Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Masako Nomiyama"'
Publikováno v:
Clinical and Experimental Nephrology. 2:117-123
Background We previously found that ticlopidine inhibits the proliferation of cultured rat mesangial cells that is induced by fetal bovine serum. This study was designed to examine the effects of ticlopidine on platelet-derived growth factor (PDGF)-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd3eb3667f8aace36c0cf95c1ee15c9
https://doi.org/10.1007/bf02479932
https://doi.org/10.1007/bf02479932
Publikováno v:
Japanese Journal of Hospital Pharmacy. 24:17-22
The effect of two anti-platelet drugs, ticlopidine and dilazep, on the fetal bovine serum (FBS)-induced DNA synthesis of cultured rat renal mesangial cells was assessed by means of an [3H] thymidine incorporation assay. Each drug inhibited the 2% FBS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8753ded114dd13d93f179c2e28ec5597
https://doi.org/10.5649/jjphcs1975.24.17
https://doi.org/10.5649/jjphcs1975.24.17
Autor:
Fumiaki Kitazawa, Kazuki Nagasawa, Teruyoshi Yokoyama, Noriaki Ohnishi, Masako Nomiyama, Toshiki Natazuka, Akiko Tsumura, Kazuo Chihara, Kohji Takara
Publikováno v:
Cancer Chemotherapy and Pharmacology. 37:297-304
We studied the transport mechanism of pirarubicin (THP) in HL60 and its THP-resistant (HL60/THP) cells, which showed no expression of mdr1 mRNA on Northern blot analysis. Under physiological conditions, the uptake of THP by both types of cell was tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dbeab61b21d5ad678921a44d3933a2
https://doi.org/10.1007/s002800050389
https://doi.org/10.1007/s002800050389
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:100-105
We examined the transport mechanisms of daunorubicin (DNR) and doxorubicin (ADR) in HL60 and HL60/THP cells which were the non-P-glycoprotein-mediated resistant clone of the parent HL60 cells and showed a low degree of resistance, and compared them w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5012f7ab7d8150a255cd3adc7a97caf3
https://doi.org/10.1248/bpb.19.100
https://doi.org/10.1248/bpb.19.100
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:1203-1209
We studied the transport mechanism of pirarubicin (THP) in mononuclear cells (MNCs) obtained from healthy human donors. The THP uptake was time-, temperature-, concentration- and energy (in part)-dependent. The uptake of daunorubicin (DNR) and doxoru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1ba18bc58f640263cc435db3a53d38
https://doi.org/10.1248/bpb.19.1203
https://doi.org/10.1248/bpb.19.1203
Publikováno v:
Biological and Pharmaceutical Bulletin. 19:971-976
We studied the uptake mechanisms of anthracycline derivatives, pirarubicin (THP), daunorubicin (DNR) and doxorubicin (ADR), in K562 and multidrug-resistant K562/ADM cells, which overexpress a multidrug efflux pump P-glycoprotein (P-gp). The uptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33aa5700be1a9c6966092902c0355bd0
https://doi.org/10.1248/bpb.19.971
https://doi.org/10.1248/bpb.19.971
Autor:
Teruyoshi Yokoyama, Masako Nomiyama, Kazuki Nagasawa, Noriaki Ohnishi, Akiko Tsumura, Fumiaki Kitazawa
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:368-371
We previously revealed that pirarubicin (THP) was actively taken up by rat polymorphonuclear leukocytes via a carrier-mediated transport system. In the experiment on the effects of the metabolic inhibitors, rotenone, 2,4-dinitrophenol and sodium cyan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f449fd8402c70aba5987b779285178
https://doi.org/10.1248/bpb.18.368
https://doi.org/10.1248/bpb.18.368
Autor:
Katsuhiko Okumura, Seigo Iwakawa, Kazuki Nagasawa, Noriaki Ohnishi, Masako Nomiyama, Teruyoshi Yokoyama
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:1305-1308
We performed experiments on the cis-inhibition and trans-stimulation effect on pirarubicin uptake in order to clarify the involvement of a carrier in the pirarubicin, daunorubicin and/or doxorubicin transport systems in rat polymorphonuclear leukocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11daed5014cf93bb50513237e9f4c5a
https://doi.org/10.1248/bpb.17.1305
https://doi.org/10.1248/bpb.17.1305
Autor:
Teruyoshi Yokoyama, Katsuhiko Okumura, Noriaki Ohnishi, Kazuki Nagasawa, Masako Nomiyama, Seigo Iwakawa
Publikováno v:
Biologicalpharmaceutical bulletin. 17(5)
The characteristics of pirarubicin transport have been investigated in polymorphonuclear leukocytes isolated from rats. The uptake of pirarubicin by leukocytes was time-, temperature- and concentration-dependent with the maximum velocity (Vmax) of 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70fb99da35b4a316004296f23393c717
https://pubmed.ncbi.nlm.nih.gov/7920436
https://pubmed.ncbi.nlm.nih.gov/7920436