9aa374fa007f
Autor:
Masako Sasaki, Ikuo Miyahisa, Sachiko Itono, Hiroaki Yashiro, Hideyuki Hiyoshi, Kazue Tsuchimori, Ken‐ichi Hamagami, Yusuke Moritoh, Masanori Watanabe, Kimio Tohyama, Minoru Sasaki, Jun‐ichi Sakamoto, Tomohiro Kawamoto
Publikováno v:
Pharmacology Research & Perspectives, Vol 7, Iss 5, Pp n/a-n/a (2019)
Abstract Enteropeptidase, localized into the duodenum brush border, is a key enzyme catalyzing the conversion of pancreatic trypsinogen proenzyme to active trypsin, thereby regulating protein digestion and energy homeostasis. We report the discovery
Externí odkaz:
https://doaj.org/article/6a80d3a9b6c84d77bac6dd6c17560898
Publikováno v:
Journal of Pharmacological Sciences, Vol 100, Iss 4, Pp 263-270 (2006)
Abstract.: The thromboxane A2 receptor (TP), one of the G protein-coupled receptors (GPCRs), consists of two splicing variants, TPα and TPβ, which differ in their C-terminal regions. In the present study, we investigated whether TPα and TPβ forme
Externí odkaz:
https://doaj.org/article/d210a73e21124da991538a2731cfecfc
Publikováno v:
Antarctic Record, Vol 45, Iss 1, Pp 1-12 (2001)
To analyze characteristics of solar ultraviolet irradiance in the ozone hole region, solar ultraviolet-B (UV-B : 280-315nm) and ultraviolet-A (UV-A : 315-400nm) irradiance at noon were measured from October 4,1999 to January 31,2000 at Syowa Station
Externí odkaz:
https://doaj.org/article/3dd1e00de3734f5f9ca0bc75e8aab505
Autor:
Shinji Iwasaki, Hironobu Yasuno, Derek M. Erion, Yumiko Okano Tamura, Masako Sasaki, Jun Sugama, Kazunobu Aoyama, Hiroaki Yashiro, Masanori Watanabe
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 379:280-289
Acetyl-CoA carboxylase (ACC) 1 and ACC2 are essential rate-limiting enzymes that synthesize malonyl-CoA (M-CoA) from acetyl-CoA. ACC1 is predominantly expressed in lipogenic tissues and regulates the de novo lipogenesis flux. It is upregulated in the